Listar Producción científica por autor "Joseph, Vincent"
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Comparative responses of arterial oxygen saturation and heart rate durign postnatal development in rats living at high and low altitude
Lemoine, Alejandra Jochmans; Villalpando, Gabriela; Gonzales, Marcelino; Soria, Rudy; Joseph, Vincent (Actas Club Recherché Clinique de Quebec, 2011)We used pulse oximetry to measure arterial oxygen saturation (SpO2) and heart rate (HR) in 4 and 14 day-old rats raised at HA (La Paz, Bolivia, 3,600 m / 12,000ft) or at sea level (SL, Québec, Canada). SpO2 and HR were ... -
Divergent mitochondrial antioxidant activities and lung alveolar architecture in the lungs of rats and mice at high altitude
Jochmans-Lemoine, Alexandra; Revollo, Susana; Villalpando, Gabriela; Valverde, Ibana; Gonzales, Marcelino; Laouafa, Sofien; Soliz, Jorge; Joseph, Vincent (Frontiers in Physiology, 2018)Abstract. Compared with mice, adult rats living at 3,600 m above sea level (SL—La Paz, Bolivia) have high hematocrit, signs of pulmonary hypertension, and low lung volume with reduced alveolar surface area. This phenotype ... -
Divergent physiological responses in laboratory rats and mice raised at high altitude
Jochmans-Lemoine, Alejandra; Villalpando, Gabriela; Gonzales, Marcelino; Valverde, Ibana; Soria, Rudy; Joseph, Vincent (The Journal of Experimental Biology, 2015-01-29)Abstract. Ecological studies show that mice can be found at high altitude (HA – up to 4000 m) while rats are absent at these altitudes, and there are no data to explain this discrepancy. We used adult laboratory rats ... -
Dopaminergic metabolism in carotid bodies and high altitude acclimatization in female rats
Joseph, Vincent; Soliz, Jorge; Soria, Rudy; Pequignot, Jacqueline; Favier, Roland; Spielvogel, Hilde; Pequignot, Jean Marc (Am J Physiol Relulatory, 2002-04)We tested the hypothesis that ovarian steroids stimulate breathing through a dopaminergic mechanism in the carotid bodies (CB). In ovariectomized female rats raised at sea level, domperidone, a peripheral D2 receptor ... -
Effects of prenatal hypoxia on hematological and respiratory acclimatization to high altitude in rats
Lemoine, Alejandra Jochmans; Lumbroso, Delphine; Villalpando, Gabriela; Gonzales, Marcelino; Soria, Rudy; Joseph, Vincent (Actas Club Recherché Clinique de Quebec, 2011)We tested the hypothesis that prenatal hypoxia have long-term consequences on physiological acclimatization to high altitude in rats. Male and female high-altitude rats (3600m, La Paz, Bolivia) were exposed to normal ... -
Erythropoietin and caffeine exert similar protective impact against neonatal intermittent hypoxia : apnea of prematurity and sex dimorphism
Laouafa, Sofien; Iturri, Pablo; Arias-Reyes, Christian; Marcouiller, François; Gonzales, Marcelino; Joseph, Vincent; Bairam, Aida; Soliz, Jorge (Experimental Neurology, 2019)Abstract. Apnea of prematurity (AoP) is associated with severe and repeated episodes of arterial oxygen desaturation (intermittent hypoxia - IH), which in turn increases the number of apneas. So far, there is no data ... -
Hematocrit and hemoglobin levels at adulthood are determined by neonatal hypoxic exposure in rats living at high altitude
Lumbroso, Delphine; Villalpando, Gabriela; Gonzales, Marcelino; Soria Sánchez, Rudy; Joseph, Vincent (High Altitude Medicine & Biology, 2010-08-08)Introduction: In previous work performed at sea level we reported that exposure to neonatal hypoxia impairs ventilatory and hematological responses to chronic hypoxia later in life. These findings supported the hypothesis ... -
Life-long consequences of postnatal normoxia exposure in rats raised at high altitude
Lumbroso, Delphine; Lemoine, Alexandra; Gonzales, Marcelino; Villalpando, Gabriela; Seaborn, Tommy; Joseph, Vincent (J Appl Physiol., 2012)Abstract. We tested the hypothesis that exposure of high-altitude (HA) rats to a period of postnatal normoxia has long-term consequences on the ventilatory and hematological acclimatization in adults. Male and female HA ... -
Life-long consequences of postnatal normoxia exposure in rats raised at high altitude
Lumbroso, Delphine; Lemoine, Alejandra Jochmans; Gonzales, Marcelino; Villalpando, Gabriela; Seaborn, Tommy; Joseph, Vincent (J Appl Physiol, 2012-03-13)We tested the hypothesis that exposure of high-altitude (HA) rats to a period of postnatal normoxia has long-term consequences on the ventilatory and hematological acclimatization in adults. Male and female HA rats (3,600 ... -
Programmation prénatale de l'acclimatation hématologique et respiratoire chez des rats de haute altitude
Lemoine, Alejandra Jochmans; Lumbroso, Delphine; Villalpando, Gabriela; Gonzales, Marcelino; Soria, Rudy; Joseph, Vincent (Actas Club Recherché Clinique de Quebec, 2011)Nous avons testé l’hypothèse selon laquelle l’hypoxie prénatale chez le rat aurait des conséquences à long terme sur l’acclimatation physiologique à la haute altitude. Des rats vivant en haute altitude (3600m, La Paz, ...