Listar Producción científica por autor "Villena, Mercedes"

Mostrando ítems 41-60 de 64

    • Oxidative-nitrosative stress and systemic vascular function in highlanders with and without exaggerated hypoxemia 

      Bailey, Damian M; Rimoldi, Stefano F; Rexhay, Emrush; Pratali, Lorenza; Salinas Salmón, Carlos; Villena, Mercedes; McEneny, Jane; Young, Ian S; Nicod, Pascal; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (CHEST, 2013-02-01)
      Background: Acute exposure to high altitude stimulates free radical formation in lowlanders, yet whether this persists during chronic exposure in healthy, well-adapted and maladapted highlanders suffering from chronic ...

    • Patrones reproductivos en la altura : hipoxia o regulación cultural 

      Crognier, Emile; Villena, Mercedes; Vargas, Enrique (Rev. Arg. Antrop. Biol., 2001)

    • Percent of oxygen saturation of arterial hemoglobin among Bolivian aymara at 3,900-4000 m 

      Beall, Cynthia M; Almasy, Laura A; Blangero, John; Williams-Blangero, Sarah; Brittenham, Gary M; Strohl, Kingman P; Decker, Michael J; Vargas, Enrique; Villena, Mercedes; Soria, Rudy; Alarcón, Ana María; Gonzales, Cristina (American Journal of Physical Anthroplogy, 1999)
      ABSTRACT. A range of variation in percent of oxygen saturation of arterial hemoglobin (SaO2) among healthy individuals at a given high altitude indicates differences in physiological hypoxemia despite uniform ambient ...

    • Permormance of altitude acclimatized and non-acclimatized professional football (soccer) players at 3,600 M 

      Brutsaert, Tom D; Spielvogel, Hilde; Soria, Rudy; Araoz, Mauricio; Cáceres, Esperanza; Buzenet, Giliane; Villena, Mercedes; Paz-Zamora, Mario; Vargas, Enrique (Journal of Exercise Physiology, 2000-04-02)
      European football (soccer) matches frequently are played at the international level in mountainous regions of South America. In this study, the exercise response during cycle ergometry and the rate of football match ...

    • La pletismografía como método de apoyo diagnóstico en las enfermedades broncopulmonares en nuestro medio 

      Villena, Mercedes; Vargas, Enrique; Videa G., Ricardo (Instituto Boliviano de Biología de Altura, 1983)
      Resumen. Se trata de una comunicación preliminar de un estudio que tiene por finalidad establecer, por pletismografía corporal total, parámetros normales de la función respiratoria en personas habitantes de altura (3.600 ...

    • Poliglobulia patológica de altura, diversidad clínica y exámenes complementarios 

      Aparicio, Octavio; Antezana, Gerardo; Vargas, Enrique; Villena, Mercedes (Universidad Mayor de San Andrés, 1990)
      Abstract. Clinical and laboratory findings of 42 patients with High Altitude Polycythemia were analyzed consecutively. All patients had hemoglobin (Hb) and hematocrit (Ht) levels above 19 g/dl and 60%, respectively. Patients ...

    • Protective effect of female sex hormones against pulmonary hypertension in Bolivian high altitude natives 

      Sartori, Claudio; Allemann, Yves; Salinas Salmón, Carlos E; Turini, Pierre; Rodríguez, Armando; Hutter, Damián; Thalmann, Sébastien; Vargas, Enrique; Villena, Mercedes; Scherrer, Urs (High Altitude Medicine & Biology, 2003-02-19)
      There is abundant evidence that female sex hormones have protective effects in the systemic circulation in both animals and humans, but little is known regarding their role in the regulation of the pulmonary circulation. ...

    • Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia 

      Jayet, Pierre-Yves; Rimoldi, Stefano F; Stuber, Thomas; Salinas Salmón, Carlos E; Hutter, Damian; Rexhaj, Emrush; Thalmann, Sébastien; Schwab, Marcos; Turini, Pierre; Sartori-Cucchia, Céline; Nicod, Pascal; Villena, Mercedes; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (Circulation, 2010-07-19)
      Background—Adverse events in utero may predispose to cardiovascular disease in adulthood. The underlying mechanisms are unknown. During preeclampsia, vasculotoxic factors are released into the maternal circulation by the ...

    • Pulmonary nitric oxide in mountain dwellers 

      Beall, Cynthia M; Laskowski, Daniel; Strohl, Kingman; Soria, Rudy; Villena, Mercedes; Vargas, Enrique; Alarcón, Ana María; Gonzales, Cristina; Erzurum, Serpil C (NATURE, 2001-11-22)
      Nitric oxide is synthesized in the lungs to help regulate blood flow, and its levels have been found to drop in species native to low altitudes, including humans, upon acute exposure to reduced oxygen concentration1–3. ...

    • Pulmonary-artery pressure and exhaled nitric oxide in Bolivian and caucasian high altitude dwellers 

      Schwab, Marcos; Jayet, Pierre-Yves; Stuber, Thomas; Salinas Salmón, Carlos E; Bloch, Jonathan; Spielvogel, Hilde; Villena, Mercedes; Allemann, Yves; Sartori, Claudio; Scherrer, Urs (High Altitude Medicine & Biology, 2008)
      Abstract. There is evidence that high altitude populations may be better protected from hypoxic pulmonary hypertension than low altitude natives, but the underlying mechanism is incompletely understood. In Tibetans, ...

    • Reconstructing native American population history 

      Reich, David; Patterson, Nick; Campbell, Desmond; Tandon, Arti; Mazieres, Stéphane; Ray, Nicolas; Parra, María V; Rojas, Winston; Duque, Constanza; Mesa, Natalia; García, Luis F; Triana, Omar; Blair, Silvia; Maestre, Armanda; Dib, Juan C; Bravi, Claudio M; Bailliet, Graciela; Corach, Daniel; Hünemeier, Tábita; Bortolini, María Cátira; Salzano, Francisco M; Petzl-Erler, María Luiza; Acuña-Alonzo, Víctor; Aguilar-Salinas, Carlos; Canizales-Quinteros, Samuel; Tusié-Luna, Teresa; Riba, Laura; Rodríguez-Cruz, Maricela; López-Alarcón, Mardia; Coral-Vázquez, Ramón; Canto-Cetina, Thelma; Silva Zolezzi, Irma; Fernández-López, Juan Carlos; Contreras, Alejandra V; Jiménez-Sánchez, Gerardo; Gómez-Vázquez, María José; Molina, Julio; Carracedo, Ángel; Salas, Antonio; Gallo, Carla; Poletti, Giovanni; Witonsky, David B; Alkorta-Aranburu, Gorka; Sukernik, Rem I; Osipova, Ludmila; Fedorova, Sardana A; Vasquez, René; Villena, Mercedes; Moreau, Claudia; Barrantes, Ramiro; Pauls, David; Excoffier, Laurent; Bedoya, Gabriel; Rothhammer, Francisco; Dugoujon, Jean-Michel; Larrouy, Georges; Klitz, William; Labuda, Damián; Kidd, Judith; Kidd, Kenneth; Di Rienzo, Anna; Freimer, Nelson B; Price, Alkes L; Ruiz-Linares, Andrés (NATURE, 2012-08-16)
      The peopling of the Americas has been the subject of extensive genetic, archaeological and linguistic research; however, central questions remain unresolved1–5. One contentious issue is whether the settlement occurred ...

    • Rendimiento de futbolistas profesionales aclimatados y no aclimatados a la altura, a 3600 metros 

      Brutsaert, Tom D; Spielvogel, Hilde; Soria, Rudy; Araoz, Mauricio; Cáceres, Esperanza; Buzenet, Giliane; Villena, Mercedes; Paz-Zamora, Mariano; Vargas, Enrique (PubliCE, 2003-01-05)
      Resumen. Los partidos del Fútbol Europeo son frecuentemente jugados a nivel internacional en regiones montañosas de Sudamérica. En este estudio, fueron medidas las respuestas del ejercicio durante una ergometría en ciclo ...

    • Repercusión funcional respiratoria de sobrepeso y obesidad en habitantes de gran altura 

      Murillo Jauregui, Carla; Romero, Catherine; Gonzales, Cristina; Alarcón, Ana María; Aguilar, Martha; Villena, Mercedes (COLEGIO MEDICO DE BOLIVIA, 2016-02)
      RESUMEN. A nivel mundial se ha visto un aumento del sobrepeso y obesidad y Bolivia no es la excepción, en la ciudad de La Paz existe 19,190 casos, en Cochabamba existe 12,231, y en Santa Cruz hay 7,731 casos, según datos ...

    • Respiratory nitric oxide and pulmonary artery pressure in children of aymara and european ancestry at high altitude* 

      Stuber, Thomas; Sartori, Claudio; Salinas Salmón, Carlos E; Hutter, Damian; Thalmann, Sébastien; Turini, Pierre; Jayet, Pierre-Yves; Schwab, Marcos; Sartori-Cucchia, Céline; Villena, Mercedes; Scherrer, Urs; Allemann, Yves (CHEST, 2008-11-07)
      Invasive studies suggest that healthy children living at high altitude display pulmonary hypertension, but the data to support this assumption are sparse. Nitric oxide (NO) synthesized by the respiratory epithelium regulates ...

    • Response to letters regarding article, "Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia" 

      Rimoldi, Stefano F; Jayet, Pierre-Yves; Rexhaj, Emrush; Thalmann, Sébastien; Schwab, Marcos; Turini, Pierre; Sartori-Cucchia, Céline; Nicod, Pascal; Scherrer, Urs; Sartori, Claudio; Hutter, Damian; Stuber, Thomas; Allemann, Yves; Salinas Salmón, Carlos E; Villena, Mercedes (Circulation, 2011)
      We thank Lazdam et al and Yuan et al for their interesting comments on our study.1 Lazdam et al point out that in our study, birth weight in offspring of mothers with preeclampsia was significantly lower than in controls, ...

    • Role of genetic and environmental factors in the increased blood pressures of Bolivian blacks 

      Frisancho, A Roberto; Farrow, S; Friedenzohn, Isabel; Johnson, Tiffany; Kapp, Beth; Miranda, Christina; Pérez, María; Rauchle, Isha; Sánchez, Nicholas; Wheatcroft, Gloria; Woodill, Lita; Ayllón, Irma; Bellido, Diva; Rodríguez, Armando; Machicao, Jorge; Villena, Mercedes; Vargas, Enrique (American Journal of Human Biology, 1999)
      Abstract. The tendency toward hypertension or higher blood pressure is more common in blacks than whites. The factors that account for these differences are attributed to both environmental and genetic factors. To clarify ...

    • RV contractility and exercise-induced pulmonary hypertension in chronic mountain sickness : a stress echocardiographic and tissue doppler imaging study 

      Pratali, Lorenza; Allemann, Yves; Rimoldi, Stefano F; Faita, Francesco; Hutter, Damian; Rexhaj, Emrush; Brenner, Roman; Bailey, Damian M; Sartori, Claudio; Salinas Salmón, Carlos E; Villena, Mercedes; Scherrer, Urs; Picano, Eugenio; Sicari, Rosa (ELSEVIER, 2013-12)
      Objectives. The aim of this study was to evaluate right ventricular (RV) and left ventricular function and pulmonary circulation in chronic mountain sickness (CMS) patients with rest and stress echocardiography compared ...

    • Seasonal and circadian variation in salivary testosterone in rural Bolivian men 

      Vitzthum, Virginia J; Worthman, Carol M; Beall, Cynthia M; Thornburg, Jonathan; Vargas, Enrique; Villena, Mercedes; Soria Sánchez, Rudy; Cáceres, Esperanza; Spielvogel, Hilde (American Journal of Human Biology, 2009-02-19)
      Abstract. Testosterone (T) plays a key role in the increase and maintenance of muscle mass and bone density in adult men. Life history theory predicts that environmental stress may prompt a reallocation of such investments ...

    • Sleep-disordered breathing and vascular function in patients with chronic mountain sickness and healthy high-altitude dwellers 

      Rexhaj, Emrush; Rimoldi, Stefano F; Pratali, Lorenza; Brenner, Roman; Andries, Daniela; Soria, Rodrigo; Salinas Salmón, Carlos; Villena, Mercedes; Romero, Catherine; Allemann, Yves; Lovis, Alban; Heinzer, Raphaël; Sartori, Claudio; Scherrer, Urs (CHEST, 2016-11-05)
      BACKGROUND: Chronic mountain sickness (CMS) is often associated with vascular dysfunction, but the underlying mechanism is unknown. Sleep-disordered breathing (SDB) frequently occurs at high altitude. At low altitude, ...

    • Systemic vascular dysfunction in patients with chronic mountain sickness 

      Rimoldi, Stefano F; Rexhaj, Emrush; Pratali, Lorenza; Bailey, Damian; Hutter, Damian; Faita, Francesco; Salinas Salmón, Carlos E; Villena, Mercedes; Nicod, Pascal; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (CHEST, 2012-01-01)
      Background: Chronic mountain sickness (CMS) is a major public health problem characterized by exaggerated hypoxemia and erythrocytosis. In more advanced stages, patients with CMS often present with functional and structural ...