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Increased incidence of preeclampsia lowers birth weight and increases intrauterine mortality at high altitude
(High Altitude Medicine & Biology, 2001)
The relationship between perinatl hypoxia and sleep-disordered breathing in preclinical chronic mountain sickness
(High Altitude Medicine & Biology, 2010-08-08)
Introduction: Chronic intermittent hypoxia due to sleepdisordered breathing is implicated as a potential etiological
factor for chronic mountain sickness (CMS). Whether sleepdisordered breathing precedes or results from ...
A genomewide admixture mapping panel for hispanic/latino populations
(The American Journal of Human Genetics, 2007-06)
Admixture mapping (AM) is a promising method for the identification of genetic risk factors for complex traits and
diseases showing prevalence differences among populations. Efficient application of this method requires the ...
Does chronic mountain sickness (CMS) have perinatal origins?
(Respiratory Physiology & Neurobiology, 2007-06-29)
Abstract.
Chronic mountain sickness (CMS) occurs in 10% of male high-altitude residents. It is characterized by hypoventilation and hypoxemia but its underlying cause remains unknown. We hypothesized that CMS' origins ...
Intrauterine growth restriction, preeclampsia, and intrauterine mortality at high altitude in Bolivia
(PEDIATRIC RESEARCH, 2003-02-18)
Abstract.
Infant mortality and stillbirth rates in Bolivia are high and birth weights are low compared with other South American countries. Most Bolivians live at altitudes of 2500 m or higher. We sought to determine the ...
Consensus statement on chronic and subacute high altitude diseases
(High Altitude Medicine & Biology, 2005)
ABSTRACT.
This is an international consensus statement of an ad hoc committee formed by the In
ternational Society for Mountain Medicine (ISMM) at the VI World Congress on Mountain Med
icine and High Altitude Physiology ...
Maternal adaptation to high-altitude pregnancy : an experiment of nature-a review
(Placenta, 2004)
A long and productive history of studies at high altitude has demonstrated that chronic hypoxia plays a key role in the aetiology of intrauterine growth restriction (IUGR) and pre-eclampsia. Susceptibility to altitude-associated ...
High-altitude ancestry protects against IUGR and reductions in birth weight associated with high altitude and preeclampsia
(High Altitude Medicine & Biology, 2005-02-22)
Background.
Observations consistently demonstrate diminished birth weight [BW] with ascending altitude;
however population comparisons reveal the extent of BW
reduction depends, in part, upon high-altitude ancestry.
...
High-altitude ancestry protects against hypoxia-associated reductions in fetal growth
(Archives of Disease in Childhood-Fetal and Neonatal, 2007-02-28)
Objective: The chronic hypoxia of high-altitude (>2500 m) residence has been shown to decrease birth
weight in all populations studied to date. However, multigenerational high-altitude populations appear
protected relative ...
Evidence that parent-of-origin affects birth-weight reductions at high altitude
(American Journal of Human Biology, 2008-02-19)
Abstract.
Hypoxia exerts a profound depressant effect on fetal growth, lowering birth weight, and raising mortality risk. Multigenerational high-altitude populations are relatively protected from this birth-weight decline, ...