• Absence of work efficiency differences during cycle ergometry exercise in Bolivian Aymara 

      Brutsaert, Tom D; Haas, Jere D; Spielvogel, Hilde (High Altitude Medicine & Biology, 2004)
      ABSTRACT. This study tested the hypothesis that Andean natives are adapted to high altitude (HA) via high work ef ficiency during exercise in hypoxia. A total of 186 young males and females were tested in Bo livia, ...
    • Actividad protrombínica en sujetos con eritrocitosis de altura 

      Rodríguez, ZA; Quiroga, MA (Revista Médica.Órgano Oficial del Colegio Médico de La Paz, 2006)
      Resumen. La eritrocitosis de altura produce una hemoconcentración, por lo que se observa disminución de factores proteicos de la coagulación plasmática como el fibrinógeno, por lo tanto se vio la necesidad de realizar ...
    • Acute hypoxia-reoxygenation and vascular oxygen sensing in the chicken embryo 

      Mohammed, Riazuddin; Salinas, Carlos E; Giussani, Dino A; Blanco, Carlos E; Cogolludo, Ángel L; Villamor, Eduardo (Physiological Reports, 2017)
      Abstract. Fetal/perinatal hypoxia is one of the most common causes of perinatal morbidity and mortality and is frequently accompannied by vascular dysfunction. However, the mechanisms involved have not been fully delineated. ...
    • Adrenergic system in high altitude residents 

      Antezana, AM; Richalet, JP; Antezana, G; Spielvogel, H; Kacimi, R (Int. J Sports. Med, 1992)
      Abstract. Heart rate (HR) response to isoproterenol (ISO) infusion (IP) is decreased in normal sea level (SL) natives exposed to high altitude (HA). Since norepinephrine plasma concentration is higher in HA hypoxia, a ...
    • Adrenocortical suppression in highland chick embryos is restored during incubation at sea level 

      Salinas Salmón, Carlos E; Villena, Mercedes; Blanco, Carlos E; Giussani, Dino A (High Altitude Medicine & Biology, 2011)
      Abstract. By combining the chick embryo model with incubation at high altitude, this study tested the hypothesis that development at high altitude is related to a fetal origin of adrenocortical but not adrenomedullary ...
    • Altitude and infant growth in Bolivia : a longitudinal study 

      Haas, Jere D; Moreno-Black, Geraldine; Frongillo, Edward A; Pabon A, Javier; Pareja L, Gerardo; Ybarnegaray U, Jorge; Hurtado G, Luis (American Journal of Physical Anthropology, 1982)
      ABSTRACT The growth of 79 healthy, well-nourished lowland (400 M) and highland (3600 M) Bolivian infants was analyzed in a longitudinal study through the first postnatal year. Compared to low altitude infants, the high ...
    • Augmented uterine artery blood flow and oxygen delivery protect andeans from altitude-associated reductions in fetal growth 

      Julian, Colleen Glyde; Wilson, Megan J; López, Miriam; Yamashiro, Henry; Téllez, Wilma; Rodríguez, Armando; Bigham, Abigail W; Shriver, Mark D; Rodríguez, Carmelo; Vargas, Enrique; Moore, Lorna G (Am J Physiol Regul Integr Comp Physiol, 2009-02-20)
      Abstract. The effect of high altitude on reducing birth weight is markedly less in populations of high- (e.g., Andeans) relative to low-altitude origin (e.g., Europeans). Uterine artery (UA) blood flow is greater ...
    • Capacidad aeróbica de deportistas de diferentes disciplinas 

      Soria, R; Spielvogel, H (COLEGIO MEDICO DE BOLIVIA, 2016-02)
      RESUMEN Objetivos. Comprobar si el efecto de la hipoxia de altura repercute de la misma manera en las disciplinas deportivas al margen de su predominancia respecto a la dependencia del oxígeno.
    • Cardiac and vascular disease prior to hatching in chick embryos incubated at high altitude 

      Salinas, CE; Blanco, CE; Villena, M; Camm, EJ; Tuckett, JD; Weerakkody, RA; Kane, AD; Shelley, AM; Wooding, FBP; Quy, M; Giussani, DA (Journal of Developmental Origins of Health and Disease, 2010)
      Abstract. The partial contributions of reductions in fetal nutrition and oxygenation to slow fetal growth and a developmental origin of cardiovascular disease remain unclear. By combining high altitude with the chick ...
    • CEdème aigu du poumon de la haute altitude. High altitude pulmonary oedema 

      Coudert, J (Bull. Physio-path resp., 1971)
      El edema agudo de pulmón de “gran altura” aparece después de 6 a 96 horas en sujetos, con frecuencia jóvenes, sin afección cardiaca o pulmonar, que llegan rápidamente a una altura igual o superior a 3000 metros. Su aparición, ...
    • Células endoteliales y trombosis en la altura 

      Rodríguez, A; Guillon, L; Drouet, A; Quiroga, M (Revista Médica, 2005)
      RESUMEN Es bastante conocido que la hipoxia crónica produce reacciones tanto Biológicas como Fisiológicas. En estudios sobre la fisiología de la coagulación se han observado actividades diferentes sobre este mecanismo en ...
    • Chemoreflex ventilatory response to CO₂ in man at low and high altitudes 

      Lefrançois, R; Gautier, H; Pasquis, P; Cevaer, AM; Hellot, MF; Leroy, J (Respiration Physiology, 1972)
      Abstract. On man, a peripheral chemoreflex ventilatory response curve was obtained by measuring ventilatory reactions to the transient inhalation of a CO₂-rich mixture. Experiments have been performed. 1) on lowlanders ...
    • Concentración de Malondialdehido en sujetos que residen a gran altitud : estudio exploratorio 

      Melgarejo Pomar, Ingrid Gaby; Balanza Erquicia, Elfride; Torrez Colmena, Lizeth; Quisberth Barrera, Sergio; Suzaño Vargas, Pilar Leina (Rev Peru Med Exp Salud Pública, 2017-12-07)
      Resumen. El objetivo fue investigar el comportamiento del malondialdehido (MDA), biomarcador de estrés oxidativo, a grandes altitudes (3500–4200 m de altitud). Se realizó un estudio exploratorio en 91 sujetos de las ciudades ...
    • Consensus statement on chronic and subacute high altitude diseases 

      León-Velarde, Fabiola; Maggiorini, Marco; Reeves, John T; Aldashev, Almaz; Asmus, Ingrid; Bernardi, Luciano; Ge, Ri-Li; Hackett, Peter; Kobayashi, Toshio; Moore, Lorna G; Peñaloza, Dante; Richalet, Jean-Paul; Roach, Robert; Wu, Tianyi; Vargas, Enrique; Zubieta-Castillo, Gustavo; Zubieta-Calleja, Gustavo (High Altitude Medicine & Biology, 2005)
      ABSTRACT. This is an international consensus statement of an ad hoc committee formed by the In ternational Society for Mountain Medicine (ISMM) at the VI World Congress on Mountain Med icine and High Altitude Physiology ...
    • Desadaptación crónica a la vida en la altura 

      Villena Cabrera, Mercedes (Anales de la Academia Boliviana de Medicina, 2004)
      Cuando humanos o animales son transportados del nivel del mar a alturas elevadas, son expuestos a una presión disminuida de oxígeno. Como consecuencia se ponen en marcha procesos que se pueden denominar de aclimatación y ...
    • Determinants of blood oxygenation during pregnancy in Andean and Europeas residents of high altitude 

      Vargas, Marco; Vargas, Enrique; Julian, Colleen Glyde; Armaza, J Fernando; Rodríguez, Armando; Téllez, Wilma; Niermeyer, Susan; Wilson, Megan; Parra, Esteban; Shriver, Mark; Moore, Lorna G (Am J Physiol Regul Integr Comp Physiol, 2007-07-02)
      High altitude decreases birth weight, but this effect is diminished in long vs. short-resident, high-altitude populations. We asked whether women from long vs. short-resident, high-altitude populations had higher arterial ...
    • Developmental, genetic, and environmental components of aerobic capacity at high altitude 

      Frisancho, A Roberto; Frisancho, Hedy G; Milotich, Mark; Brutsaert, Tom; Albalak, Rachel; Spielvogel, Hilde; Villena, Mercedes; Vargas, Enrique; Soria, Rudy (American Journal of Physical Anthropology, 1995)
      Abstract. The aerobic capacity of 268 subjects (158 males and 110 females) was evaluated in La Paz, Bolivia situated at 3,750 m. The sample included 1) 39 high altitude rural natives (all male); 2) 67 high altitude urban ...
    • Débit et distensibilité vasculaires cutanés post-ischémiques chez l'homme 

      Seroussi, S; Durand, J; Verpillat, JM; Pradel, M; Martineaud, JP (Pflügers Arch., [1973])
    • Do cytokines contribute to the andean-associated protection from reduced fetal growth at high altitude? 

      Dávila, R Daniela; Julian, Colleen Glyde; Wilson, Megan J; Browne, Vaughn A; Rodríguez, Carmelo; Bigham, Abigail W; Shriver, Mark D; Vargas, Enrique; Moore, Lorna G (Reproductive Sciences, 2011)
      Abstract. Pro- versus anti-inflammatory cytokine balance is important for successful pregnancy. Chronic hypoxia alters cytokine levels and increases the frequency of fetal growth restriction (FGR). Multigenerational Andean ...
    • Does chronic mountain sickness (CMS) have perinatal origins? 

      Moore, Lorna G; Niermeyer, Susan; Vargas, Enrique (Respiratory Physiology & Neurobiology, 2007-06-29)
      Abstract. Chronic mountain sickness (CMS) occurs in 10% of male high-altitude residents. It is characterized by hypoventilation and hypoxemia but its underlying cause remains unknown. We hypothesized that CMS' origins ...