Sixty percent (60%) mean hematocrit in an andean human population permanently exposed to extreme life conditions
Fecha
2010-08-08Autor
Hanco, Iván
Spielvogel, Hilde
Soliz, Jorge
Dueñas Castillo, José Ramiro
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Introduction: Located over 5435 m, La Rinconada in the
district of Puno, Peru is the highest urban centre in the
world. This altitude, at which the barometric pressure
(BP ¼ 400 mmHg), and the partial oxygen pressure
(PpO2 ¼ 80 mmHg) are almost half from sea level values
(BP ¼ 760 mmHg; PpO2 ¼ 159 mmHg), is considered the
border line at which permanent human life is possible.
However, La Rinconada dwellers are furthermore gold
mine workers, thus exposed to additional mine hypoxia
and chemical mercury toxicity Methods: In the present
work we aimed to determine the basal physiological param
of La Rinconada residents. Hematocrit (hct), pulse, arterial
oxygen saturation (SaO2), as well as the prevalence of
chronic mountain sickness (CMS; international criteria
Xining China, 2004) was evaluated in 346 subjects (39
women and 307 men). The collected data was subdivided
in eight groups from 18 to 58 years old...