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Does chronic mountain sickness (CMS) have perinatal origins?
(Respiratory Physiology & Neurobiology, 2007-06-29)
Abstract.
Chronic mountain sickness (CMS) occurs in 10% of male high-altitude residents. It is characterized by hypoventilation and hypoxemia but its underlying cause remains unknown. We hypothesized that CMS' origins ...
High-altitude ancestry protects against IUGR and reductions in birth weight associated with high altitude and preeclampsia
(High Altitude Medicine & Biology, 2005-02-22)
Background.
Observations consistently demonstrate diminished birth weight [BW] with ascending altitude;
however population comparisons reveal the extent of BW
reduction depends, in part, upon high-altitude ancestry.
...
Evidence that parent-of-origin affects birth-weight reductions at high altitude
(American Journal of Human Biology, 2008-02-19)
Abstract.
Hypoxia exerts a profound depressant effect on fetal growth, lowering birth weight, and raising mortality risk. Multigenerational high-altitude populations are relatively protected from this birth-weight decline, ...