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  • Genetic variations in the TP53 pathway in native americans strongly suggest adaptation to the high altitudes of the andes 

    Jacovas, Vanessa Cristina; Rovaris, Diego Luiz; Pérez, Orlando; Azevedo, Soledad de; Macedo, Gabriel Souza; Sandoval, José Raul; Salazar-Granara, Alberto; Villena, Mercedes; Dugoujon, Jean-Michel; Bisso-Machado, Rafael; Petzi-Erler, María Luiza; Salzano, Francisco Mauro; Ashton-Prolla, Patricia; Ramallo, Virginia; Bortolini, María Cátira (PLOS One, 2015-09-18)
    The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and LIF, rs929271) were studied in a total of 282 individuals ...