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Aymara children are protected from high-altitude-induced pulmonary hypertension
(High Altitude Medicine & Biology, 2005-02-22)
Pulmonary hypertension is a hallmark of the adaptation to ambient lack of oxygen. This assumption is also
thought to hold true for high-altitude native children,
since invasive studies showed elevated pulmonary-artery
pressure ...
Oxidative-nitrosative stress and systemic vascular function in highlanders with and without exaggerated hypoxemia
(CHEST, 2013-02-01)
Background: Acute exposure to high altitude stimulates free radical formation in lowlanders, yet
whether this persists during chronic exposure in healthy, well-adapted and maladapted highlanders suffering from chronic ...
Offspring of preeclamptic mothers are predisposed to hypoxic pulmonary hypertension
(High Altitude Medicine & Biology, 2005-02-22)
Adverse events in utero may predispose to cardiovascular disease in adulthood. In preeclampsia, the diseased placenta releases circulating vasculotoxic factors
that cause maternal endothelial dysfunction. These factors ...
Pulmonary-artery pressure and exhaled nitric oxide in Bolivian and caucasian high altitude dwellers
(High Altitude Medicine & Biology, 2008)
Abstract.
There is evidence
that high altitude populations may be better protected from hypoxic pulmonary hypertension than low altitude natives, but the underlying mechanism is incompletely understood. In Tibetans, ...
Response to letters regarding article, "Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia"
(Circulation, 2011)
We thank Lazdam et al and Yuan et al for their interesting
comments on our study.1 Lazdam et al point out that in our study,
birth weight in offspring of mothers with preeclampsia was significantly lower than in controls, ...
Respiratory nitric oxide and pulmonary artery pressure in children of aymara and european ancestry at high altitude*
(CHEST, 2008-11-07)
Invasive studies suggest that healthy children living at high altitude display pulmonary hypertension, but the data to support this assumption are sparse. Nitric oxide (NO) synthesized by the
respiratory epithelium regulates ...