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Inhibition of peroxisome proliferator gamma (PPARɣ) : a potential link between chronic maternal hypoxia and impaired fetal growth
(Journal of Women's Health, 2013)
Background and Objective: Chronic maternal hypoxia impairs
fetal growth and increases the incidence of intrauterine growth restriction (IUGR). To identify the mechanisms underlying these hypoxia-related effects, we evaluated ...
Pulmonary nitric oxide in mountain dwellers
(NATURE, 2001-11-22)
Nitric oxide is synthesized in the lungs to help regulate blood flow, and its levels have been found to drop in
species native to low altitudes, including
humans, upon acute exposure to reduced
oxygen concentration1–3. ...
Uterine artery blood flow during pregnancy in high-altitude aymara women
(High Altitude Medicine & Biology, 2003-02-19)
Background.
Birth weight falls with increasing altitude as the result of
intrauterine growth restriction (IUGR) likely due, in turn, to lower uterine artery (UtA) blood flow. The altitude-associated birth weight decline
is ...
Excessive polycythemia occurs in young high-altitude (3600 M) residents in the absence of lung disease
(High Altitude Medicine & Biology, 2002-04-18)
Objective: Chronic Mountain Sickness occurs in , 8% of the La Paz
population. We asked whether its primary diagnostic sign, excessive polycythemia (EP), occurred in youngeraged persons
without lung disease. Methods: ...
High-altitude ancestry protects against IUGR and reductions in birth weight associated with high altitude and preeclampsia
(High Altitude Medicine & Biology, 2005-02-22)
Background.
Observations consistently demonstrate diminished birth weight [BW] with ascending altitude;
however population comparisons reveal the extent of BW
reduction depends, in part, upon high-altitude ancestry.
...
Protective effect of female sex hormones against pulmonary hypertension in Bolivian high altitude natives
(High Altitude Medicine & Biology, 2003-02-19)
There is abundant evidence that female sex hormones have protective effects in the systemic circulation in both animals and humans,
but little is known regarding their role in the regulation of the pulmonary circulation. ...
Do anti-angiogenic or angiogenic factors contribute to the protection of birth weight at high altitude afforded by andean ancestry?
(Reprod Sci., 2010-09)
Abstract.
Objective: This prospective study was designed to determine whether variation in angiogenic
(placental growth factor [PlGF]) and/or anti-angiogenic (soluble fms-like tyrosine kinase [sFlt-1])
factors contribute ...
Perinatal origins of chronic mountain sickness : the role of perinatal hypoxia in the development of CMS
(Meeting VII Congress World Medicine and Physiology High Altitude, 2011)
Rendimiento de futbolistas profesionales aclimatados y no aclimatados a la altura, a 3600 metros
(PubliCE, 2003-01-05)
Resumen.
Los partidos del Fútbol Europeo son frecuentemente jugados a nivel internacional en regiones montañosas de Sudamérica. En este estudio, fueron medidas las respuestas del ejercicio durante una ergometría en ciclo ...
Maternal adaptation to high-altitude pregnancy : an experiment of nature-a review
(Placenta, 2004)
A long and productive history of studies at high altitude has demonstrated that chronic hypoxia plays a key role in the aetiology of intrauterine growth restriction (IUGR) and pre-eclampsia. Susceptibility to altitude-associated ...