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Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas
(PLOS Genetics, 2012-03-08)
Abstract.
Most individuals throughout the Americas are admixed descendants of Native American, European, and African ancestors.
Complex historical factors have resulted in varying proportions of ancestral contributions ...
Apolipoprotein E/C1/C4/C2 gene cluster diversity in two native andean populations : Aymaras and Quechuas
(Annals of Human Genetics, 2012-07)
Summary.
The APOE/C1/C4/C2 gene cluster presents high relevance in lipid metabolism and, therefore, has important epidemiological implications. Here, we study for the first time the variation patterns of 25 polymorphisms ...
Calidad del informe pericial en los consultorios médico forenses de la ciudad de El Alto – enero 2010
(2012)
Se realizó un estudio Descriptivo de corte transversal con el objetivo de conocer la calidad del informe pericial que extiende el servicio de Medicina Forense que brinda el Instituto de Investigaciones Forenses en la ...
Life-long consequences of postnatal normoxia exposure in rats raised at high altitude
(J Appl Physiol., 2012)
Abstract.
We tested the hypothesis that exposure of high-altitude (HA) rats to a period of postnatal normoxia has long-term consequences on the ventilatory and hematological acclimatization in adults. Male and female HA ...
Systemic vascular dysfunction in patients with chronic mountain sickness
(CHEST, 2012-01-01)
Background: Chronic mountain sickness (CMS) is a major public health problem characterized by
exaggerated hypoxemia and erythrocytosis. In more advanced stages, patients with CMS often
present with functional and structural ...
Reconstructing native American population history
(NATURE, 2012-08-16)
The peopling of the Americas has been the subject of extensive
genetic, archaeological and linguistic research; however, central
questions remain unresolved1–5. One contentious issue is whether
the settlement occurred ...
Exercise induces rapid interstitial lung water accumulation in patients with chronic mountain sickness
(CHEST, 2012-04-04)
Background: Chronic mountain sickness (CMS) is a major public health problem in mountainous
regions of the world. In its more advanced stages, exercise intolerance is often found, but the
underlying mechanism is not ...
Potential role for elevated maternal enzymatic antioxidant status in Andean protection against altitude-associated SGA
(The Journal of Maternal-Fetal and Neonatal Medicine, 2012)
Oxidative stress has been implicated in the uteroplacental
ischemia characteristic of preeclampsia and small-for-gestational-age (SGA) birth, both of which are more common at high
(>2500 m) vs low altitude. Since Andeans ...
Role of cytokines in altitude-associated preeclampsia
(Pregnancy Hypertens, 2012-01)
Abstract.
Background: Preeclampsia (PE) is more common at high than low altitude and contributes
to the altitude-related decline in birth weight. Since inflammatory markers are implicated
in PE, we asked if such markers ...
Variables de hiperfusion tisular y su relación con la mortalidad en pacientes con shock séptico, Unidad de Terapia Intensiva Instituto Nacional de Tórax Gestión 2011
(2012)
El shock séptico, se ha constituido en los últimos años en una importante causa de morbi-mortalidad en las Unidades de Cuidados Intensivos, constituyéndose en la enfermedad más prevalente en el campo de la Medicina Intensiva ...