Now showing items 1-20 of 41

    • Absence of work efficiency differences during cycle ergometry exercise in Bolivian Aymara 

      Brutsaert, Tom D; Haas, Jere D; Spielvogel, Hil (High Altitude Medicine & Biology, 2004)
      ABSTRACT This study tested the hypothesis that Andean natives are adapted to high altitude (HA) via high work ef ficiency during exercise in hypoxia. A total of 186 young males and females were tested in Bo livia, ...
    • Acute hypoxia-reoxygenation and vascular oxygen sensing in the chicken embryo 

      Mohammed, Riazuddin; Salinas, Carlos E; Giussani, Dino A; Blanco, Carlos E; Cogolludo, Angel L; Villamor, Eduardo (Physiological Reports, 2017)
      Abstract Fetal/perinatal hypoxia is one of the most common causes of perinatal morbidity and mortality and is frequently accompannied by vascular dysfunction. However, the mechanisms involved have not been fully delineated. ...
    • Adrenergic system in high altitude residents 

      Antezana, AM; Richalet, JP; Antezana, G; Spielvogel, H; Kacimi, R (Int. J Sports. Med, 1992)
      Heart rate (HR) response to isoproterenol (ISO) infusion (IP) is decreased in normal sea level (SL) natives exposed to high altitude (HA). Since norepinephrine plasma concentration is higher in HA hypoxia, a downregulation ...
    • Adrenocortical suppression in highland chick embryos is restored during incubation at sea level 

      Salinas Salmón, Carlos E; Villena, Mercedes; Blanco, Carlos E; Giussani, Dino A (High Altitude Medicine & Biology, 2011)
      Abstract Salinas, Carlo E., Mercedes Villena, Carlos E. Blanco, and Dino A. Giusssani. Adrenocortical suppression in highland chick embryos is restored during incubation at sea level. High Alt. Med. Biol. 12:79–87, ...
    • Augmented uterine artery blood flow and oxygen delivery protect andeans from altitude-associated reductions in fetal growth 

      Julian, Colleen Glyde; Wilson, Megan J; Lopez, Miriam; Yamashiro, Henry; Tellez, Wilma; Rodriguez, Armando; Bigham, Abigail W; Shriver, Mark D; Rodriguez, Carmelo; Vargas, Enrique; Moore, Lorna G (Am J Physiol Regul Integr Comp Physiol, 2009-02-20)
      A b s t r a c t The effect of high altitude on reducing birth weight is markedly less in populations of high- (e.g., Andeans) relative to low-altitude origin (e.g., Europeans). Uterine artery (UA) blood flow is greater ...
    • Capacidad aeróbica de deportistas de diferentes disciplinas 

      Soria, R; Spielvogel, H (COLEGIO MEDICO DE BOLIVIA, 2016-02)
      RESUMEN OBJETIVOS.- Comprobar si el efecto de la hipoxia de altura repercute de la misma manera en las disciplinas deportivas al margen de su predominancia respecto a la dependencia del oxígeno. MATERIAL Y METODOS.- El ...
    • Chemoreflex ventilatory response to CO₂ in man at low and high altitudes 

      Lefrançois, R; Gautier, H; Pasquis, P; Cevaer, AM; Hellot, MF; Leroy, J (Respiration Physiology, 1972)
      Abstract. On man, a peripheral chemoreflex ventilatory response curve was obtained by measuring ventilatory reactions to the transient inhalation of a CO₂-rich mixture. Experiments have been performed. 1) on lowlanders ...
    • Concentración de Malondialdehido en sujetos que residen a gran altitud: estudio exploratorio 

      Melgarejo Pomar, Ingrid Gaby; Balanza Erquicia, Elfride; Torrez Colmena, Lizeth; Quisberth Barrera, Sergio; Suzaño Vargas, Pilar Leina (Rev Peru Med Exp Salud Pública, 2017-12-07)
      El objetivo fue investigar el comportamiento del malondialdehido (MDA), biomarcador de estrés oxidativo, a grandes altitudes (3500–4200 m de altitud). Se realizó un estudio exploratorio en 91 sujetos de las ciudades de La ...
    • Consensus statement on chronic and subacute high altitude diseases 

      León-Velarde, Fabiola; Maggiorini, Marco; Reeves, John T; Aldashev, Almaz; Asmus, Ingrid; Bernardi, Luciano; Ge, Ri-Li; Hackett, Peter; Kobayashi, Toshio; Moore, Lorna G; Peñaloza, Dante; Richalet, Jean-Paul; Roach, Robert; Wu, Tianyi; Vargas, Enrique; Zubieta-Castillo, Gustavo; Zubieta-Calleja, Gustavo (High Altitude Medicine & Biology, 2005)
      ABSTRACT This is an international consensus statement of an ad hoc committee formed by the In ternational Society for Mountain Medicine (ISMM) at the VI World Congress on Mountain Med icine and High Altitude Physiology ...
    • Desadaptación crónica a la vida en la altura 

      Villena Cabrera, Mercedes (Anales de la Academia Boliviana de Medicina, 2004)
      Cuando humanos o animales son transportados del nivel del mar a alturas elevadas, son expuestos a una presión disminuida de oxígeno. Como consecuencia se ponen en marcha procesos que se pueden denominar de aclimatación y ...
    • Determinants of blood oxygenation during pregnancy in Andean and Europeas residents of high altitude 

      Vargas, Marco; Vargas, Enrique; Julian, Colleen Glyde; Armaza, J Fernando; Rodriguez, Armando; Tellez, Wilma; Niermeyer, Susan; Wilson, Megan; Parra, Esteban; Shriver, Mark; Moore, Lorna G (Am J Physiol Regul Integr Comp Physiol, 2007-07-02)
      High altitude decreases birth weight, but this effect is diminished in long vs. short-resident, high-altitude populations. We asked whether women from long vs. short-resident, high-altitude populations had higher arterial ...
    • Débit et distensibilité vasculaires cutanés post-ischémiques chez l'homme 

      Seroussi, S; Durand, J; Verpillat, JM; Pradel, M; Martineaud, JP (Pflügers Arch., 1973)
      On sait que les vaisseaux cutanés sont sensibles à I'hypoxie aiguë et chronique, par inhalation de mélanges hypoxiques ou séjour à l'altitude (Thron, 1961 ; Durand, 1967). Vaisseaux résistifs et capacitifs sont sous Ia ...
    • Do cytokines contribute to the andean-associated protection from reduced fetal growth at high altitude? 

      Dávila, R Daniela; Julian, Colleen Glyde; Wilson, Megan J; Browne, Vaughn A; Rodriguez, Carmelo; Bigham, Abigail W; Shriver, Mark D; Vargas, Enrique; Moore, Lorna G (Reproductive Sciences, 2011)
      Abstract Pro- versus anti-inflammatory cytokine balance is important for successful pregnancy. Chronic hypoxia alters cytokine levels and increases the frequency of fetal growth restriction (FGR). Multigenerational Andean ...
    • Does chronic mountain sickness (CMS) have perinatal origins? 

      Moore, Lorna G; Niermeyer, Susan; Vargas, Enrique (Respiratory Physiology & Neurobiology, 2007-06-29)
      A b s t r a c t Chronic mountain sickness (CMS) occurs in 10% of male high-altitude residents. It is characterized by hypoventilation and hypoxemia but its underlying cause remains unknown. We hypothesized that CMS' ...
    • Dopaminergic metabolism in carotid bodies and high altitude acclimatization in female rats 

      Joseph, Vincent; Soliz, Jorge; Soria, Rudy; Pequignot, Jacqueline; Favier, Roland; Spielvogel, Hilde; Pequignot, Jean Marc (Am J Physiol Relulatory, 2002-04)
      We tested the hypothesis that ovarian steroids stimulate breathing through a dopaminergic mechanism in the carotid bodies (CB). In ovariectomized female rats raised at sea level, domperidone, a peripheral D2 receptor ...
    • Efectos circulatorios durante hiperoxia e hipoxia breves en residentes de las grandes alturas y en individuos transplantados a la misma La Paz - 3.600 m. 

      Coudert, J; Paz-Zamora, M; Antezana, G (Instituto Boliviano de Biología de Altura, 1972)
      Ya está completamente establecido que los individuos que nacen y viven a grandes alturas, presentan en relación con los individuos de nivel del mar, una disminución de sensibilidad ventilatoria al oxígeno (SEVERINGHAUS y ...
    • Effects of hypoxia and hyperoxia of short duration on the pulmonary circulation of highlanders (HL) and lowlanders (LL) living at 3,750 m 

      Coudert, J; Paz-Zamora, M; Antezana, G; Vargas, E; Briançon, L (Progress in Respiration Research, 1975)
      Summary We have done brief O₂ and N₂ inhalations in order to analyze the mechanism responsible for the pulmonary artery hypertension observed at high altitude in normal residents and newcomers. The reactivity of the ...
    • Effets sur la pression artérielle pulmonaire moyenne et la fréquence cardiaque d'une hyper ou hypoxie brève chez l'homme résident ou transplanté à 3.750 m. 

      Coudert, J; Paz-Zamora, M; Antezana, G; Gascard, JP (Journal de Physiologie, 1971)
      En étudiant les effets ventilatoires secondaires à l’inhalation brève de O₂ pur (Test O₂ -- Dejours – 1962) il a été montré que les natifs de l’altitude sont moins sensibles au stimulus oxygène que les gens venus du niveau ...
    • Erythropoietin (EPO) in human milk : potential enteral factor in high altitude hypoxia 

      Gonzales, Marcelino; Bellido, Diva; Soliz, Jorge (High Altitude Medicine & Biology, 2010-08-08)
      Introduction: Erythropoietin (Epo) is a normal constituent of human milk. At sea level, it was found that mean milk-borne Epo concentrations are within the normal range for plasma Epo concentrations and rise with ...
    • Estudios respiratorios en mujeres a grandes alturas (3.600 m. y 5.200 m.) 

      Cudkowicz, L; Spielvogel, H (Instituto Boliviano de Biología de Altura, 1979)
      Resumen. En dos alturas (3.600 m. y 5.200 m.) mujeres nativas residentes (A) mostraron una PACO2 y una PaCO2 más elevadas, una PAO2, PaO2 y pH arterial más bajos que hombres nativos (C) de una edad similar. La ventilación ...