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Cardiac and vascular disease prior to hatching in chick embryos incubated at high altitude
(Journal of Developmental Origins of Health and Disease, 2010)
Abstract.
The partial contributions of reductions in fetal nutrition and oxygenation to slow fetal growth and a developmental origin of cardiovascular disease remain unclear. By combining high altitude with the chick ...
Acute hypoxia-reoxygenation and vascular oxygen sensing in the chicken embryo
(Physiological Reports, 2017)
Abstract.
Fetal/perinatal hypoxia is one of the most common causes of perinatal morbidity and mortality and is frequently accompannied by vascular dysfunction. However, the mechanisms involved have not been fully delineated. ...
Impacts on well-being and health by excessive rainfall and floods in Paraguay, Uruguay and Bolivia
(Springer, 2016-03-25)
Hydro-climatic anomalies are impacting the well-being of populations and increasing vector-, rodent- and water-borne diseases (H-ID) in Bolivia, Paraguay and Uruguay where extreme ENSO- linked floods have been frequent ...
Estudio funcional respiratorio en agentes de parada de la policía boliviana en La Paz y El Alto, expuestos a la contaminación ambiental
(BIOFARBO, 2010-06-25)
RESUMEN.
En Bolivia se estima que más del 70% de la
contaminación atmosférica urbana proviene de la flota
vehicular. Los agentes de parada, son policías que
controlan el tráfico vehicular, trabajo que los expone a
la ...
Maternal and fetoplacental hypoxia do not alter circulating angiogenic growth factors : the emperor's got no clothes?
(The Journal of Clinical Endocrinology & Metabolism, 2010)
ABSTRACT.
Context: Placental hypoxia alters production of angiogenic growth factors (AGFs), thought to be
causally involved in the development of the pregnancy-specific disease preeclampsia (PE).
Consistent with this, ...
Apolipoprotein E/C1/C4/C2 gene cluster diversity in two native andean populations : Aymaras and Quechuas
(Annals of Human Genetics, 2012-07)
Summary.
The APOE/C1/C4/C2 gene cluster presents high relevance in lipid metabolism and, therefore, has important epidemiological implications. Here, we study for the first time the variation patterns of 25 polymorphisms ...
Hypoglycemia and the origin of hypoxia-induced reduction in human fetal growth
(PLOS One, 2010-01)
Abtract.
Background: The most well known reproductive consequence of residence at high altitude (HA .2700 m) is reduction in
fetal growth. Reduced fetoplacental oxygenation is an underlying cause of pregnancy pathologies, ...
Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas
(PLOS Genetics, 2012-03-08)
Abstract.
Most individuals throughout the Americas are admixed descendants of Native American, European, and African ancestors.
Complex historical factors have resulted in varying proportions of ancestral contributions ...
Divergent physiological responses in laboratory rats and mice raised at high altitude
(The Journal of Experimental Biology, 2015-01-29)
Abstract.
Ecological studies show that mice can be found at high altitude (HA – up to 4000 m) while rats are absent at these altitudes, and there are
no data to explain this discrepancy. We used adult laboratory rats ...
Salud pulmonar y contaminación ambiental en comerciantes de las ciudades de La Paz y El Alto
(BIOFARBO, 2010-06-20)
RESUMEN.
El estudio fue realizado en los comerciantes de la vía
pública, considerados vulnerables a adquirir
enfermedades ambientales crónicas pulmonares por estar
gran tiempo del día expuestos a tóxicos eliminados ...