• Ancient human genomes suggest three ancestral populations for present-day Europeans 

      Lazaridis, Iosif; Patterson, Nick; Mittnik, Alissa; Renaud, Gabriel; Mallick, Swapan; Kirsanow, Karola; Sudmant, Peter H; Schraiber, Joshua G; Castellano, Sergi; Lipson, Mark; Berger, Bonnie; Economou, Christos; Bollongino, Ruth; Fu, Q; Bos, Kirsten I; Nordenfelt, Susanne; Li, Heng; Filippo, Cesare de; Prüfer, Kay; Sawyer, Susanna; Posth, Cosimo; Haak, Wolfgang; Hallgren, Fredrik; Fornander, Elin; Rohland, Nadin; Delsate, Dominique; Francken, Michael; Guinet,Jean-Michel; Wahl, Joachim; Ayodo,George; Babiker, Hamza A; Bailliet. Graciela; Balanovska, Elena; Balanovsky,Oleg; Barrantes, Ramiro; Bedoya, Gabriel; Ben-Ami, Haim; Bene, Judit; Berrada, Fouad; Bravi, Claudio M; Brisighelli, Francesca; Busby, George BJ; Cali, Francesco; Churnosov, Mikhail; Cole, David EC; Corach, Daniel; Damba, Larissa; Driem, George van; Dryomov, Stanislav; Dugoujon, Jean-Michel; Fedorova, Sardana A; Gallego Romero, Irene; Gubina, Marina; Hammer, Michael; Henn, Brenna M; Hervig,Tor; Hodoglugil, Ugur; Jha, Aashish R; Karachanak-Yankova, Sena; Khusainova, Rita; Khusnutdinova, Elza; Kittles, Rick; Kivisild, Toomas; Klitz, William; Kucinskas, Vaidutis; Kushniarevich, Alena; Laredj, Leila; Litvinov, Sergey; Loukidis, Theologos; Mahley, Robert W; Melegh, Béla; Metspalu, Ene; Molina, Julio; Mountain, Joanna; Näkkäläjärvi, Klemetti; Nesheva, Desislava; Nyambo, Thomas; Osipova, Ludmila; Parik, Jüri; Platonov, Fedor; Posukh, Olga; Romano, Valentino; Rothhammer, Francisco; Rudan, Igor; Ruizbakiev, Ruslan; Sahakyan, Hovhannes; Sajantila, Antti; Salas, Antonio; Starikovskaya, Elena B; Tarekegn, Ayele; Toncheva, Draga; Turdikulova, Shahlo; Uktveryte, Ingrida; Utevska,Olga; Vasquez, René; Villena, Mercedes; Voevoda, Mikhail; Winkler, Cheryl A; Yepiskoposyan, Levon; Zalloua, Pierre; Zemunik, Tatijana; Cooper, Alan; Capelli, Cristian; Thomas, Mark G; Ruiz-Linares, Andres; Tishkoff, Sarah A; Singh, Lalji; Thangaraj, Kumarasamy; Villems, Richard; Comas, David; Sukernik, Rem; Metspalu, Mait; Meyer, Matthias; Eichler, Evan E; Burger, Joachim; Slatkin, Montgomery; Pääbo, Svante; Kelso, Janet; Reich, David; Krause, Johannes (Nature, 2014-09-18)
      We sequenced the genomes of a 7,000-year-old farmer from Germanyandeight 8,000-year-oldhunter-gatherersfromLuxembourg and Sweden. We analysed these and other ancient genomes1–4 with 2,345contemporaryhumanstoshowthatmostp ...
    • Apolipoprotein E/C1/C4/C2 gene cluster diversity in two native andean populations : Aymaras and Quechuas 

      Gayá-Vidal, Magdalena; Athanasiadis, Georgios; Carreras-Torres, Robert; Via, Marc; Esteban, Esther; Villena, Mercedes; Vásquez, René; Dugoujon, Jean-Michel; Moral, Pedro (Annals of Human Genetics, 2012-07)
      Summary. The APOE/C1/C4/C2 gene cluster presents high relevance in lipid metabolism and, therefore, has important epidemiological implications. Here, we study for the first time the variation patterns of 25 polymorphisms ...
    • Autosomal and X chromosome alu insertions in Bolivian aymaras and quechuas : two languages and one genetic pool 

      Gayà-Vidal, Magdalena; Dugoujon, Jean-Michel; Esteban, Esther; Athanasiadis, Georgios; Rodríguez, Armando; Villena, Mercedes; Vásquez, René; Moral, Pedro (American Journal of Human Biology, 2010)
      Abstract. Thirty-two polymorphic Alu insertions (18 autosomal and 14 from the X chromosome) were studied in 192 individuals from two Amerindian populations of the Bolivian Altiplano (Aymara and Quechua speakers: the two ...
    • Genetic variations in the TP53 pathway in native americans strongly suggest adaptation to the high altitudes of the andes 

      Jacovas, Vanessa Cristina; Rovaris, Diego Luiz; Pérez, Orlando; Azevedo, Soledad de; Macedo, Gabriel Souza; Sandoval, José Raul; Salazar-Granara, Alberto; Villena, Mercedes; Dugoujon, Jean-Michel; Bisso-Machado, Rafael; Petzi-Erler, María Luiza; Salzano, Francisco Mauro; Ashton-Prolla, Patricia; Ramallo, Virginia; Bortolini, María Cátira (PLOS One, 2015-09-18)
      Abstract. The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and LIF, rs929271) were studied in a total of ...
    • Latin Americans show wide-spread converso ancestry and imprint of local native ancestry on physical appearance 

      Chacón-Duque, Juan-Camilo; Adhikari, Kaustubh; Fuentes-Guajardo, Macarena; Mendoza-Revilla, Javier; Acuña-Alonzo, Víctor; Barquera, Rodrigo; Quinto-Sánchez, Mirsha; Gómez-Valdés, Jorge; Everardo Martínez, Paola; Villamil-Ramírez, Hugo; Hünemeier, Tábita; Ramallo, Virginia; Silva de Cerqueira, Caio C; Hurtado, Malena; Villegas, Valeria; Granja, Vanessa; Villena, Mercedes; Vásquez, René; Llop, Elena; Sandoval, José R; Salazar-Granara, Alberto; Parolin, María-Laura; Sandoval, Karla; Peñaloza-Espinoza, Rosenda I; Rangel-Villalobos, Héctor; Winkler, Cheryl A; Klitz, William; Bravi, Claudio; Molina, Julio; Corach, Daniel; Barrantes, Ramiro; Gomes, Verónica; Resende, Carlos; Gusmäo, Leonor; Amorin, Antonio; Xue, Yali; Dugoujon, Jean-Michel; Moral, Pedro; González-José, Rolando; Schuler-Faccini, Lavinia; Salzano, Francisco M; Bortolini, María-Cátira; Canizales-Quinteros, Samuel; Poletti, Giovanni; Gallo, Carla; Bedoya, Gabriel; Rothhammer, Francisco; Balding, David; Hellenthal, Garrett; Ruiz-Linares, Andrés (Nature communications, 2018)
      Abstract. Historical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. Using novel haplotype-based ...
    • mtDNA and y-chromosome diversity in aymaras and quechuas from Bolivia : different stories and special genetic traits of the andean altiplano populations 

      Gayà-Vidal, Magdalena; Moral, Pedro; Saenz-Ruales, Nancy; Gerbault, Pascale; Tonasso, Laure; Villena, Mercedes; Vasquez, René; Bravi, Claudio M; Dugoujon, Jean-Michel (American Journal of Physical Anthroplogy, 2011-04-05)
      Abstract. Two Bolivian samples belonging to the two main Andean linguistic groups (Aymaras and Quechuas) were studied for mtDNA and Y-chromosome uniparental markers to evaluate sex-specific differences and give new ...
    • Reconstructing native American population history 

      Reich, David; Patterson, Nick; Campbell, Desmond; Tandon, Arti; Mazieres, Stéphane; Ray, Nicolas; Parra, María V; Rojas, Winston; Duque, Constanza; Mesa, Natalia; García, Luis F; Triana, Omar; Blair, Silvia; Maestre, Armanda; Dib, Juan C; Bravi, Claudio M; Bailliet, Graciela; Corach, Daniel; Hünemeier, Tábita; Bortolini, María Cátira; Salzano, Francisco M; Petzl-Erler, María Luiza; Acuña-Alonzo, Víctor; Aguilar-Salinas, Carlos; Canizales-Quinteros, Samuel; Tusié-Luna, Teresa; Riba, Laura; Rodríguez-Cruz, Maricela; López-Alarcón, Mardia; Coral-Vázquez, Ramón; Canto-Cetina, Thelma; Silva Zolezzi, Irma; Fernández-López, Juan Carlos; Contreras, Alejandra V; Jiménez-Sánchez, Gerardo; Gómez-Vázquez, María José; Molina, Julio; Carracedo, Ángel; Salas, Antonio; Gallo, Carla; Poletti, Giovanni; Witonsky, David B; Alkorta-Aranburu, Gorka; Sukernik, Rem I; Osipova, Ludmila; Fedorova, Sardana A; Vasquez, René; Villena, Mercedes; Moreau, Claudia; Barrantes, Ramiro; Pauls, David; Excoffier, Laurent; Bedoya, Gabriel; Rothhammer, Francisco; Dugoujon, Jean-Michel; Larrouy, Georges; Klitz, William; Labuda, Damián; Kidd, Judith; Kidd, Kenneth; Di Rienzo, Anna; Freimer, Nelson B; Price, Alkes L; Ruiz-Linares, Andrés (NATURE, 2012-08-16)
      The peopling of the Americas has been the subject of extensive genetic, archaeological and linguistic research; however, central questions remain unresolved1–5. One contentious issue is whether the settlement occurred ...