Bioenergetic studies in residents at high altitude (2,850 m) with asymptomatic Chagas'disease
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Summary - Cardiovascular response and working capacily were studied at rest and during a 125 W exercise ¡n residents at h¡gh alt¡tude (2,850 m), compar¡ng 2l asymptomatic (normal EKG) bul T. cruzi ¡nfected subiects (positive serology) to 2l healty controls (negative serology). Ages, anthropometr¡c, nutrit¡onal. and hematological data were similar in the two groups (P > 0.05), indicating the homogeneily ol lhe stud¡ed population. Cardiac ax¡s, heart rales, and oxygen uptakes, were not different between the two groups, at rest and/or during exercise (P > 0.05). At rest, d¡astolic and systolic pressures were s¡gnilicantly lower in the inlected group than ¡n the control group (P < 0.05). During exercise and recovery at the 1st and slh min, diastol¡c pressure was also significantly lower in inlected palients than in conlrol group whereas syslolic pressure was s¡gnif¡canlly lower only dur¡ng recovery al Sth min. The calculaled VO, max were similar ¡n the lwo groups, indicating a normal working capacity for the stud¡ed asymptomatic infected pat¡ents. The altitude does not seem to aflecl the responses to exerc¡se, since the results obtained at h¡gh altitude were similar to those oblained at sea level (Macedo et al., 1973).