Now showing items 1-2 of 2

  • Genetic variations in the TP53 pathway in native americans strongly suggest adaptation to the high altitudes of the andes 

    Jacovas, Vanessa Cristina; Rovaris, Diego Luiz; Pérez, Orlando; Azevedo, Soledad de; Macedo, Gabriel Souza; Sandoval, José Raul; Salazar-Granara, Alberto; Villena, Mercedes; Dugoujon, Jean-Michel; Bisso-Machado, Rafael; Petzi-Erler, María Luiza; Salzano, Francisco Mauro; Ashton-Prolla, Patricia; Ramallo, Virginia; Bortolini, María Cátira (PLOS One, 2015-09-18)
    The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and LIF, rs929271) were studied in a total of 282 individuals ...
  • Latin Americans show wide-spread converso ancestry and imprint of local native ancestry on physical appearance 

    Chacón-Duque, Juan-Camilo; Adhikari, Kaustubh; Fuentes-Guajardo, Macarena; Mendoza-Revilla, Javier; Acuña-Alonzo, Víctor; Barquera, Rodrigo; Quinto-Sánchez, Mirsha; Gómez-Valdés, Jorge; Everardo Martínez, Paola; Villamil-Ramírez, Hugo; Hünemeier, Tábita; Ramallo, Virginia; Silva de Cerqueira, Caio C; Hurtado, Malena; Villegas, Valeria; Granja, Vanessa; Villena, Mercedes; Vásquez, René; Llop, Elena; Sandoval, José R; Salazar-Granara, Alberto; Parolin, María-Laura; Sandoval, Karla; Peñaloza-Espinoza, Rosenda I; Rangel-Villalobos, Héctor; Winkler, Cheryl A; Klitz, William; Bravi, Claudio; Molina, Julio; Corach, Daniel; Barrantes, Ramiro; Gomes, Verónica; Resende, Carlos; Gusmäo, Leonor; Amorin, Antonio; Xue, Yali; Dugoujon, Jean-Michel; Moral, Pedro; González-José, Rolando; Schuler-Faccini, Lavinia; Salzano, Francisco M; Bortolini, María-Cátira; Canizales-Quinteros, Samuel; Poletti, Giovanni; Gallo, Carla; Bedoya, Gabriel; Rothhammer, Francisco; Balding, David; Hellenthal, Garrett; Ruiz-Linares, Andrés (Nature communications, 2018)
    Abstract. Historical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. Using novel haplotype-based ...