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Specific and sensitive immunological diagnosis of Chagas'disease by competitive antibody enzime immunoassay using a Trypanosoma cruzi-specific monoclonal antibody
dc.contributor.author | Lemesre, JL | |
dc.contributor.author | Afchain, D | |
dc.contributor.author | Orozco, O | |
dc.contributor.author | Loyens, M | |
dc.contributor.author | Brenière, FS | |
dc.contributor.author | Desjeux, P | |
dc.contributor.author | Carlier, Y | |
dc.contributor.author | Martin, U | |
dc.contributor.author | Nogueira-Queiroz, JA | |
dc.contributor.author | Le Ray, D | |
dc.contributor.author | Capron, A | |
dc.date.accessioned | 2017-05-19T14:23:19Z | |
dc.date.available | 2017-05-19T14:23:19Z | |
dc.date.issued | 1986 | |
dc.identifier.uri | http://repositorio.umsa.bo/xmlui/handle/123456789/10534 | |
dc.description.abstract | Ábstract. Coexistence of Chagas' disease with leishmaniasis and T. rangeli infection in endemic areas and cross-reactivity between corresponding etiological agents can confuse the inmunodiagnosis of Chagas' disease. A discriminative serological test could therefore represent a major advance in specifc immunodiagnosis. A competitive antibody enzyme immunoassay against acomponent 5-enriched preparation, using a T. cruzi species-specific monoclonal antibody has allowed development of a specific serodiagnosis of Chagas' disease with high sensitivity (96.6% in undetermined and chronic phases of infection). This test can differentiate Chagas' disease from other cross-reacting parasitic diseases in areas where concomitant infections are unknown or suspected. | es_ES |
dc.language.iso | en | es_ES |
dc.publisher | Am. J. Trop. Med. Hyg. | es_ES |
dc.subject | DIAGNOSTICO | es_ES |
dc.subject | ENFERMEDAD DE CHAGAS | es_ES |
dc.subject | TRYPNOSOMA CRUZI-ESPECÍFICO | es_ES |
dc.title | Specific and sensitive immunological diagnosis of Chagas'disease by competitive antibody enzime immunoassay using a Trypanosoma cruzi-specific monoclonal antibody | es_ES |
dc.type | Article | es_ES |