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Programmation prénatale de l'acclimatation hématologique et respiratoire chez des rats de haute altitude
(Actas Club Recherché Clinique de Quebec, 2011)
Nous avons testé l’hypothèse selon laquelle l’hypoxie prénatale chez le rat aurait des
conséquences à long terme sur l’acclimatation physiologique à la haute altitude. Des rats
vivant en haute altitude (3600m, La Paz, ...
Divergent physiological responses in laboratory rats and mice raised at high altitude
(The Journal of Experimental Biology, 2015-01-29)
Abstract.
Ecological studies show that mice can be found at high altitude (HA – up to 4000 m) while rats are absent at these altitudes, and there are
no data to explain this discrepancy. We used adult laboratory rats ...
Comparative responses of arterial oxygen saturation and heart rate durign postnatal development in rats living at high and low altitude
(Actas Club Recherché Clinique de Quebec, 2011)
We used pulse oximetry to measure arterial oxygen saturation (SpO2) and heart rate (HR)
in 4 and 14 day-old rats raised at HA (La Paz, Bolivia, 3,600 m / 12,000ft) or at sea level
(SL, Québec, Canada). SpO2 and HR were ...
Enhanced erythropoietin expression in the brainstem of newborn rats at high altitude
(Neuroscience Letters, 2011)
Abstract.
In addition to its role in elevating red blood cell number, erythropoietin (Epo) exerts protective functions
against acute and delayed degenerative diseases of the brain. Moreover, we have recently demonstrated
that ...
Effects of prenatal hypoxia on hematological and respiratory acclimatization to high altitude in rats
(Actas Club Recherché Clinique de Quebec, 2011)
We tested the hypothesis that prenatal hypoxia have long-term consequences on
physiological acclimatization to high altitude in rats. Male and female high-altitude rats
(3600m, La Paz, Bolivia) were exposed to normal ...