Now showing items 1-20 of 23

    • Aymara children are protected from high-altitude-induced pulmonary hypertension 

      Stuber, Thomas; Sartori, Claudio; Hutter, Damian; Salinas Salmón, Carlos E; Thalmann, Sebastien; Turini, Pierre; Jayet, Pierre-Yves; Villena, Mercedes; Scherrer, Urs; Allemann, Yves (High Altitude Medicine & Biology, 2005-02-22)
      Pulmonary hypertension is a hallmark of the adaptation to ambient lack of oxygen. This assumption is also thought to hold true for high-altitude native children, since invasive studies showed elevated pulmonary-artery pressure ...
    • Cardio-respiratory studies in chronic mountain sickness (Monge's syndrome) 

      Ergueta, J; Spielvogel, Hilde; Cudkowicz, L (Revista del IBBA, 1972)
      Abstract. Comparisons with 14 normal, younger, male native residents of La Paz showed that 20 patients with Monge’s syndrome have significantly higher mean body surface areas, hemoglobin, resting tidal volumes [VT (BTPS)], ...
    • Chronic mountain sickness, optimal hemoglobin and heart disease 

      Vargas, Enrique; Spielvogel, Hilde (High Altitude Medicine & Biology, 2006-06)
      Abstract. For the male inhabitants of La Paz, Bolivia (3200–4100 m), and other high altitude regions in America and Asia, chronic mountain sickness (CMS) is a major health problem. Since CMS was first described by Carlos ...
    • Consensus statement on chronic and subacute high altitude diseases 

      León-Velarde, Fabiola; Maggiorini, Marco; Reeves, John T; Aldashev, Almaz; Asmus, Ingrid; Bernardi, Luciano; Ge, Ri-Li; Hackett, Peter; Kobayashi, Toshio; Moore, Lorna G; Peñaloza, Dante; Richalet, Jean-Paul; Roach, Robert; Wu, Tianyi; Vargas, Enrique; Zubieta-Castillo, Gustavo; Zubieta-Calleja, Gustavo (High Altitude Medicine & Biology, 2005)
      ABSTRACT. This is an international consensus statement of an ad hoc committee formed by the In ternational Society for Mountain Medicine (ISMM) at the VI World Congress on Mountain Med icine and High Altitude Physiology ...
    • Los efectos de elevada altitud en la hipertensión pulmonar de cardiópatas en La Paz Bolivia 

      Antezana, Gerardo (Instituto Boliviano de Biología de Altura, 1970)
    • Effets des contraintes thermiques sur la circulation pulmonaire de l'homme a l'altitude 

      Coudert, J; Guieu, JD; Antezana, G; Spielvogel, H; Zelter, M; Menschdechene, J; Geyssant, A; Durand, J (INSERM, 1977)
      RESUME. L'hypoxie est considérée comme Ie principal facteur responsable de l'hypertension pulmonaire (H.T.P.) des résidents de haute-altitude. Dans ce travail on a étudié d'autres facteurs tels que le froid et Ia chaleur, ...
    • Estudios cardiorespiratorios en la enfermedad crónica de la montaña (Síndrome de Monge) 

      Ergueta, Jorge; Spielvogel, Hilde; Cudkowicz, Leon (Revista IBBA, 1972)
      Resumen. Comparación entre 14 individuos normales jóvenes del sexo masculino y 20 enfermos con síndrome de Monge. Se mostró que éstos últimos tienen una superficie corporal media, una hemoglobina, volumen tidal en reposo ...
    • Exaggerated exercise-induced pulmonary hypertension causes lung water accumulation and right ventricular dysfunction in patients with chronic mountain sickness 

      Pratali, Lorenza; Rimoldi, Stefano F; Rexhaj, Emrush; Salinas Salmón, Carlos E; Villena, Mercedes; Sicari, Rosa; Picano, Eugenio; Scherrer, Urs; Allemann, Yves; Sartori, Claudio (High Altitude Medicine & Biology, 2010-08-08)
    • Exaggerated pulmonary hypertension and right ventricular dysfunction in high-altitude dwellers with patent foramen ovale 

      Brenner, Roman; Pratali, Lorenza; Rimoldi, Stefano F; Murillo Jauregui,Carla Ximena; Soria, Rodrigo; Rexhaj, Emrush; Salinas Salmón, Carlos; Villena, Mercedes; Romero, Catherine; Sartori, Claudio; Allemann, Yves; Scherrer, Urs (Chest, 2015)
      There is considerable interindividual variability in pulmonary artery pressure among high-altitude (HA) dwellers, but the underlying mechanism is not known. At low altitude, a patent foramen ovale (PFO) is present in about ...
    • Exaggerated pulmonary hypertension during mild exercise in chronic mountain sickness 

      Stuber, Thomas; Sartori, Claudio; Schwab, Marcos; Jayet, Pierre-Yves; Rimoldi, Stefano F; Garcin, Sophie; Thalmann, Sébastien; Spielvogel, Hilde; Salinas Salmón, Carlos E; Villena, Mercedes; Scherrer, Urs; Allemann, Yves (CHEST, 2010-02)
      Background: Chronic mountain sickness (CMS) is an important public health problem and is characterized by exaggerated hypoxemia, erythrocytosis, and pulmonary hypertension. While pulmonary hypertension is a leading cause ...
    • Exposición crónica a la altura. Características clínicas y diagnóstico 

      Santos-Martínez, Luis E; Gómez-Tejada, Ricardo A; Murillo-Jauregui, Carla X; Hoyos-Paladines, Rodrigo A; Poyares-Jardim, Carlos V; Orozco-Levi, Mauricio (Arch Cardiol Mex, 2021)
      Resumen La exposición crónica a la altitud se ha asociado a hipoxia hipobárica en quienes la experimentan. Dos entidades se han asociado a la hipoxia hipobárica: la hipertensión pulmonar de la alta altitud y el mal de ...
    • High-altitude hypoxia and echocardiographic indices of pulmonary hypertension in male and female chickens at adulthood 

      Salinas Salmón, Carlos E; Blanco, Carlos E; Villena, Mercedes; Giussani, Dino A (Circulation Journal, 2014-06)
      Background: By combining the chick embryo model with incubation at high altitude (HA), the effects of chronic hypoxia on fetal growth, fetal cardiac and aortic wall remodeling and systemic arterial blood pressure at adulthood ...
    • Hipertensión arterial pulmonar y la eritrocitosis precede a la enfermedad pulmonar obstructiva crónica en fumadores residentes de grandes alturas 

      Velarde Zegada, Ariel; Vásquez Durán, Gustavo; Villena Cabrera, Mercedes (ARS MÉDICA, 2022)
      Resumen Introducción: la eritrocitosis excesiva afecta a los habitantes de grandes alturas como La Paz, Bolivia, a 3600 msnm. El objetivo del presente trabajo es determinar la existencia de hipertensión arterial pulmonar ...
    • Nuevos mecanismos para hipertensión arterial pulmonar en la altura 

      Salinas Salmón, Carlos (COLEGIO MEDICO DE BOLIVIA, 2016-02)
      RESUMEN. Durante la última década el alcance de la investigación en la altura se ha ampliado considerablemente. Dos importantes observaciones han generado este avance; Primero, el hecho de que el edema pulmonar agudo de ...
    • Persistance du canal artériel hypertension pulmonaire en altitude 

      Caballero, GP; Rodríguez, FL; Pantajo, JV; Gutiérrez, ML (Coeur, 1976)
      Resume. 1. A l’occasion de l’expérience chirurgicale réalisée par l’I.N.T. à La Paz, en Bolivie (3500 m d’altitude), on a constaté les résultats suivants : sur un total de 440 cas ayant subi une intervention de chirurgie ...
    • Preeclampsia and risk of maternal pulmonary hypertension at high altitude in Bolivia 

      Salinas, CE; Patey, OV; Murillo, C; Gonzales, M; Espinoza, V; Mendoza, S; Ruiz, R; Vargas, R; Perez, Y; Montaño, J; Toledo-Jaldin, L; Badner, A; Jimenez, J; Peñaranda, J; Romero, C; Aguilar, M; Riveros, L; Arana, I; Giussani, DA (Journal of Developmental Origins of Health and Disease, 2023)
      Abstract. Women with a history of preeclampsia (PE) have a greater risk of pulmonary arterial hypertension (PAH). In turn, pregnancy at high altitude is a risk factor for PE. However, whether women who develop PE during ...
    • Protective effect of female sex hormones against pulmonary hypertension in Bolivian high altitude natives 

      Sartori, Claudio; Allemann, Yves; Salinas Salmón, Carlos E; Turini, Pierre; Rodríguez, Armando; Hutter, Damián; Thalmann, Sébastien; Vargas, Enrique; Villena, Mercedes; Scherrer, Urs (High Altitude Medicine & Biology, 2003-02-19)
      There is abundant evidence that female sex hormones have protective effects in the systemic circulation in both animals and humans, but little is known regarding their role in the regulation of the pulmonary circulation. ...
    • Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia 

      Jayet, Pierre-Yves; Rimoldi, Stefano F; Stuber, Thomas; Salinas Salmón, Carlos E; Hutter, Damian; Rexhaj, Emrush; Thalmann, Sébastien; Schwab, Marcos; Turini, Pierre; Sartori-Cucchia, Céline; Nicod, Pascal; Villena, Mercedes; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (Circulation, 2010-07-19)
      Background—Adverse events in utero may predispose to cardiovascular disease in adulthood. The underlying mechanisms are unknown. During preeclampsia, vasculotoxic factors are released into the maternal circulation by the ...
    • Pulmonary hypertension in high-altitude chronic hypoxia : response to nifedipine 

      Antezana, AM; Antezana, G; Aparicio, Olga; Noriega, I; Velarde, FL; Richalet, J-P (European Respiratory Journal, 1998-11)
      ABSTRACT. Permanent residents at high altitude may develop excessive polycythaemia (H-Hb) and pulmonary hypertension, which often leads to cardiac failure. Inhibitors of calcium channels have been shown to reverse pulmonary ...
    • Regional distribution of pulmonary blood flow in normal high-altitude dwellers at 3,650 m (12,200 ft) 

      Coudert, J; Paz-Zamora, M; Barragán, L; Briançon, L; Spielvogel, H; Cudkowicz, L (Respiration, 1975)
      Abstract. Simultaneous isotope dilution curves were recorded from the right upper (QRUZ) and right lower lung zones (QRLZ) by surface scanning in the sitting and recumbent positions in 15 normal high-altitude-born (HAD) ...