Listar Producción científica por autor "Vargas, Enrique"
Mostrando ítems 41-60 de 85
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Human physiological adaptation to pregnancy : inter- and intrspecific perspectives
Rockwell, Christie; Vargas, Enrique; Moore, Lorna G (American Journal of Human Biology, 2003)Abstract. Reproductive success requires successful maternal physiological adaptation to pregnancy. An interspecific perspective reveals that the human species has modified features of our haplorhine heritage affecting ... -
Increased incidence of preeclampsia lowers birth weight and increases intrauterine mortality at high altitude
Armaza, Fernando; Vargas, Enrique; Bohrt, Roberto; Moore, Lorna G (High Altitude Medicine & Biology, 2001) -
Inhibition of peroxisome proliferator gamma (PPARɣ) : a potential link between chronic maternal hypoxia and impaired fetal growth
Julian, Colleen Glyde; Yang, Ivana; Vargas, Enrique; Pedersen, Brent S; Moore, Lorna G; Schwartz, David (Journal of Women's Health, 2013)Background and Objective: Chronic maternal hypoxia impairs fetal growth and increases the incidence of intrauterine growth restriction (IUGR). To identify the mechanisms underlying these hypoxia-related effects, we evaluated ... -
Inhibition of peroxisome proliferator-activated receptor ɣ : a potential link between chronic maternal hypoxia and impaired fetal growth
Julian, Colleen Glyde; Yang, Ivana V; Browne, Vaughn A.; Vargas, Enrique; Rodríguez, Carmelo; Pedersen, Brent S; Moore, Lorna G; Schwartz, David A (FASEB Journal, 2014)Abstract. Chronic exposure to hypoxia raises the risk of pregnancy disorders characterized by maternal vascular dysfunction and diminished fetal growth. In an effort to identify novel pathways for these hypoxiarelated ... -
Instituto Boliviano de Biología de Altura, razones de su creación y funcionamiento
Vargas, Enrique (Instituto Boliviano de Biología de Altura, 1988)Pocos territorios situados en regiones elevadas en el mundo son tan accesibles, como los Andes, al estudio de poblaciones residentes en permanencia. Bolivia situada en el corazón de América tiene en La Paz, y otros centros ... -
Intrauterine growth restriction, preeclampsia, and intrauterine mortality at high altitude in Bolivia
Keyes, LE; Armaza, Fernando; Niermeyer, Susan; Vargas, Enrique; Young, David A; Moore, Lorna G (PEDIATRIC RESEARCH, 2003-02-18)Abstract. Infant mortality and stillbirth rates in Bolivia are high and birth weights are low compared with other South American countries. Most Bolivians live at altitudes of 2500 m or higher. We sought to determine the ... -
La investigación médica francesa y el Instituto Boliviano de Biología de Altura
Vargas, Enrique (CRONICA AGUDA, 1988-07)Hasta hace 25 años, nuestro país estuvo ausente del grupo, científico mundial que estudia los problemas relacionados con la hipoxia de altura. En ocasión de la visita del Presidente francés, Charles de Gaulle, se firmó un ... -
Índice de resistencia vascular arterial en la madre y el feto durante el embarazo en grandes alturas (3600 m) vs. niveles bajos de altura (300 m)
Postigo, Lucrecia; Heredia, Gladis; Rodríguez, Carmelo; Toledo, Lilian; Torricos, Tatiana; Vargas, Enrique; Zamudio, Stacy (Revista de la Sociedad Boliviana de Radiología, 2007)Resumen. Objetivo: Determinar los índices de resistencia de las arterias uterinas en las madres, umbilical y cerebral media en los bebés de grandes alturas, en comparación a pacientes que habitan alturas bajas reflejados ... -
Lowland origin women raised at high altitude are not protected against lower uteroplacental O2 delivery during pregnancy or reduced birth weight
Julian, Colleen Glyde; Hageman, Jennifer L; Wilson, Megan J; Vargas, Enrique; Moore, Lorna G (American Journal of Human Biology, 2011-04-27)Objective. Maternal physiologic responses to pregnancy promoting fetal oxygen and nutrient delivery are important determinants of reproductive success. Incomplete physiologic compensation for reduced oxygen availability ... -
Maternal adaptation to high-altitude pregnancy : an experiment of nature-a review
Moore, Lorna G; Shriver, M; Bemis, L; Hickler, B; Wilson, M; Brutsaert, T; Parra, E; Vargas, Enrique (Placenta, 2004)A long and productive history of studies at high altitude has demonstrated that chronic hypoxia plays a key role in the aetiology of intrauterine growth restriction (IUGR) and pre-eclampsia. Susceptibility to altitude-associated ... -
Maternal and fetoplacental hypoxia do not alter circulating angiogenec growth effectors during human pregnancy
Zamudio, Stacy; Borges, Marcus; Echalar, Lourdes; Kovalenko, Olga; Vargas, Enrique; Torricos, Tatiana; Al Khan, Abdulla; Álvarez, Manuel; Illsley, Nicholas P (Biol Reprod., 2014-02-27)Abstract. One causal model of preeclampsia (PE) postulates that placental hypoxia alters the production of angiogenic growth effectors (AGEs), causing an imbalance leading to maternal endothelial cell dysfunction. We ... -
Maternal oxygen delivery is not related to altitude- and ancestry-associated differences in human fetal growth
Zamudio, Stacy; Postigo, Lucrecia; Illsley, Nicholas P; Rodríguez, Carmelo; Heredia, Gladys; Brimacombe, Michael; Echalar, Lourdes; Torricos, Tatiana; Téllez, Wilma; Maldonado, Iván; Balanza Erquicia, Elfride; Álvarez, Tatiana; Ameller, Julio; Vargas, Enrique (J Physiol, 2007-09-16)Fetal growth is reduced at high altitude, but the decrease is less among long-resident populations. We hypothesized that greater maternal uteroplacental O2 delivery would explain increased fetal growth in Andean natives ... -
Maternal PRKAA1 and EDNRA genotypes are associated with birth weight, and PRKAA1 with uterine artery diameter and metabolic homeostasis at high altitude
Bigham, Abigail W; Julian, Colleen Glyde; Wilson, Megan J; Vargas, Enrique; Browne, Vaughn A.; Shriver, Mark D; Moore, Lorna G (Physiol Genomics, 2014-07-14)Low birth weight and intrauterine growth restriction (IUGR) increase the risk of mortality and morbidity during the perinatal period as well as in adulthood. Environmental and genetic factors contribute to IUGR, but the ... -
Mecánica ventilatoria en pacientes con eritrocitosis de altura
Villena, Mercedes; Vargas, Enrique; Villena de Rodriguez, Nancy; Beaulieu, Pierre (Instituto Boliviano de Biología de Altura, 1979)Se trata de un análisis de los aspectos generales que intervienen en la mecánica ventilatoria así como los factores que determinan sus variaciones patológicas. Fueron estudiados 138 pacientes poliglobúlicos de los cuales ... -
Metahemoglobinemia de altura. Metahemoglobina = reverva de hemoglobina
Arnaud, Jacques; Gutiérrez, Nancy; Vargas, Enrique; Tellez, Wilma (Revista Sociedad Latinoamericana de Hematología, 1979)Resumen. En las grandes alturas, el eritrocito humano sometido a una hipoxia permanente, es el sitio de modificaciones metabólicas entre las cuales la metahemoglobinemia ha retenido nuestra atención. En el presente trabajo ... -
Neonatal oxygenation, pulmonary hypertension, and evolutionary adaptation to high altitutde (2013 Grover Conference series)
Niermeyer, Susan; Andrade-M, Mario Patricio; Vargas, Enrique; Moore, Lorna G (Pulm Circ, 2015-03)Abstract. Andeans and Tibetans have less altitude reduction in birth weight than do shorter-resident groups, but only Tibetans are protected from pulmonary hypertension and chronic mountain sickness (CMS). We hypothesized ... -
Patrones reproductivos en la altura : hipoxia o regulación cultural
Crognier, Emile; Villena, Mercedes; Vargas, Enrique (Rev. Arg. Antrop. Biol., 2001) -
Percent of oxygen saturation of arterial hemoglobin among Bolivian aymara at 3,900-4000 m
Beall, Cynthia M; Almasy, Laura A; Blangero, John; Williams-Blangero, Sarah; Brittenham, Gary M; Strohl, Kingman P; Decker, Michael J; Vargas, Enrique; Villena, Mercedes; Soria, Rudy; Alarcón, Ana María; Gonzales, Cristina (American Journal of Physical Anthroplogy, 1999)ABSTRACT. A range of variation in percent of oxygen saturation of arterial hemoglobin (SaO2) among healthy individuals at a given high altitude indicates differences in physiological hypoxemia despite uniform ambient ... -
Perinatal hypoxia increases susceptibility to high-altitude polycythemia and attendant pulmonary vascular dysfunction
Julian, Colleen Glyde; Gonzales, Marcelino; Rodríguez, Armando; Bellido, Diva; Salinas Salmón, Carlos; Ladenburger, Anne; Reardon, Lindsay; Vargas, Enrique; Moore, Lorna G (Am J Physiol Heart Circ Physiol, 2015-04-27)Perinatal hypoxia increases susceptibility to high-altitude polycythemia and attendant pulmonary vascular dysfunction. Am J Physiol Heart Circ Physiol 309: H565–H573, 2015. First published June 19, 2015; doi:10.1152/a ... -
Perinatal origins of chronic mountain sickness : the role of perinatal hypoxia in the development of CMS
Vargas, Enrique; Julian, Colleen Glyde; Salinas Salmón, Carlos E; Dávila, Daniela; Rodríguez, Armando; Gonzales, Marcelino; Moore, Lorna G (Meeting VII Congress World Medicine and Physiology High Altitude, 2011)