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Latin Americans show wide-spread converso ancestry and imprint of local native ancestry on physical appearance
(Nature communications, 2018)
Abstract.
Historical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. Using novel haplotype-based ...
Apolipoprotein E/C1/C4/C2 gene cluster diversity in two native andean populations : Aymaras and Quechuas
(Annals of Human Genetics, 2012-07)
Summary.
The APOE/C1/C4/C2 gene cluster presents high relevance in lipid metabolism and, therefore, has important epidemiological implications. Here, we study for the first time the variation patterns of 25 polymorphisms ...
Genetic variations in the TP53 pathway in native americans strongly suggest adaptation to the high altitudes of the andes
(PLOS One, 2015-09-18)
Abstract.
The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and
LIF, rs929271) were studied in a total of ...
High-altitude hypoxia and echocardiographic indices of pulmonary hypertension in male and female chickens at adulthood
(Circulation Journal, 2014-06)
Background: By combining the chick embryo model with incubation at high altitude (HA), the effects of chronic hypoxia on fetal growth, fetal cardiac and aortic wall remodeling and systemic arterial blood pressure at adulthood ...
Determinación de distancia recorrida y variación de parámetros respiratorios y cardiovasculares, antes y después de la prueba de caminata de 6 minutos, en nativos y residentes permanentes de altura clinicamente sanos
(Rev Med (La Paz), 2014-01)
Resumen.
Objetivo:Determinar la distancia recorrida y la variación de parámetros respiratorios
y cardiovasculares antes y después de la prueba de caminata de los 6 minutos
(PC6M) en nativos y residentes permanentes de ...
Ancient human genomes suggest three ancestral populations for present-day Europeans
(Nature, 2014-09-18)
We sequenced the genomes of a 7,000-year-old farmer from Germanyandeight 8,000-year-oldhunter-gatherersfromLuxembourg and Sweden. We analysed these and other ancient genomes1–4 with 2,345contemporaryhumanstoshowthatmostp ...
Comparative aspects of high-altitude adaptation in human populations
(Adv. Exp. Med. Biol., 2000)
Abstract.
The conditions and duration of high-altitude residence differ among high-altitude populations. The Tibetan Plateau is larger, more geographically remote, and appears to have been occupied for a longer period of ...
Excessive polycythemia occurs in young high-altitude (3600 m) residents in the absence o lung disease
(Health & height proceeding, 2002)
Summary.
Chronic mountain sickness is present in about 8% of the male population of La Paz. Our question was whether its principal diagnostic sign, excessive polycythemia (EP) without lung disease could be found already ...
Repercusión funcional respiratoria de sobrepeso y obesidad en habitantes de gran altura
(COLEGIO MEDICO DE BOLIVIA, 2016-02)
RESUMEN.
A nivel mundial se ha visto un aumento del sobrepeso y obesidad y Bolivia no es la excepción, en la ciudad de La Paz existe 19,190 casos, en Cochabamba existe 12,231, y en Santa Cruz hay 7,731 casos, según datos ...