Show simple item record

dc.contributor.authorDesplanches, D
dc.contributor.authorHoppeler, H
dc.contributor.authorTüscher, L
dc.contributor.authorMayet, MH
dc.contributor.authorSpielvogel, H
dc.contributor.authorFerretti, G
dc.contributor.authorKayser, B
dc.contributor.authorLeuenberger, M
dc.contributor.authorGrünenfelder, A
dc.contributor.authorFavier, R
dc.date.accessioned2017-09-25T15:11:11Z
dc.date.available2017-09-25T15:11:11Z
dc.date.issued1996
dc.identifier.urihttp://repositorio.umsa.bo/xmlui/handle/123456789/12506
dc.description.abstractAbstract Twenty healthy high-altitude natives, residents of La Paz, Bolivia (3,600 m), participated in 6 wk of endurance exercise training on bicycle ergometers, 5 times/wk, 30 min/session, as previously described in normoxia-trained sea-level natives (H. Hoppeler, H. Howald, K. E. Conley, S. L. Lindstedt, H. Claassen, P. Vock, and E. R. Weibel. J. Appl. Physiol. 59: 320-327, 1985). A first group of 10 subjects was trained in chronic hypoxia (HT; barometric pressure = 500 mmHg; inspired O2 fraction = 0.209); a second group of 10 subjects was trained in acute normoxia (NT; barometric pressure = 500 mmHg; inspired O2 fraction = 0.314). The workloads were adjusted to approximately 70% of peak O2 consumption (VO2peak) measured either in hypoxia for the HT group or in normoxia for the NT group. VO2peak determination and biopsies of the vastus lateralis muscle were taken before and after the training program. VO2peak in the HT group was increased (14%) in a way similar to that in NT sea-level natives with the same protocol. Moreover, VO2peak in the NT group was not further increased by additional O2 delivery during the training session. HT or NT induced similar increases in muscle capillary-to-fiber ratio (26%) and capillary density (19%) as well as in the volume density of total mitochondria and citrate synthase activity (45%). It is concluded that high-altitude natives have a reduced capillarity and muscle tissue oxidative capacity; however, their training response is similar to that of sea-level residents, independent of whether training is carried out in hypobaric hypoxia or hypobaric normoxia.es_ES
dc.language.isoenes_ES
dc.publisherAmerican Physiological Societyes_ES
dc.subjectEstereología musculares_ES
dc.subjectHistoquímicaes_ES
dc.subjectActividades enzimáticases_ES
dc.titleMuscle tissue adaptations of high-altitude natives to training in chronic hypoxia or acute normoxiaes_ES
dc.typeArticlees_ES


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record