• Aymara children are protected from high-altitude-induced pulmonary hypertension 

      Stuber, Thomas; Sartori, Claudio; Hutter, Damian; Salinas Salmón, Carlos E; Thalmann, Sebastien; Turini, Pierre; Jayet, Pierre-Yves; Villena, Mercedes; Scherrer, Urs; Allemann, Yves (High Altitude Medicine & Biology, 2005-02-22)
      Pulmonary hypertension is a hallmark of the adaptation to ambient lack of oxygen. This assumption is also thought to hold true for high-altitude native children, since invasive studies showed elevated pulmonary-artery pressure ...
    • Exercise induces rapid interstitial lung water accumulation in patients with chronic mountain sickness 

      Pratali, Lorenza; Rimoldi, Stefano F; Rexhaj, Emrush; Hutter, Damian; Faita, Francesco; Salinas Salmón, Carlos E; Villena, Mercedes; Sicari, Rosa; Picano, Eugenio; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (CHEST, 2012-04-04)
      Background: Chronic mountain sickness (CMS) is a major public health problem in mountainous regions of the world. In its more advanced stages, exercise intolerance is often found, but the underlying mechanism is not ...
    • Offspring of preeclamptic mothers are predisposed to hypoxic pulmonary hypertension 

      Sartori, Claudio; Jayet, Pierre-Yves; Thalmann, Sebastien; Stuber, Thomas; Hutter, Damian; Salinas Salmón, Carlos E; Cucchia, Celine; Rodriguez, Armando; Riveros, Loyola; Spielvogel, Hilde; Allemann, Yves; Villena, Mercedes; Scherrer, Urs (High Altitude Medicine & Biology, 2005-02-22)
      Adverse events in utero may predispose to cardiovascular disease in adulthood. In preeclampsia, the diseased placenta releases circulating vasculotoxic factors that cause maternal endothelial dysfunction. These factors ...
    • Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia 

      Jayet, Pierre-Yves; Rimoldi, Stefano F; Stuber, Thomas; Salinas Salmón, Carlos E; Hutter, Damian; Rexhaj, Emrush; Thalmann, Sébastien; Schwab, Marcos; Turini, Pierre; Sartori-Cucchia, Céline; Nicod, Pascal; Villena, Mercedes; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (Circulation, 2010-07-19)
      Background—Adverse events in utero may predispose to cardiovascular disease in adulthood. The underlying mechanisms are unknown. During preeclampsia, vasculotoxic factors are released into the maternal circulation by the ...
    • Respiratory nitric oxide and pulmonary artery pressure in children of aymara and european ancestry at high altitude* 

      Stuber, Thomas; Sartori, Claudio; Salinas Salmón, Carlos E; Hutter, Damian; Thalmann, Sébastien; Turini, Pierre; Jayet, Pierre-Yves; Schwab, Marcos; Sartori-Cucchia, Céline; Villena, Mercedes; Scherrer, Urs; Allemann, Yves (CHEST, 2008-11-07)
      Invasive studies suggest that healthy children living at high altitude display pulmonary hypertension, but the data to support this assumption are sparse. Nitric oxide (NO) synthesized by the respiratory epithelium regulates ...
    • Response to letters regarding article, "Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia" 

      Rimoldi, Stefano F; Jayet, Pierre-Yves; Rexhaj, Emrush; Thalmann, Sébastien; Schwab, Marcos; Turini, Pierre; Sartori-Cucchia, Céline; Nicod, Pascal; Scherrer, Urs; Sartori, Claudio; Hutter, Damian; Stuber, Thomas; Allemann, Yves; Salinas Salmón, Carlos E; Villena, Mercedes (Circulation, 2011)
      We thank Lazdam et al and Yuan et al for their interesting comments on our study.1 Lazdam et al point out that in our study, birth weight in offspring of mothers with preeclampsia was significantly lower than in controls, ...
    • RV contractility and exercise-induced pulmonary hypertension in chronic mountain sickness : a stress echocardiographic and tissue doppler imaging study 

      Pratali, Lorenza; Allemann, Yves; Rimoldi, Stefano F; Faita, Francesco; Hutter, Damian; Rexhaj, Emrush; Brenner, Roman; Bailey, Damian M; Sartori, Claudio; Salinas Salmón, Carlos E; Villena, Mercedes; Scherrer, Urs; Picano, Eugenio; Sicari, Rosa (ELSEVIER, 2013-12)
      Objectives. The aim of this study was to evaluate right ventricular (RV) and left ventricular function and pulmonary circulation in chronic mountain sickness (CMS) patients with rest and stress echocardiography compared ...
    • Systemic vascular dysfunction in patients with chronic mountain sickness 

      Rimoldi, Stefano F; Rexhaj, Emrush; Pratali, Lorenza; Bailey, Damian; Hutter, Damian; Faita, Francesco; Salinas Salmón, Carlos E; Villena, Mercedes; Nicod, Pascal; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (CHEST, 2012-01-01)
      Background: Chronic mountain sickness (CMS) is a major public health problem characterized by exaggerated hypoxemia and erythrocytosis. In more advanced stages, patients with CMS often present with functional and structural ...