• Unique DNA methylation patterns in offspring of hypertensive pregnancy 

      Julian, Colleen Glyde; Pedersen, Brent S; Salinas Salmón, Carlos; Yang, Ivana V; Gonzales, Marcelino; Vargas, Enrique; Moore, Lorna G; Schwartz, David A (Clin Transl Sci., 2015)
      Abstract. Epigenomic processes are believed to play a pivotal role for the effect of environmental exposures in early life to modify disease risk throughout the lifespan. Offspring of women with hypertensive complications ...
    • Uterine artery blood flow during pregnancy in high-altitude aymara women 

      Wilson, Megan; Niermeyer, Susan; Armaza, J Fernando; López, Miriam; Vargas, Enrique; Moore, Lorna G (High Altitude Medicine & Biology, 2003-02-19)
      Background. Birth weight falls with increasing altitude as the result of intrauterine growth restriction (IUGR) likely due, in turn, to lower uterine artery (UtA) blood flow. The altitude-associated birth weight decline is ...
    • Uterine artery blood flow, fetal hypoxia and fetal growth 

      Browne, Vaughn A.; Julian, Colleen G.; Toledo-Jaldín, Lilian; Cioffi-Ragan, Darleen; Vargas, Enrique; Moore, Lorna G (Philosophycal Transactions B, 2015-03-13)
      Evolutionary trade-offs required for bipedalism and brain expansion influence the pregnancy rise in uterine artery (UtA) blood flow and, in turn, reproductive success. We consider the importance of UtA blood flow by ...
    • Ventilation and hypoxic ventilatory response of Tibetan and Aymara high altitude natives 

      Beall, Cynthia M; Strohl, Kingman P; Blangero, John; Williams-Blangero, Sarah; Almasy, Laura A; Decker, Michael J; Worthman, Carol M; Goldstein, Melvyn C; Vargas, Enrique (American Journal Physical Anthropology, 1997)
      ABSTRACT. Newcomers acclimatizing to high altitude and adult male Tibetan high altitude natives have increased ventilation relative to sea level natives at sea level. However, Andean and Rocky Mountain high altitude natives ...
    • Where the O2 goes to : preservation of human fetal oxygen delivery and consumption at high altitude 

      Postigo, Lucrecia; Heredia, Gladys; Illsley, Nicholas P; Torricos, Tatiana; Dolan, Caitlin; Echalar, Lourdes; Téllez, Wilma; Maldonado, Iván; Brimacombe, Michael; Balanza, Elfride; Vargas, Enrique; Zamudio, Stacy (The Journal of Physiology, 2009)
      Fetal growth is decreased at high altitude (> 2700 m). We hypothesized that variation in fetal O2 delivery might account for both the altitude effect and the relative preservation of fetal growth in multigenerational ...