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Erythropoietin (EPO) in human milk : potential enteral factor in high altitude hypoxia
(High Altitude Medicine & Biology, 2010-08-08)
Introduction: Erythropoietin (Epo) is a normal constituent of
human milk. At sea level, it was found that mean milk-borne
Epo concentrations are within the normal range for plasma
Epo concentrations and rise with ...
Adrenocortical suppression in highland chick embryos is restored during incubation at sea level
(High Altitude Medicine & Biology, 2011)
Abstract.
By combining the chick embryo model with incubation at high altitude, this study tested the hypothesis that
development at high altitude is related to a fetal origin of adrenocortical but not adrenomedullary ...
Perinatal hypoxia increases susceptibility to high-altitude polycythemia and attendant pulmonary vascular dysfunction
(Am J Physiol Heart Circ Physiol, 2015-04-27)
Perinatal hypoxia increases susceptibility to high-altitude polycythemia and
attendant pulmonary vascular dysfunction. Am J Physiol Heart Circ
Physiol 309: H565–H573, 2015. First published June 19, 2015;
doi:10.1152/a ...
Concentración de Malondialdehido en sujetos que residen a gran altitud : estudio exploratorio
(Rev Peru Med Exp Salud Pública, 2017-12-07)
Resumen. El objetivo fue investigar el comportamiento del malondialdehido (MDA), biomarcador de estrés oxidativo, a grandes altitudes (3500–4200 m de altitud). Se realizó un estudio exploratorio en 91 sujetos de las ciudades ...
Cardiac and vascular disease prior to hatching in chick embryos incubated at high altitude
(Journal of Developmental Origins of Health and Disease, 2010)
Abstract.
The partial contributions of reductions in fetal nutrition and oxygenation to slow fetal growth and a developmental origin of cardiovascular disease remain unclear. By combining high altitude with the chick ...
Acute hypoxia-reoxygenation and vascular oxygen sensing in the chicken embryo
(Physiological Reports, 2017)
Abstract.
Fetal/perinatal hypoxia is one of the most common causes of perinatal morbidity and mortality and is frequently accompannied by vascular dysfunction. However, the mechanisms involved have not been fully delineated. ...
Graduated effects of high-altitude hypoxia and highland ancestry on birth size
(Pediatric Research, 2013-10-02)
Background: We present a cohort of ca. 25,000 birth
records from Bolivia of men and women who are currently
adults. We used this cohort to test the hypothesis that high
altitude reduces birth weight and that highland ...
Potential role for elevated maternal enzymatic antioxidant status in Andean protection against altitude-associated SGA
(The Journal of Maternal-Fetal and Neonatal Medicine, 2012)
Oxidative stress has been implicated in the uteroplacental
ischemia characteristic of preeclampsia and small-for-gestational-age (SGA) birth, both of which are more common at high
(>2500 m) vs low altitude. Since Andeans ...
Neonatal oxygenation, pulmonary hypertension, and evolutionary adaptation to high altitutde (2013 Grover Conference series)
(Pulm Circ, 2015-03)
Abstract.
Andeans and Tibetans have less altitude reduction in birth weight than do shorter-resident
groups, but only Tibetans are protected from pulmonary hypertension and chronic mountain sickness
(CMS). We hypothesized ...
Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia
(Circulation, 2010-07-19)
Background—Adverse events in utero may predispose to cardiovascular disease in adulthood. The underlying mechanisms are unknown. During preeclampsia, vasculotoxic factors are released into the maternal circulation by the ...