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Exaggerated pulmonary hypertension and right ventricular dysfunction in high-altitude dwellers with patent foramen ovale
(Chest, 2015)
There is considerable interindividual variability in pulmonary artery pressure among high-altitude (HA) dwellers, but the underlying mechanism is not known. At low altitude, a patent foramen
ovale (PFO) is present in about ...
Exaggerated systemic oxidative-inflammatory-nitrosative stress in chronic mountain sIckness is associated with cognitive decline and depression
(J Physiol, 2019)
Abstract.
Chronic mountain sickness (CMS) is a maladaptation syndrome encountered at high altitude (HA) characterised by severe hypoxaemia that carries a higher risk of stroke and migraine and is associated with increased ...
EPR spectroscopic evidence of iron-catalysed free radical formation in chronic mountain sickness : dietary causes and vascualr consequences
(Free Radical Biology and Medicine, 2022)
Abstract
Chronic mountain sickness (CMS) is a high-altitude (HA) maladaptation syndrome characterised by elevated systemic oxidative-nitrosative stress (OXNOS) due to a free radical-mediated reduction in vascular nitric ...
Increasing respiratory dead space improves sleep disordered breathing and hypoxemia in patients with chronic mountain sickness
(The FASEB Journal, 2011-04-25)
Sleep-disordered breathing and vascular function in patients with chronic mountain sickness and healthy high-altitude dwellers
(CHEST, 2016-11-05)
BACKGROUND: Chronic mountain sickness (CMS) is often associated with vascular
dysfunction, but the underlying mechanism is unknown. Sleep-disordered breathing (SDB)
frequently occurs at high altitude. At low altitude, ...
Exercise induces rapid interstitial lung water accumulation in patients with chronic mountain sickness
(CHEST, 2012-04-04)
Background: Chronic mountain sickness (CMS) is a major public health problem in mountainous
regions of the world. In its more advanced stages, exercise intolerance is often found, but the
underlying mechanism is not ...
Exaggerated pulmonary hypertension during mild exercise in chronic mountain sickness
(CHEST, 2010-02)
Background: Chronic mountain sickness (CMS) is an important public health problem and is characterized by exaggerated hypoxemia, erythrocytosis, and pulmonary hypertension. While pulmonary hypertension is a leading cause ...
Exaggerated exercise-induced pulmonary hypertension causes lung water accumulation and right ventricular dysfunction in patients with chronic mountain sickness
(High Altitude Medicine & Biology, 2010-08-08)
Systemic vascular dysfunction in patients with chronic mountain sickness
(CHEST, 2012-01-01)
Background: Chronic mountain sickness (CMS) is a major public health problem characterized by
exaggerated hypoxemia and erythrocytosis. In more advanced stages, patients with CMS often
present with functional and structural ...
Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia
(Circulation, 2010-07-19)
Background—Adverse events in utero may predispose to cardiovascular disease in adulthood. The underlying mechanisms are unknown. During preeclampsia, vasculotoxic factors are released into the maternal circulation by the ...