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Reduced endothelin-1 (ET-1) and elevated nitric oxide metabolites (NOX) across pregnancy among andean vs. european women at high (3100-3600 m) altitude
(High Altitude Medicine & Biology, 2005-02-22)
Background.
A consistent reduction in infant birth
weight occurs with ascending altitude; however multigenerational high-altitude residents [Andeans] demonstrate a degree of protection from altitude-associated
IUGR ...
Augmented uterine artery blood flow and oxygen delivery protect andeans from altitude-associated reductions in fetal growth
(Am J Physiol Regul Integr Comp Physiol, 2009-02-20)
Abstract.
The effect of high altitude on reducing birth weight is markedly less in
populations of high- (e.g., Andeans) relative to low-altitude origin
(e.g., Europeans). Uterine artery (UA) blood flow is greater ...
Greater uterine artery blood flow during pregnancy in multigenerational (Andean) than shorter-term (European) high-altitude residents
(Am J Physiol Regul Integr Comp Physiol, 2007)
Multigenerational (Andean) compared with shorter-term (European) high-altitude
residents exhibit less hypoxia-associated reductions in birth
weight. Because differences in arterial O2 content are not responsible,
we ...