Listar IBBA - Instituto Boliviano de Biología de la Altura por autor "Villena, Mercedes"

Mostrando ítems 1-20 de 64

    • Adrenocortical suppression in highland chick embryos is restored during incubation at sea level 

      Salinas Salmón, Carlos E; Villena, Mercedes; Blanco, Carlos E; Giussani, Dino A (High Altitude Medicine & Biology, 2011)
      Abstract. By combining the chick embryo model with incubation at high altitude, this study tested the hypothesis that development at high altitude is related to a fetal origin of adrenocortical but not adrenomedullary ...

    • Ancient human genomes suggest three ancestral populations for present-day Europeans 

      Lazaridis, Iosif; Patterson, Nick; Mittnik, Alissa; Renaud, Gabriel; Mallick, Swapan; Kirsanow, Karola; Sudmant, Peter H; Schraiber, Joshua G; Castellano, Sergi; Lipson, Mark; Berger, Bonnie; Economou, Christos; Bollongino, Ruth; Fu, Q; Bos, Kirsten I; Nordenfelt, Susanne; Li, Heng; Filippo, Cesare de; Prüfer, Kay; Sawyer, Susanna; Posth, Cosimo; Haak, Wolfgang; Hallgren, Fredrik; Fornander, Elin; Rohland, Nadin; Delsate, Dominique; Francken, Michael; Guinet,Jean-Michel; Wahl, Joachim; Ayodo,George; Babiker, Hamza A; Bailliet. Graciela; Balanovska, Elena; Balanovsky,Oleg; Barrantes, Ramiro; Bedoya, Gabriel; Ben-Ami, Haim; Bene, Judit; Berrada, Fouad; Bravi, Claudio M; Brisighelli, Francesca; Busby, George BJ; Cali, Francesco; Churnosov, Mikhail; Cole, David EC; Corach, Daniel; Damba, Larissa; Driem, George van; Dryomov, Stanislav; Dugoujon, Jean-Michel; Fedorova, Sardana A; Gallego Romero, Irene; Gubina, Marina; Hammer, Michael; Henn, Brenna M; Hervig,Tor; Hodoglugil, Ugur; Jha, Aashish R; Karachanak-Yankova, Sena; Khusainova, Rita; Khusnutdinova, Elza; Kittles, Rick; Kivisild, Toomas; Klitz, William; Kucinskas, Vaidutis; Kushniarevich, Alena; Laredj, Leila; Litvinov, Sergey; Loukidis, Theologos; Mahley, Robert W; Melegh, Béla; Metspalu, Ene; Molina, Julio; Mountain, Joanna; Näkkäläjärvi, Klemetti; Nesheva, Desislava; Nyambo, Thomas; Osipova, Ludmila; Parik, Jüri; Platonov, Fedor; Posukh, Olga; Romano, Valentino; Rothhammer, Francisco; Rudan, Igor; Ruizbakiev, Ruslan; Sahakyan, Hovhannes; Sajantila, Antti; Salas, Antonio; Starikovskaya, Elena B; Tarekegn, Ayele; Toncheva, Draga; Turdikulova, Shahlo; Uktveryte, Ingrida; Utevska,Olga; Vasquez, René; Villena, Mercedes; Voevoda, Mikhail; Winkler, Cheryl A; Yepiskoposyan, Levon; Zalloua, Pierre; Zemunik, Tatijana; Cooper, Alan; Capelli, Cristian; Thomas, Mark G; Ruiz-Linares, Andres; Tishkoff, Sarah A; Singh, Lalji; Thangaraj, Kumarasamy; Villems, Richard; Comas, David; Sukernik, Rem; Metspalu, Mait; Meyer, Matthias; Eichler, Evan E; Burger, Joachim; Slatkin, Montgomery; Pääbo, Svante; Kelso, Janet; Reich, David; Krause, Johannes (Nature, 2014-09-18)
      We sequenced the genomes of a 7,000-year-old farmer from Germanyandeight 8,000-year-oldhunter-gatherersfromLuxembourg and Sweden. We analysed these and other ancient genomes1–4 with 2,345contemporaryhumanstoshowthatmostp ...

    • Andean compared with european women are protected from altitude-associated intrauterine growth restriction (IUGR) 

      Moore, Lorna G; Armaza, Fernando; Keyes, L; Borth, R; Niermeyer, Susan; Villena, Mercedes; MacCannell, Wendy; Vargas, Enrique (s.n., 2003)
      Abstract. Babies born at high altitude to long-term high-altitude residents weigh more than those of recent migrants from low altitude. Objective: We asked whether a gradient exists such that persons of Andean ancestry ...

    • Apolipoprotein E/C1/C4/C2 gene cluster diversity in two native andean populations : Aymaras and Quechuas 

      Gayá-Vidal, Magdalena; Athanasiadis, Georgios; Carreras-Torres, Robert; Via, Marc; Esteban, Esther; Villena, Mercedes; Vásquez, René; Dugoujon, Jean-Michel; Moral, Pedro (Annals of Human Genetics, 2012-07)
      Summary. The APOE/C1/C4/C2 gene cluster presents high relevance in lipid metabolism and, therefore, has important epidemiological implications. Here, we study for the first time the variation patterns of 25 polymorphisms ...

    • Aportes de la pletismografía corporal total al estudio de la adaptación respiratoria a la vida en altura 

      Villena, Mercedes; Vargas, Enrique (Universidad Mayor de San Andrés, 1990)
      Resumen. Los procesos de adaptación a la vida en la altura son permanentemente estudiados y el avance de la tecnología, permite conocer aspectos cada vez más novedosos. El objetivo del estudio de parámetros respiratorios ...

    • Autosomal and X chromosome alu insertions in Bolivian aymaras and quechuas : two languages and one genetic pool 

      Gayà-Vidal, Magdalena; Dugoujon, Jean-Michel; Esteban, Esther; Athanasiadis, Georgios; Rodríguez, Armando; Villena, Mercedes; Vásquez, René; Moral, Pedro (American Journal of Human Biology, 2010)
      Abstract. Thirty-two polymorphic Alu insertions (18 autosomal and 14 from the X chromosome) were studied in 192 individuals from two Amerindian populations of the Bolivian Altiplano (Aymara and Quechua speakers: the two ...

    • Aymara children are protected from high-altitude-induced pulmonary hypertension 

      Stuber, Thomas; Sartori, Claudio; Hutter, Damian; Salinas Salmón, Carlos E; Thalmann, Sebastien; Turini, Pierre; Jayet, Pierre-Yves; Villena, Mercedes; Scherrer, Urs; Allemann, Yves (High Altitude Medicine & Biology, 2005-02-22)
      Pulmonary hypertension is a hallmark of the adaptation to ambient lack of oxygen. This assumption is also thought to hold true for high-altitude native children, since invasive studies showed elevated pulmonary-artery pressure ...

    • Capacidad de difusión alvéolo capilar en niños residentes de altura 

      Vargas, Enrique; Villena, Mercedes; John, Beard; Haas, Jere; Cudkowicz, Leon (Aeronáutica de la Fuerza Aérea Boliviana, 1987)
      RESUMEN. La capacidad de difusión pulmonar (DLCO) para el monóxido de carbono fue determinada en 125 niños residentes de altura con edades que fluctuaban entre 4 y 6 años de edad. El estudio fue realizado en La Paz ...

    • Chronic mountain sickness and cor pulmonale La Paz-Bolivia (3,600-4,100 m) 

      Vargas P, Enrique; Villena, Mercedes; Salinas Salmón, Carlos E; Rodríguez, Armando; Téllez, Wilma; Bellido, Diva (Life on the Qinghai Tibetan plateau, 2007)
      Summary. Among the majority of inhabitants of La Paz-Bolivia (3,200-4,100 m.), the mild elevation seen in pulmonary artery pressure (PAP) has no clinical significance and is reversible on descent to lower altitude or with ...

    • Comparative aspects of high-altitude adaptation in human populations 

      Moore, Lorna G; Armaza, Fernando; Villena, Mercedes; Vargas, Enrique (Adv. Exp. Med. Biol., 2000)
      Abstract. The conditions and duration of high-altitude residence differ among high-altitude populations. The Tibetan Plateau is larger, more geographically remote, and appears to have been occupied for a longer period of ...

    • Depresión de la sensibilidad de los quimioreceptores y efectos sobre la hematosis en pacientes con poliglobulia patalógica de altura 

      Vargas P, Enrique; Villena, Mercedes; Guenard, H ([s.n.], 1986)

    • Determinación de distancia recorrida y variación de parámetros respiratorios y cardiovasculares, antes y después de la prueba de caminata de 6 minutos, en nativos y residentes permanentes de altura clinicamente sanos 

      Tirado, Karina; Villena, Mercedes (Rev Med (La Paz), 2014-01)
      Resumen. Objetivo:Determinar la distancia recorrida y la variación de parámetros respiratorios y cardiovasculares antes y después de la prueba de caminata de los 6 minutos (PC6M) en nativos y residentes permanentes de ...

    • Developmental components of resting ventilation among high - and low-altitude andean children and adults 

      Frisancho, A Roberto; Juliao, Patricia C; Barcelona, Verónica; Kudyba, Carmela E; Amayo, Glenda; Davenport, Grecia; Knowles, Alicia; Sánchez, Dani; Villena, Mercedes; Vargas, Enrique; Soria, Rudy (American Journal of Physical Anthroplogy, 1999)
      ABSTRACT. This paper evaluates the age-associated changes of resting ventilation of 115 high- and low-altitude Aymara subjects, of whom 61 were from the rural Aymara village of Ventilla situated at an average altitude ...

    • Developmental, genetic, and environmental components of aerobic capacity at high altitude 

      Frisancho, A Roberto; Frisancho, Hedy G; Milotich, Mark; Brutsaert, Tom; Albalak, Rachel; Spielvogel, Hilde; Villena, Mercedes; Vargas, Enrique; Soria, Rudy (American Journal of Physical Anthropology, 1995)
      Abstract. The aerobic capacity of 268 subjects (158 males and 110 females) was evaluated in La Paz, Bolivia situated at 3,750 m. The sample included 1) 39 high altitude rural natives (all male); 2) 67 high altitude urban ...

    • Efectos del tabaquismo en una población de altura (La Paz- Bolivia 3600 m.) 

      Spielvogel, Hilde; Antezana, Gerardo; Aparicio, Octavio; Bellido, Diva; Nallar, Nancy; Quintela, Aida; Peñaloza, Rosario; Tellez, Wilma; Vargas, Enrique; Villena, Mercedes (Revista Boliviana de Nefrología, 1990)

    • EPR spectroscopic evidence of iron-catalysed free radical formation in chronic mountain sickness : dietary causes and vascualr consequences 

      Bailey, Damian M; Culcasi, Marcel; Filipponi, Teresa; Brugniaux, Julien V; Stacy, Benjamin S; Marley, Chistopher J; Soria, Rodrigo; Rimoldi, Stefano F; Cerny, David; Rexhaj, Emrush; Pratali, Lorenza; Salinas Salmón, Carlos; Murillo Jáuregui, Carla; Villena, Mercedes; Villafuerte, Francisco; Rockenbauer, Antal; Pietri, Sylvia; Scherrer, Urs; Sartori, Claudio (Free Radical Biology and Medicine, 2022)
      Abstract Chronic mountain sickness (CMS) is a high-altitude (HA) maladaptation syndrome characterised by elevated systemic oxidative-nitrosative stress (OXNOS) due to a free radical-mediated reduction in vascular nitric ...

    • Estudio comparativo de la función ventricular derecha en participantes sanos y mal crónico de montaña 

      Murillo Jauregui, Carla; Romero, Catherine; Gonzales, Cristina; Alarcón, Ana María; Aguilar, Martha; Villena, Mercedes; Salinas, Carlos (COLEGIO MEDICO DE BOLIVIA, 2016-02)
      RESUMEN. La HP es un evento que es visto en la altitud. El mal crónico de montaña es un síndrome de pérdida gradual de la capacidad de adaptación a la altura, con eritrocitosis excesiva, (Hb hombres > 21 gr/dl), severa ...

    • Estudio en doble ciego del efecto de la almitrina sobre los enfermos portadores de eritrocitosis - patológica de altura 

      Villena, Mercedes; Vargas, Enrique; Guenard, Hervé; Nallar, Nancy; Téllez, Wilma; Spielvogel, Hilde (Instituto Boliviano de Biología de Altura, 1987)
      Resumen. La eritrocitosis patológica de altura (EPA) es una afección caracterizada por una disminución importante de la sensibilidad a la hipoxia y a la hipercapnea que conduce a una hipoxemia con eritrocitosis excesiva ...

    • Exaggerated exercise-induced pulmonary hypertension causes lung water accumulation and right ventricular dysfunction in patients with chronic mountain sickness 

      Pratali, Lorenza; Rimoldi, Stefano F; Rexhaj, Emrush; Salinas Salmón, Carlos E; Villena, Mercedes; Sicari, Rosa; Picano, Eugenio; Scherrer, Urs; Allemann, Yves; Sartori, Claudio (High Altitude Medicine & Biology, 2010-08-08)

    • Exaggerated pulmonary hypertension and right ventricular dysfunction in high-altitude dwellers with patent foramen ovale 

      Brenner, Roman; Pratali, Lorenza; Rimoldi, Stefano F; Murillo Jauregui,Carla Ximena; Soria, Rodrigo; Rexhaj, Emrush; Salinas Salmón, Carlos; Villena, Mercedes; Romero, Catherine; Sartori, Claudio; Allemann, Yves; Scherrer, Urs (Chest, 2015)
      There is considerable interindividual variability in pulmonary artery pressure among high-altitude (HA) dwellers, but the underlying mechanism is not known. At low altitude, a patent foramen ovale (PFO) is present in about ...