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New data demonstrates that relationship of salivary to serum progesterone in Bolivian women is comparable to that in other populations
dc.contributor.author | Thornburg, Jonathan | |
dc.contributor.author | Bellido, Diva | |
dc.contributor.author | Stewart, Rose | |
dc.contributor.author | Spielvogel, Hilde | |
dc.contributor.author | Echalar, Lourdes | |
dc.contributor.author | Burch, Jennifer | |
dc.contributor.author | Vitzthum, Virginia J | |
dc.date.accessioned | 2016-09-29T15:27:10Z | |
dc.date.available | 2016-09-29T15:27:10Z | |
dc.date.issued | 2011-04-13 | |
dc.identifier.uri | http://repositorio.umsa.bo/xmlui/handle/123456789/8090 | |
dc.description.abstract | Abstract. Salivary progesterone (P) concentration is widely used in field studies as a relatively easy-to-measure proxy for serum P. Chatterton et al. [Fertility & Sterility 86:723 (2006)] compared sample means of salivary and serum P in concurrent samples taken during the putative luteal phase from women in La Paz, Bolivia (n526) and Chicago, USA (n520). They concluded that salivary/serum P ratios (hereinafter ‘‘uptake fractions’’) vary significantly among populations (precluding crosspopulational comparisons of salivary P), and that salivary P may not be a reliable proxy for serum P in Bolivian and other non-industrialized populations. We have previously disputed this claim [AJHB 21:271 (2008)], arguing that sample contamination and/or assay errors are more plausible explanations for Chatterton et al.’s data. Here we report analyses of new data collected specifically to investigate the relationship of salivary P 280 ABSTRACTS to serum P in Bolivian women. Simultaneous saliva/serum samples (n572) from 36 women were collected approximately one and three weeks following the preceding menses; samples were subsequently assigned to an ovarian-cycle phase based on the date of the subsequent menses. As did Chatterton et al., here we focus on the luteal-phase data. We find an excellent correlation (r50.78) between salivary and serum P in these samples, with uptake fractions typically around 3%, similar to published reports of this ratio in other populations. We conclude that salivary P is a reliable proxy for serum P in Bolivian women and (assuming comparable assays) that comparisons of salivary P are valid across populations. | es_ES |
dc.language.iso | en | es_ES |
dc.publisher | 36th Annual Meeting Minnesota | es_ES |
dc.subject | PROGESTERONA SALIVAL | es_ES |
dc.subject | MUJERES EN BOLIVIA | es_ES |
dc.subject | PROGESTERONA SÈRICA | es_ES |
dc.title | New data demonstrates that relationship of salivary to serum progesterone in Bolivian women is comparable to that in other populations | es_ES |
dc.type | Article | es_ES |