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Do cytokines contribute to the andean-associated protection from reduced fetal growth at high altitude?
(Reproductive Sciences, 2011)
Abstract.
Pro- versus anti-inflammatory cytokine balance is important for successful pregnancy. Chronic hypoxia alters cytokine levels and increases the frequency of fetal growth restriction (FGR). Multigenerational Andean ...
Systemic vascular dysfunction in patients with chronic mountain sickness
(CHEST, 2012-01-01)
Background: Chronic mountain sickness (CMS) is a major public health problem characterized by
exaggerated hypoxemia and erythrocytosis. In more advanced stages, patients with CMS often
present with functional and structural ...
Comparative responses of arterial oxygen saturation and heart rate durign postnatal development in rats living at high and low altitude
(Actas Club Recherché Clinique de Quebec, 2011)
We used pulse oximetry to measure arterial oxygen saturation (SpO2) and heart rate (HR)
in 4 and 14 day-old rats raised at HA (La Paz, Bolivia, 3,600 m / 12,000ft) or at sea level
(SL, Québec, Canada). SpO2 and HR were ...
Overview of how ecosystem changes can affect human health
(ELSEVIER, 2011)
Ecosystem changes can affect human health in several forms, most of them indirectly. Degraded ecosystems can affect water quality and availability, and cause a decrease in food production, climatic instability, poor ...
Reconstructing native American population history
(NATURE, 2012-08-16)
The peopling of the Americas has been the subject of extensive
genetic, archaeological and linguistic research; however, central
questions remain unresolved1–5. One contentious issue is whether
the settlement occurred ...
Exercise induces rapid interstitial lung water accumulation in patients with chronic mountain sickness
(CHEST, 2012-04-04)
Background: Chronic mountain sickness (CMS) is a major public health problem in mountainous
regions of the world. In its more advanced stages, exercise intolerance is often found, but the
underlying mechanism is not ...
Potential role for elevated maternal enzymatic antioxidant status in Andean protection against altitude-associated SGA
(The Journal of Maternal-Fetal and Neonatal Medicine, 2012)
Oxidative stress has been implicated in the uteroplacental
ischemia characteristic of preeclampsia and small-for-gestational-age (SGA) birth, both of which are more common at high
(>2500 m) vs low altitude. Since Andeans ...
Changes in blood gas transport of altitude native soccer players near sea-level and sea-level native soccer players at altitude (ISA3600)
(Br J Sports Med, 2013-09-03)
Abstract.
Objectives The optimal strategy for soccer teams
playing at altitude is not known, that is, ‘fly-in, fly-out’
versus short-term acclimatisation. Here, we document
changes in blood gas and vascular volumes of ...
Role of cytokines in altitude-associated preeclampsia
(Pregnancy Hypertens, 2012-01)
Abstract.
Background: Preeclampsia (PE) is more common at high than low altitude and contributes
to the altitude-related decline in birth weight. Since inflammatory markers are implicated
in PE, we asked if such markers ...
Andean and Tibetan patterns of adaptation to high altitude
(American Journal of Human Biology, 2013-01-24)
Objectives: High-altitude hypoxia, or decreased oxygen levels caused by low barometric pressure, challenges the
ability of humans to live and reproduce. Despite these challenges, human populations have lived on the Andean ...