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Acute and chronic altitude-induced cognitive dysfunction in children an adolescents
(J Pediatr., 2015-11-02)
Abstract.
OBJECTIVE:
To assess whether exposure to high altitude induces cognitive dysfunction in young healthy European children and adolescents during acute, short-term exposure to an altitude of 3450 m and in an ...
Genetic variations in the TP53 pathway in native americans strongly suggest adaptation to the high altitudes of the andes
(PLOS One, 2015-09-18)
Abstract.
The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and
LIF, rs929271) were studied in a total of ...
Perinatal hypoxia increases susceptibility to high-altitude polycythemia and attendant pulmonary vascular dysfunction
(Am J Physiol Heart Circ Physiol, 2015-04-27)
Perinatal hypoxia increases susceptibility to high-altitude polycythemia and
attendant pulmonary vascular dysfunction. Am J Physiol Heart Circ
Physiol 309: H565–H573, 2015. First published June 19, 2015;
doi:10.1152/a ...
Unique DNA methylation patterns in offspring of hypertensive pregnancy
(Clin Transl Sci., 2015)
Abstract.
Epigenomic processes are believed to play a pivotal role for the effect of environmental exposures in early life to modify disease risk throughout the lifespan. Offspring of women with hypertensive complications ...
Factores de riesgo asociados a síndrome metabólico en población habitante de 3600 y 4100 M.S.N.M.
(Rev Med La Paz, 2015-06-07)
Resumen.
Objetivos: Conocer los factores de riesgo, la magnitud y dirección de asociación
con el síndrome metabólico en sujetos de diferentes grupos etáreos que habitan
grandes alturas como en la ciudad de La Paz y El ...
Uterine artery blood flow, fetal hypoxia and fetal growth
(Philosophycal Transactions B, 2015-03-13)
Evolutionary trade-offs required for bipedalism and brain expansion influence
the pregnancy rise in uterine artery (UtA) blood flow and, in turn, reproductive
success. We consider the importance of UtA blood flow by ...
Divergent physiological responses in laboratory rats and mice raised at high altitude
(The Journal of Experimental Biology, 2015-01-29)
Abstract.
Ecological studies show that mice can be found at high altitude (HA – up to 4000 m) while rats are absent at these altitudes, and there are
no data to explain this discrepancy. We used adult laboratory rats ...
Exaggerated pulmonary hypertension and right ventricular dysfunction in high-altitude dwellers with patent foramen ovale
(Chest, 2015)
There is considerable interindividual variability in pulmonary artery pressure among high-altitude (HA) dwellers, but the underlying mechanism is not known. At low altitude, a patent foramen
ovale (PFO) is present in about ...
Rehidratación oral en deshidratación neonatal severa con hipernatremia crónica
(Rev Med La Paz, 2015)
RESUMEN
La hipernatremia crónica se presenta en neonatos con deshidratación secundaria a baja ingesta de leche materna debida a mala técnica de lactancia, se establece progresivamente y se acompaña de gran pérdida de peso. ...
Neonatal oxygenation, pulmonary hypertension, and evolutionary adaptation to high altitutde (2013 Grover Conference series)
(Pulm Circ, 2015-03)
Abstract.
Andeans and Tibetans have less altitude reduction in birth weight than do shorter-resident
groups, but only Tibetans are protected from pulmonary hypertension and chronic mountain sickness
(CMS). We hypothesized ...