• High-end arteriolar resistance limits uterine artery blood flow and restricts fetal growth in preeclampsia and gestational hypertension at high altitude 

      Browne, Vaughn A; Toledo-Jaldín, Lilian; Dávila, R Daniela; López, Luis P; Yamashiro, Henry; Cioffi-Ragan, Darleen; Julian, Colleen Glyde; Wilson, Megan J; Bigham, Abigail W; Shriver, Mark D; Honigman, Benjamín; Vargas, Enrique; Roach, Robert; Moore, Lorna G (Am J Physiol Regul Integr Comp Physiol, 2011)
      The reduction in infant birth weight and increased frequency of preeclampsia (PE) in high-altitude residents have been attributed to greater placental hypoxia, smaller uterine artery (UA) diameter, and lower UA blood ...
    • Preeclampsia and risk of maternal pulmonary hypertension at high altitude in Bolivia 

      Salinas, CE; Patey, OV; Murillo, C; Gonzales, M; Espinoza, V; Mendoza, S; Ruiz, R; Vargas, R; Perez, Y; Montaño, J; Toledo-Jaldin, L; Badner, A; Jimenez, J; Peñaranda, J; Romero, C; Aguilar, M; Riveros, L; Arana, I; Giussani, DA (Journal of Developmental Origins of Health and Disease, 2023)
      Abstract. Women with a history of preeclampsia (PE) have a greater risk of pulmonary arterial hypertension (PAH). In turn, pregnancy at high altitude is a risk factor for PE. However, whether women who develop PE during ...
    • Unique DNA methylation patterns in offspring of hypertensive pregnancy 

      Julian, Colleen Glyde; Pedersen, Brent S; Salinas Salmón, Carlos; Yang, Ivana V; Gonzales, Marcelino; Vargas, Enrique; Moore, Lorna G; Schwartz, David A (Clin Transl Sci., 2015)
      Abstract. Epigenomic processes are believed to play a pivotal role for the effect of environmental exposures in early life to modify disease risk throughout the lifespan. Offspring of women with hypertensive complications ...