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The relationship between perinatl hypoxia and sleep-disordered breathing in preclinical chronic mountain sickness
(High Altitude Medicine & Biology, 2010-08-08)
Introduction: Chronic intermittent hypoxia due to sleepdisordered breathing is implicated as a potential etiological
factor for chronic mountain sickness (CMS). Whether sleepdisordered breathing precedes or results from ...
Neonatal oxygenation, pulmonary hypertension, and evolutionary adaptation to high altitutde (2013 Grover Conference series)
(Pulm Circ, 2015-03)
Abstract.
Andeans and Tibetans have less altitude reduction in birth weight than do shorter-resident
groups, but only Tibetans are protected from pulmonary hypertension and chronic mountain sickness
(CMS). We hypothesized ...
Determinants of blood oxygenation during pregnancy in Andean and Europeas residents of high altitude
(Am J Physiol Regul Integr Comp Physiol, 2007-07-02)
High altitude decreases birth weight,
but this effect is diminished in long vs. short-resident, high-altitude
populations. We asked whether women from long vs. short-resident,
high-altitude populations had higher arterial ...
Inhibition of peroxisome proliferator gamma (PPARɣ) : a potential link between chronic maternal hypoxia and impaired fetal growth
(Journal of Women's Health, 2013)
Background and Objective: Chronic maternal hypoxia impairs
fetal growth and increases the incidence of intrauterine growth restriction (IUGR). To identify the mechanisms underlying these hypoxia-related effects, we evaluated ...
Uterine artery blood flow during pregnancy in high-altitude aymara women
(High Altitude Medicine & Biology, 2003-02-19)
Background.
Birth weight falls with increasing altitude as the result of
intrauterine growth restriction (IUGR) likely due, in turn, to lower uterine artery (UtA) blood flow. The altitude-associated birth weight decline
is ...
High-altitude ancestry protects against IUGR and reductions in birth weight associated with high altitude and preeclampsia
(High Altitude Medicine & Biology, 2005-02-22)
Background.
Observations consistently demonstrate diminished birth weight [BW] with ascending altitude;
however population comparisons reveal the extent of BW
reduction depends, in part, upon high-altitude ancestry.
...
Do anti-angiogenic or angiogenic factors contribute to the protection of birth weight at high altitude afforded by andean ancestry?
(Reprod Sci., 2010-09)
Abstract.
Objective: This prospective study was designed to determine whether variation in angiogenic
(placental growth factor [PlGF]) and/or anti-angiogenic (soluble fms-like tyrosine kinase [sFlt-1])
factors contribute ...
Perinatal origins of chronic mountain sickness : the role of perinatal hypoxia in the development of CMS
(Meeting VII Congress World Medicine and Physiology High Altitude, 2011)
Maternal adaptation to high-altitude pregnancy : an experiment of nature-a review
(Placenta, 2004)
A long and productive history of studies at high altitude has demonstrated that chronic hypoxia plays a key role in the aetiology of intrauterine growth restriction (IUGR) and pre-eclampsia. Susceptibility to altitude-associated ...
Reduced endothelin-1 (ET-1) and elevated nitric oxide metabolites (NOX) across pregnancy among andean vs. european women at high (3100-3600 m) altitude
(High Altitude Medicine & Biology, 2005-02-22)
Background.
A consistent reduction in infant birth
weight occurs with ascending altitude; however multigenerational high-altitude residents [Andeans] demonstrate a degree of protection from altitude-associated
IUGR ...