Listar Producción científica por autor "Fournet, Alain"

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    • 2-Substituted quinoline alkaloids as potential antileishmanial drugs 

      Fournet, Alain; Angelo Barrios, Alcira; Muñoz, Victoria; Hocquemiller, Reynald; Cavé, André; Bruneton, Jean (Antimicrobial Agents and Chemotherapy, 1993-04)
      Abstract. Ten 2-substituted quinoline alkaloids isolated from a plant used for treatment of New World cutaneous leishmaniasis have antileishmanial in vitro activities against the extracellular forms of Leishmania spp. ...

    • Antiprotozoal activity of aporphine alkaloids isolated from Unonopsis buchtienii (Annonaceae) 

      Waechter, Anne-Isabelle; Cavé, André; Hocquemiller, Reynald; Bories, Christian; Muñoz, Victoria; Fournet, Alain (PHYTOTHERAPY RESERARCH, 1999)
      On a preliminary screening, substantial leishmanicidal activity was observed for the petroleum ether and alkaloidal extracts of the stem bark of Unonopsis buchtienii, the alkaloids and sterols isolated from these were ...

    • Antiprotozoal activity of dehydrozaluzanin C, a sesquiterpene lactone isolated from munnozia maronii (Asteraceae) 

      Fournet, Alain; Muñoz, Victoria; Roblot, François; Hocquemiller, Reynald; Cavé, André (PHYTOTHERAPY RESEARCH, 1993)
      The petrolelum ether extract of the leaves of Munnozia maronii was found to inhibit in vitro the growth of promastigote forms of Leishmania and epimastigote forms of Trypanosoma cruzi with and IC of 25 µg/mL. Activity-guided ...

    • Aryl-2 et alkyl-2 quinoléines nouvelles isolées d'une rutacée bolivienne: Galipea longiflora 

      Fournet, Alain; Vagneur, Beatrice; Richomme, Pascal; Bruneton, Jean (Can. J. Chem., 1989)
      Cinq aryl-2 et alkyl-2 quinoléines nouvelles ont été isolées des écorces de tiges de Galipea longiflora Krause (Rutacées) : la phényl-2 quinoléine 1, la (méthylènedioxy-3', 4') phénéthyl-2 quinoléine 2, la (diméthoxy-3',4') ...

    • Biological and chemical studies of Pera benensis, a Bolivian plant used in folk medicine as a treatment of cutaneous leishmaniasis 

      Fournet, Alain; Angelo, Alcira; Muñoz, Victoria; Roblot, François; Hocquemiller, Reynald; Cavé, André (Journal of Ethnopharmacology, 1992)
      The stem barks of Pera benensis are employed by the Chimane Indians in the Bolivian Amazonia as treatment of cutaneous leishmaniasis caused by the protozoan Leishmania braziliensis. The chloroform extracts containing ...

    • Bis-benzylisoquinoline alkaloids from abuta pahni 

      Duté, Pascale; Weber, Jean-Frédéric; Fournet, Alain; Cavé, Adrien; Bruneton, Jean-Michel (Phytochemistry; Instituto Boliviano de Biología de Altura. Anuario 1987, 1987)
      Abstract. From the stems of Abicta pcthrii, eight isoquinoline alkaloids were isolated and identified by spectroscopic methods and chemical correlations. Three of the bis-benzylisoquinoline alkaloids are new and were ...

    • Effect of some bisbenzylisoquinoline alkaloids on American Leishmania sp. in BALB/c mice 

      Fournet, Alain; Angelo Barrios, Alcira; Muñoz, Victoria; Hocquemiller, Reynald; Cavé, André (PHYTOTHERAPY RESEARCH, 1993)
      Abstract. Four bisbenzylisoquinoline alkaloids, antioquine, berbamine, gyrocarpine and isotetrandrine were tested in BALB/c mice infected with Leishmania amazonensis (IFLA/BR/67/PH8 or MHOM/GF/84/CAY-H-142) or L. venezuelensis ...

    • Leishmanicidal and trypanocidal activities of Bolivian medicinal plants 

      Fournet, Alain; Angelo Barrios, Alcira; Muñoz, Victoria (Journal of Ethnopharmacology, 1994)
      Abstract. Cutaneous and mucocutaneous leishmaniasis are endemic diseases in South America, especially in the subandean areas of the humid lowlands of Bolivia. Fourteen plants used topically in folk medicine to treat ...