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Life-long consequences of postnatal normoxia exposure in rats raised at high altitude
(J Appl Physiol., 2012)
Abstract.
We tested the hypothesis that exposure of high-altitude (HA) rats to a period of postnatal normoxia has long-term consequences on the ventilatory and hematological acclimatization in adults. Male and female HA ...
Programmation prénatale de l'acclimatation hématologique et respiratoire chez des rats de haute altitude
(Actas Club Recherché Clinique de Quebec, 2011)
Nous avons testé l’hypothèse selon laquelle l’hypoxie prénatale chez le rat aurait des
conséquences à long terme sur l’acclimatation physiologique à la haute altitude. Des rats
vivant en haute altitude (3600m, La Paz, ...
Effects of prenatal hypoxia on hematological and respiratory acclimatization to high altitude in rats
(Actas Club Recherché Clinique de Quebec, 2011)
We tested the hypothesis that prenatal hypoxia have long-term consequences on
physiological acclimatization to high altitude in rats. Male and female high-altitude rats
(3600m, La Paz, Bolivia) were exposed to normal ...
Hematocrit and hemoglobin levels at adulthood are determined by neonatal hypoxic exposure in rats living at high altitude
(High Altitude Medicine & Biology, 2010-08-08)
Introduction: In previous work performed at sea level we
reported that exposure to neonatal hypoxia impairs ventilatory and hematological responses to chronic hypoxia later in
life. These findings supported the hypothesis ...
Comparative responses of arterial oxygen saturation and heart rate durign postnatal development in rats living at high and low altitude
(Actas Club Recherché Clinique de Quebec, 2011)
We used pulse oximetry to measure arterial oxygen saturation (SpO2) and heart rate (HR)
in 4 and 14 day-old rats raised at HA (La Paz, Bolivia, 3,600 m / 12,000ft) or at sea level
(SL, Québec, Canada). SpO2 and HR were ...
Divergent mitochondrial antioxidant activities and lung alveolar architecture in the lungs of rats and mice at high altitude
(Frontiers in Physiology, 2018)
Abstract.
Compared with mice, adult rats living at 3,600 m above sea level (SL—La Paz, Bolivia) have high hematocrit, signs of pulmonary hypertension, and low lung volume with reduced alveolar surface area. This phenotype ...
Divergent physiological responses in laboratory rats and mice raised at high altitude
(The Journal of Experimental Biology, 2015-01-29)
Abstract.
Ecological studies show that mice can be found at high altitude (HA – up to 4000 m) while rats are absent at these altitudes, and there are
no data to explain this discrepancy. We used adult laboratory rats ...
Life-long consequences of postnatal normoxia exposure in rats raised at high altitude
(J Appl Physiol, 2012-03-13)
We tested the hypothesis that exposure of high-altitude (HA) rats to a period of
postnatal normoxia has long-term consequences on the ventilatory and
hematological acclimatization in adults. Male and female HA rats
(3,600 ...