• Aymara children are protected from high-altitude-induced pulmonary hypertension 

      Stuber, Thomas; Sartori, Claudio; Hutter, Damian; Salinas Salmón, Carlos E; Thalmann, Sebastien; Turini, Pierre; Jayet, Pierre-Yves; Villena, Mercedes; Scherrer, Urs; Allemann, Yves (High Altitude Medicine & Biology, 2005-02-22)
      Pulmonary hypertension is a hallmark of the adaptation to ambient lack of oxygen. This assumption is also thought to hold true for high-altitude native children, since invasive studies showed elevated pulmonary-artery pressure ...
    • Exaggerated pulmonary hypertension during mild exercise in chronic mountain sickness 

      Stuber, Thomas; Sartori, Claudio; Schwab, Marcos; Jayet, Pierre-Yves; Rimoldi, Stefano F; Garcin, Sophie; Thalmann, Sébastien; Spielvogel, Hilde; Salinas Salmón, Carlos E; Villena, Mercedes; Scherrer, Urs; Allemann, Yves (CHEST, 2010-02)
      Background: Chronic mountain sickness (CMS) is an important public health problem and is characterized by exaggerated hypoxemia, erythrocytosis, and pulmonary hypertension. While pulmonary hypertension is a leading cause ...
    • Increasing respiratory dead space improves sleep disordered breathing and hypoxemia in patients with chronic mountain sickness 

      Rexhaj, Emrush; Rimoldi, Stefano F; Jayet, Pierre-Yves; Lovis, Alban; Andries, Daniela; Salinas Salmón, Carlos E; Villena, Mercedes; Allemann, Yves; Heinzer, Raphaël; Scherrer, Urs; Sartori, Claudio (The FASEB Journal, 2011-04-25)
    • Offspring of preeclamptic mothers are predisposed to hypoxic pulmonary hypertension 

      Sartori, Claudio; Jayet, Pierre-Yves; Thalmann, Sebastien; Stuber, Thomas; Hutter, Damian; Salinas Salmón, Carlos E; Cucchia, Celine; Rodriguez, Armando; Riveros, Loyola; Spielvogel, Hilde; Allemann, Yves; Villena, Mercedes; Scherrer, Urs (High Altitude Medicine & Biology, 2005-02-22)
      Adverse events in utero may predispose to cardiovascular disease in adulthood. In preeclampsia, the diseased placenta releases circulating vasculotoxic factors that cause maternal endothelial dysfunction. These factors ...
    • Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia 

      Jayet, Pierre-Yves; Rimoldi, Stefano F; Stuber, Thomas; Salinas Salmón, Carlos E; Hutter, Damian; Rexhaj, Emrush; Thalmann, Sébastien; Schwab, Marcos; Turini, Pierre; Sartori-Cucchia, Céline; Nicod, Pascal; Villena, Mercedes; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (Circulation, 2010-07-19)
      Background—Adverse events in utero may predispose to cardiovascular disease in adulthood. The underlying mechanisms are unknown. During preeclampsia, vasculotoxic factors are released into the maternal circulation by the ...
    • Pulmonary-artery pressure and exhaled nitric oxide in Bolivian and caucasian high altitude dwellers 

      Schwab, Marcos; Jayet, Pierre-Yves; Stuber, Thomas; Salinas Salmón, Carlos E; Bloch, Jonathan; Spielvogel, Hilde; Villena, Mercedes; Allemann, Yves; Sartori, Claudio; Scherrer, Urs (High Altitude Medicine & Biology, 2008)
      Abstract. There is evidence that high altitude populations may be better protected from hypoxic pulmonary hypertension than low altitude natives, but the underlying mechanism is incompletely understood. In Tibetans, ...
    • Respiratory nitric oxide and pulmonary artery pressure in children of aymara and european ancestry at high altitude* 

      Stuber, Thomas; Sartori, Claudio; Salinas Salmón, Carlos E; Hutter, Damian; Thalmann, Sébastien; Turini, Pierre; Jayet, Pierre-Yves; Schwab, Marcos; Sartori-Cucchia, Céline; Villena, Mercedes; Scherrer, Urs; Allemann, Yves (CHEST, 2008-11-07)
      Invasive studies suggest that healthy children living at high altitude display pulmonary hypertension, but the data to support this assumption are sparse. Nitric oxide (NO) synthesized by the respiratory epithelium regulates ...
    • Response to letters regarding article, "Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia" 

      Rimoldi, Stefano F; Jayet, Pierre-Yves; Rexhaj, Emrush; Thalmann, Sébastien; Schwab, Marcos; Turini, Pierre; Sartori-Cucchia, Céline; Nicod, Pascal; Scherrer, Urs; Sartori, Claudio; Hutter, Damian; Stuber, Thomas; Allemann, Yves; Salinas Salmón, Carlos E; Villena, Mercedes (Circulation, 2011)
      We thank Lazdam et al and Yuan et al for their interesting comments on our study.1 Lazdam et al point out that in our study, birth weight in offspring of mothers with preeclampsia was significantly lower than in controls, ...