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Oxidative-nitrosative stress and systemic vascular function in highlanders with and without exaggerated hypoxemia
(CHEST, 2013-02-01)
Background: Acute exposure to high altitude stimulates free radical formation in lowlanders, yet
whether this persists during chronic exposure in healthy, well-adapted and maladapted highlanders suffering from chronic ...
Exaggerated pulmonary hypertension and right ventricular dysfunction in high-altitude dwellers with patent foramen ovale
(Chest, 2015)
There is considerable interindividual variability in pulmonary artery pressure among high-altitude (HA) dwellers, but the underlying mechanism is not known. At low altitude, a patent foramen
ovale (PFO) is present in about ...
EPR spectroscopic evidence of iron-catalysed free radical formation in chronic mountain sickness : dietary causes and vascualr consequences
(Free Radical Biology and Medicine, 2022)
Abstract
Chronic mountain sickness (CMS) is a high-altitude (HA) maladaptation syndrome characterised by elevated systemic oxidative-nitrosative stress (OXNOS) due to a free radical-mediated reduction in vascular nitric ...
Exaggerated systemic oxidative-inflammatory-nitrosative stress in chronic mountain sIckness is associated with cognitive decline and depression
(J Physiol, 2019)
Abstract.
Chronic mountain sickness (CMS) is a maladaptation syndrome encountered at high altitude (HA) characterised by severe hypoxaemia that carries a higher risk of stroke and migraine and is associated with increased ...
Sleep-disordered breathing and vascular function in patients with chronic mountain sickness and healthy high-altitude dwellers
(CHEST, 2016-11-05)
BACKGROUND: Chronic mountain sickness (CMS) is often associated with vascular
dysfunction, but the underlying mechanism is unknown. Sleep-disordered breathing (SDB)
frequently occurs at high altitude. At low altitude, ...