• 2-Substituted quinoline alkaloids as potential antileishmanial drugs 

      Fournet, Alain; Angelo Barrios, Alcira; Muñoz, Victoria; Hocquemiller, Reynald; Cavé, André; Bruneton, Jean (Antimicrobial Agents and Chemotherapy, 1993-04)
      Abstract. Ten 2-substituted quinoline alkaloids isolated from a plant used for treatment of New World cutaneous leishmaniasis have antileishmanial in vitro activities against the extracellular forms of Leishmania spp. ...
    • Aminothiol multidentate chelators against Chagas disease 

      Deharo, Eric; Loyevsky, Mark; Christy, John; Balanza, Elfride; Ruiz, Grace; Muñoz, Victoria; Gordeuk, Victor R (Experimental Parasitology, 2000)
      Abstract Three compounds of an aminothiol family of iron chelators were examined for activity against trypomastigote (human) and epimastigote (vector) forms of Trypanosoma cruzi: tetraethyl and tetramethyl derivatives of ...
    • Antiprotozoal activity of aporphine alkaloids isolated from Unonopsis buchtienii (Annonaceae) 

      Waechter, Anne-Isabelle; Cavé, André; Hocquemiller, Reynald; Bories, Christian; Muñoz, Victoria; Fournet, Alain (PHYTOTHERAPY RESERARCH, 1999)
      On a preliminary screening, substantial leishmanicidal activity was observed for the petroleum ether and alkaloidal extracts of the stem bark of Unonopsis buchtienii, the alkaloids and sterols isolated from these were ...
    • Antiprotozoal activity of dehydrozaluzanin C, a sesquiterpene lactone isolated from munnozia maronii (Asteraceae) 

      Fournet, Alain; Muñoz, Victoria; Roblot, François; Hocquemiller, Reynald; Cavé, André (PHYTOTHERAPY RESEARCH, 1993)
      The petrolelum ether extract of the leaves of Munnozia maronii was found to inhibit in vitro the growth of promastigote forms of Leishmania and epimastigote forms of Trypanosoma cruzi with and IC of 25 µg/mL. Activity-guided ...
    • Biological and chemical studies of Pera benensis, a Bolivian plant used in folk medicine as a treatment of cutaneous leishmaniasis 

      Fournet, Alain; Angelo, Alcira; Muñoz, Victoria; Roblot, François; Hocquemiller, Reynald; Cavé, André (Journal of Ethnopharmacology, 1992)
      The stem barks of Pera benensis are employed by the Chimane Indians in the Bolivian Amazonia as treatment of cutaneous leishmaniasis caused by the protozoan Leishmania braziliensis. The chloroform extracts containing ...
    • Effect of some bisbenzylisoquinoline alkaloids on American Leishmania sp. in BALB/c mice 

      Fournet, Alain; Angelo Barrios, Alcira; Muñoz, Victoria; Hocquemiller, Reynald; Cavé, André (PHYTOTHERAPY RESEARCH, 1993)
      Abstract. Four bisbenzylisoquinoline alkaloids, antioquine, berbamine, gyrocarpine and isotetrandrine were tested in BALB/c mice infected with Leishmania amazonensis (IFLA/BR/67/PH8 or MHOM/GF/84/CAY-H-142) or L. venezuelensis ...
    • Leishmanicidal and trypanocidal activities of Bolivian medicinal plants 

      Fournet, Alain; Angelo Barrios, Alcira; Muñoz, Victoria (Journal of Ethnopharmacology, 1994)
      Abstract. Cutaneous and mucocutaneous leishmaniasis are endemic diseases in South America, especially in the subandean areas of the humid lowlands of Bolivia. Fourteen plants used topically in folk medicine to treat ...