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Response to letters regarding article, "Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia"
(Circulation, 2011)
We thank Lazdam et al and Yuan et al for their interesting
comments on our study.1 Lazdam et al point out that in our study,
birth weight in offspring of mothers with preeclampsia was significantly lower than in controls, ...
Comparative responses of arterial oxygen saturation and heart rate durign postnatal development in rats living at high and low altitude
(Actas Club Recherché Clinique de Quebec, 2011)
We used pulse oximetry to measure arterial oxygen saturation (SpO2) and heart rate (HR)
in 4 and 14 day-old rats raised at HA (La Paz, Bolivia, 3,600 m / 12,000ft) or at sea level
(SL, Québec, Canada). SpO2 and HR were ...
Enhanced erythropoietin expression in the brainstem of newborn rats at high altitude
(Neuroscience Letters, 2011)
Abstract.
In addition to its role in elevating red blood cell number, erythropoietin (Epo) exerts protective functions
against acute and delayed degenerative diseases of the brain. Moreover, we have recently demonstrated
that ...
Higher estrogen levels during pregnancy in Andean than European residents of high altitude suggest differences in aromatase activity
(J Clin Endocrinol Metab, 2014-08)
Context: Uteroplacental hypoxia has been reported to lower estrogen levels in preeclampsia as the
result of reduced aromatase activity.
Objective: We asked whether the chronic hypoxia of residence at high altitude in the ...
Effects of prenatal hypoxia on hematological and respiratory acclimatization to high altitude in rats
(Actas Club Recherché Clinique de Quebec, 2011)
We tested the hypothesis that prenatal hypoxia have long-term consequences on
physiological acclimatization to high altitude in rats. Male and female high-altitude rats
(3600m, La Paz, Bolivia) were exposed to normal ...
Influencia de la hipoxia intermitente en el mal crónico de montaña y su implicancia en la terapéutica
(COLEGIO MEDICO DE BOLIVIA, 2016-02-24)
Plasma antioxidant capacity in highland subjects exposed at 5200 meters of altitude
(Revista Boliviana de Química, 2014-06-30)
Abstract.
Human exposure to high altitude conditions (reduced barometric pressure) leads to the formation of free radicals,
which could be a major cause of altitude sickness. In the present study the total antioxidant ...
Determinación de distancia recorrida y variación de parámetros respiratorios y cardiovasculares, antes y después de la prueba de caminata de 6 minutos, en nativos y residentes permanentes de altura clinicamente sanos
(Rev Med (La Paz), 2014-01)
Resumen.
Objetivo:Determinar la distancia recorrida y la variación de parámetros respiratorios
y cardiovasculares antes y después de la prueba de caminata de los 6 minutos
(PC6M) en nativos y residentes permanentes de ...
Maternal and fetoplacental hypoxia do not alter circulating angiogenec growth effectors during human pregnancy
(Biol Reprod., 2014-02-27)
Abstract.
One causal model of preeclampsia (PE) postulates that
placental hypoxia alters the production of angiogenic growth
effectors (AGEs), causing an imbalance leading to maternal
endothelial cell dysfunction. We ...
Fisiología del ejercicio en la altura
(COLEGIO MEDICO DE BOLIVIA, 2016-02)
RESUMEN.
La fisiología del ejercicio es la ciencia que estudia las modificaciones en la estructura y función de los órganos y sistemas que integran el cuerpo humano y su relación con el medio externo durante el ejercicio ...