Now showing items 1-6 of 6

    • Do anti-angiogenic or angiogenic factors contribute to the protection of birth weight at high altitude afforded by andean ancestry? 

      Dávila, R Daniela; Julian, Colleen Glyde; Wilson, Megan J; Browne, Vaughn A.; Rodríguez, Carmelo; Bigham, Abigail W; Shriver, Mark D; Vargas, Enrique; Moore, Lorna G (Reprod Sci., 2010-09)
      Abstract. Objective: This prospective study was designed to determine whether variation in angiogenic (placental growth factor [PlGF]) and/or anti-angiogenic (soluble fms-like tyrosine kinase [sFlt-1]) factors contribute ...
    • Do cytokines contribute to the andean-associated protection from reduced fetal growth at high altitude? 

      Dávila, R Daniela; Julian, Colleen Glyde; Wilson, Megan J; Browne, Vaughn A; Rodríguez, Carmelo; Bigham, Abigail W; Shriver, Mark D; Vargas, Enrique; Moore, Lorna G (Reproductive Sciences, 2011)
      Abstract. Pro- versus anti-inflammatory cytokine balance is important for successful pregnancy. Chronic hypoxia alters cytokine levels and increases the frequency of fetal growth restriction (FGR). Multigenerational Andean ...
    • High-end arteriolar resistance limits uterine artery blood flow and restricts fetal growth in preeclampsia and gestational hypertension at high altitude 

      Browne, Vaughn A; Toledo-Jaldín, Lilian; Dávila, R Daniela; López, Luis P; Yamashiro, Henry; Cioffi-Ragan, Darleen; Julian, Colleen Glyde; Wilson, Megan J; Bigham, Abigail W; Shriver, Mark D; Honigman, Benjamín; Vargas, Enrique; Roach, Robert; Moore, Lorna G (Am J Physiol Regul Integr Comp Physiol, 2011)
      The reduction in infant birth weight and increased frequency of preeclampsia (PE) in high-altitude residents have been attributed to greater placental hypoxia, smaller uterine artery (UA) diameter, and lower UA blood ...
    • Role of cytokines in altitude-associated preeclampsia 

      Dávila, R Daniela; Julian, Colleen Glyde; Browne, Vaughn A.; Toledo-Jaldín, Lillian; Wilson, Megan J; Rodríguez, Armando; Vargas, Enrique; Moore, Lorna G (Pregnancy Hypertens, 2012-01)
      Abstract. Background: Preeclampsia (PE) is more common at high than low altitude and contributes to the altitude-related decline in birth weight. Since inflammatory markers are implicated in PE, we asked if such markers ...
    • Sleep-disordered breathing and oxidative stress in preclinical chronic mountain sickness (excessive erythrocytosis) 

      Julian, Colleen Glyde; Vargas, Enrique; Gonzales, Marcelino; Dávila, R Daniela; Ladenburger, Anne; Reardon, Lindsay; Schoo, Caroline; Powers, Robert W; Lee-Chiong, Teofilo; Moore, Lorna G (Respiratory Physiology & Neurobiology, 2013-01-22)
      Abstract. Chronic mountain sickness (CMS) is considered to be a loss of ventilatory acclimatization to high altitude (>2500 m) resulting in marked arterial hypoxemia and polycythemia. This case-control study explores ...
    • The relationship between perinatl hypoxia and sleep-disordered breathing in preclinical chronic mountain sickness 

      Julian, Colleen Glyde; Vargas, Enrique; Dávila, R Daniela; Salinas Salmón, Carlos E; Rodríguez, A; Gonzales, Marcelino; Moore, Lorna G (High Altitude Medicine & Biology, 2010-08-08)
      Introduction: Chronic intermittent hypoxia due to sleepdisordered breathing is implicated as a potential etiological factor for chronic mountain sickness (CMS). Whether sleepdisordered breathing precedes or results from ...