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Seasonal and circadian variation in salivary testosterone in rural Bolivian men
(American Journal of Human Biology, 2009-02-19)
Abstract.
Testosterone (T) plays a key role in the increase and maintenance of muscle mass and bone density in
adult men. Life history theory predicts that environmental stress may prompt a reallocation of such investments ...
Greater uterine artery blood flow during pregnancy in multigenerational (Andean) than shorter-term (European) high-altitude residents
(Am J Physiol Regul Integr Comp Physiol, 2007)
Multigenerational (Andean) compared with shorter-term (European) high-altitude
residents exhibit less hypoxia-associated reductions in birth
weight. Because differences in arterial O2 content are not responsible,
we ...
Higher estrogen levels during pregnancy in Andean than European residents of high altitude suggest differences in aromatase activity
(J Clin Endocrinol Metab, 2014-08)
Context: Uteroplacental hypoxia has been reported to lower estrogen levels in preeclampsia as the
result of reduced aromatase activity.
Objective: We asked whether the chronic hypoxia of residence at high altitude in the ...
A genomewide admixture mapping panel for hispanic/latino populations
(The American Journal of Human Genetics, 2007-06)
Admixture mapping (AM) is a promising method for the identification of genetic risk factors for complex traits and
diseases showing prevalence differences among populations. Efficient application of this method requires the ...
Does chronic mountain sickness (CMS) have perinatal origins?
(Respiratory Physiology & Neurobiology, 2007-06-29)
Abstract.
Chronic mountain sickness (CMS) occurs in 10% of male high-altitude residents. It is characterized by hypoventilation and hypoxemia but its underlying cause remains unknown. We hypothesized that CMS' origins ...
Evidence that parent-of-origin affects birth-weight reductions at high altitude
(American Journal of Human Biology, 2008-02-19)
Abstract.
Hypoxia exerts a profound depressant effect on fetal growth, lowering birth weight, and raising mortality risk. Multigenerational high-altitude populations are relatively protected from this birth-weight decline, ...
Maternal and fetoplacental hypoxia do not alter circulating angiogenec growth effectors during human pregnancy
(Biol Reprod., 2014-02-27)
Abstract.
One causal model of preeclampsia (PE) postulates that
placental hypoxia alters the production of angiogenic growth
effectors (AGEs), causing an imbalance leading to maternal
endothelial cell dysfunction. We ...
Consensus statement on chronic and subacute high altitude diseases
(High Altitude Medicine & Biology, 2005)
ABSTRACT.
This is an international consensus statement of an ad hoc committee formed by the In
ternational Society for Mountain Medicine (ISMM) at the VI World Congress on Mountain Med
icine and High Altitude Physiology ...
The effects of smoking on a high altitude population. (La Paz, Bolivia, 3600m or 12,200ft)
(Tobacco and Health, 1990)
Barometric pressure (PB) decreases with increasing a altitude. Since oxygen concentration is about 21% in the air of
the whole atmosphere, its partial pressure is also 21% of PB. At the altitude of La Paz (3600)m or ...
Índice de resistencia vascular arterial en la madre y el feto durante el embarazo en grandes alturas (3600 m) vs. niveles bajos de altura (300 m)
(Revista de la Sociedad Boliviana de Radiología, 2007)
Resumen.
Objetivo: Determinar los índices de resistencia de las arterias uterinas en las madres, umbilical y cerebral media en los bebés de grandes alturas, en comparación a pacientes que habitan alturas bajas reflejados ...