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Sleep-disordered breathing and oxidative stress in preclinical chronic mountain sickness (excessive erythrocytosis)
(Respiratory Physiology & Neurobiology, 2013-01-22)
Abstract.
Chronic mountain sickness (CMS) is considered to be a loss of ventilatory acclimatization to high
altitude (>2500 m) resulting in marked arterial hypoxemia and polycythemia. This case-control
study explores ...
Divergent mitochondrial antioxidant activities and lung alveolar architecture in the lungs of rats and mice at high altitude
(Frontiers in Physiology, 2018)
Abstract.
Compared with mice, adult rats living at 3,600 m above sea level (SL—La Paz, Bolivia) have high hematocrit, signs of pulmonary hypertension, and low lung volume with reduced alveolar surface area. This phenotype ...
Erythropoietin and caffeine exert similar protective impact against neonatal intermittent hypoxia : apnea of prematurity and sex dimorphism
(Experimental Neurology, 2019)
Abstract.
Apnea of prematurity (AoP) is associated with severe and repeated episodes of arterial oxygen desaturation (intermittent hypoxia - IH), which in turn increases the number of apneas. So far, there is no data ...