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High-altitude hypoxia and echocardiographic indices of pulmonary hypertension in male and female chickens at adulthood
(Circulation Journal, 2014-06)
Background: By combining the chick embryo model with incubation at high altitude (HA), the effects of chronic hypoxia on fetal growth, fetal cardiac and aortic wall remodeling and systemic arterial blood pressure at adulthood ...
Adrenocortical suppression in highland chick embryos is restored during incubation at sea level
(High Altitude Medicine & Biology, 2011)
Abstract.
By combining the chick embryo model with incubation at high altitude, this study tested the hypothesis that
development at high altitude is related to a fetal origin of adrenocortical but not adrenomedullary ...
Exaggerated pulmonary hypertension and right ventricular dysfunction in high-altitude dwellers with patent foramen ovale
(Chest, 2015)
There is considerable interindividual variability in pulmonary artery pressure among high-altitude (HA) dwellers, but the underlying mechanism is not known. At low altitude, a patent foramen
ovale (PFO) is present in about ...
Apolipoprotein E/C1/C4/C2 gene cluster diversity in two native andean populations : Aymaras and Quechuas
(Annals of Human Genetics, 2012-07)
Summary.
The APOE/C1/C4/C2 gene cluster presents high relevance in lipid metabolism and, therefore, has important epidemiological implications. Here, we study for the first time the variation patterns of 25 polymorphisms ...
Increasing respiratory dead space improves sleep disordered breathing and hypoxemia in patients with chronic mountain sickness
(The FASEB Journal, 2011-04-25)
Sleep-disordered breathing and vascular function in patients with chronic mountain sickness and healthy high-altitude dwellers
(CHEST, 2016-11-05)
BACKGROUND: Chronic mountain sickness (CMS) is often associated with vascular
dysfunction, but the underlying mechanism is unknown. Sleep-disordered breathing (SDB)
frequently occurs at high altitude. At low altitude, ...
Reconstructing native American population history
(NATURE, 2012-08-16)
The peopling of the Americas has been the subject of extensive
genetic, archaeological and linguistic research; however, central
questions remain unresolved1–5. One contentious issue is whether
the settlement occurred ...
Exercise induces rapid interstitial lung water accumulation in patients with chronic mountain sickness
(CHEST, 2012-04-04)
Background: Chronic mountain sickness (CMS) is a major public health problem in mountainous
regions of the world. In its more advanced stages, exercise intolerance is often found, but the
underlying mechanism is not ...
Exaggerated pulmonary hypertension during mild exercise in chronic mountain sickness
(CHEST, 2010-02)
Background: Chronic mountain sickness (CMS) is an important public health problem and is characterized by exaggerated hypoxemia, erythrocytosis, and pulmonary hypertension. While pulmonary hypertension is a leading cause ...
Exaggerated exercise-induced pulmonary hypertension causes lung water accumulation and right ventricular dysfunction in patients with chronic mountain sickness
(High Altitude Medicine & Biology, 2010-08-08)