Listar Producción científica por autor "Hocquemiller, R"
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Alcaloïdes des annonacées 78. Alcaloïdes des écorces d'un duguetia spixiana de Bolivie
Rasamizafy, S; Hocquemiller, R; Cavé, A; Fournet, A (Journal of Natural Products, 1987)Abastract. The bark of Bolivian Duguetia spixiana (Annonaceae) has yielded 19 isoquinoline alkaloids, 6 of which are new. The main alkaloids belong to the 7-hydroxyaporphine type, among them, the previously undescribed ... -
Antileishmanial activity of a tetralone isolated from ampelocera edentula, a Bolivian plant used as a treatment for cutaneous Leishmaniasis
Fournet, A; Angelo Barrios, A; Muñoz, V; Hocquemiller, R; Roblot, F; Cavé, A (PLANTA MÉDICA, 1994)Abstract. The stem bark of Ampelocera edentula Kuhlm. (Ulmaceae) is used by the Chimanes Indians from Bolivia for the treatment of cutaneous leishmaniasis caused by the protozoan Leishmania braziliensis. A chloroform ... -
Antiprotozoal activity of dehydrozaluzanin C a sesquiterpene lactone isolated from munnozia maronii (Asteraceae)
Muñoz, V; Fournet, A; Roblot, F; Hocquemiller, R; Cave, A (Acta Andina, 1993) -
Antiprotozoal activity of quinoline alkaloids isolated from Galipea longiflora, a Bolivian plant used as a treatment for cutaneous Leishmaniasis
Fournet, A; Angelo Barrios, A; Muñoz, V; Hocquemiller, R; Roblot, F; Cavé, A; Richomme, P; Bruneton, J (PHYTOTHERAPY RESEARCH, 1994)Abstract. The stem bark of Galipea longiflora is used by the Chimane Indians in Bolivia for the treatment of cutaneous leishmaniasis produced by Leishmania braziliensis. Petroleum ether and chloroform extracts of stem, ... -
Effect of natural naphthoquinones in BALB/c mice infected with Leishmania amazonensis and L. venezuelensis
Fournet, A; Barrios, A Angelo; Muñoz, V; Hocquemiller, R; Cavé, A (Trop. Med. Parasitol, 1992)Abstract. Plumbagin, 3,3’-biplumbagin and 8,8'-biplumbagin are naphthoquinones isolated by activity-directed fractionation from a Bolivian plant; Pera benensis, used in folk medicine as treatment of cutaneous leishmaniasis ... -
Effect of natural Naphtoquinones in BALB/C mice infected with Leishmania amazonensis and L. Venezuelensis
Fournet, A; Angelo, A; Muñoz, V; Hocquemiller, R; Cave, A (Acta Andina, 1993) -
Isolement et synthese de l'espintanol, nouveau monoterpene antiparasitaire
Hocquemiller, R; Cortes, D; Arango, GJ; Myint, SH; Cavé, A (Journal of Natural Products, 1991)Abstract. The in vitro leishmanicidal and trypanocidal activities of a petroleum ether extract of Oxandra espintana have been investigated. Four aromatic monoterpenes were isolated, of which two are novel: espintanol ... -
Les chimanines, nouvelles quinoleines substituées en 2, isolées d'une plante bolivienne antiparasitaire : galipéa longiflora
Fournet, A; Hocquemiller, R; Roblot, F; Cavé, A; Richomme, P; Bruneton, J (Journal of Natural Products, 1993)ABSTRACT.-Petroleum ether and CHCI₃, extracts of stem, root bark, and leaves of Galipea longifora were found active in vitro against Leishmania sp. and Trypanosoma cruzi at 100 µg/ml. The activity-guided fractionation of ... -
New aporphine alkaloids from Guatteria foliosa
Mahiou, V; Roblot, F; Hocquemiller, R; Cavé, A; Rojas de Arias, A; Inchausti, A; Yaluff, G; Fournet, A; Angelo, A (Journal of Natural Products, 1994)Abstract. Four new, alkaloids were obtained from Guatteria foliosa, namely, the noraporphines (--)-3-methoxyputerine [1] and (+)-norguattevaline [2], the more highly oxidized (+)-3-methoxyguattescidine [3], and the ... -
The activity of 2-substituted quinoline alkaloids in BALB/c mice infected with Leishmanis donovani
Fournet, A; Gantier, JC; Gautheret, A; Leysalles, L; Munos, MH; Mayrargue, J; Moskowitz, H; Cavé, A; Hocquemiller, R (Journal of Antimicrobial Chemotherapy, 1994)Abstract. Potent antileishmanial activity has recently been described in vivo when certain 2-substituted quinoline alkaloids are administered to mice with cutaneous leishmaniasis. We now report the ahtileishmanial activity ...