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La cardiopatía chagásica crónica
(E.G., 1999)
En las áreas endémicas de Latinoamérica, la enfermedad de Chagas es un problema importante de salud pública, principalmente por debilitación grave debida a lesiones del corazón. De los 15 a 20 millones de personas que están ...
Impairment of monocytic function during Trypanosoma cruzi infection
(Clinical and Diagnostic Laboratory Immunology, 1994-11)
During acute infection, Trypanosoma cruzi, the etiologic agent of Chagas' disease, causes immunosuppression by mechanisms that are not fully delineated. Since mononuclear phagocytes are major target cells in trypanosomiasis, ...
High correlation between Chagas' disease serology and PCR-based detection of Trypanosoma cruzi kinetoplast DNA in Bolivian children living in an endemic area
(FEMS Microbiology Letters, 1994)
Abstract. The detection of Trypanosoma cruzi kinetoplast DNA by polymerase chain reaction (PCR) amplification is a potentially powerful tool for the parasitological diagnosis of Chagas’ disease. We have applied this technique ...
Characterization of T cell clones from Chagasic patients : predominance of CD8 surface phenotype in clones from patients with pathology
(Mem. Inst. Oswaldo Cruz, 1995)
ABSTRACT.
Human Chagas' disease, caused by the protozoan Trypanosoma cruzi, is associated with pathological processes whose mechanisms are not known. To address this question, T cell lines were developed from chronic ...
Genetic variability and microdistribution of Triatoma infestans genotypes and Trypanosoma cruzi clones in Arequipa región (Peru)
(Mem. Inst. Oswaldo Cruz, 1997)
The genetic variability of Triatoma infestans and Trypanosoma cruzi populations was studied by isoenzyme analysis in two distinct areas of Arequipa province (Peru); one, Santa Rita de Siguas, being an endemic area for ...
Immune response to Trypanosoma cruzi shed acute phase antigen in children from an endemic area for Chagas'disease in Bolivia
(Mem. Inst. Oswaldo Cruz, 1997)
A field study of the immune response to the shed acute phase antigen (SAPA) of Trypanosoma cruzi was carried out in the locality of Mizque, Cochabamba department, Bolivia. Schoolchildren (266), with an average of 8.6 ± 3.6 ...
¿Cuáles son los clones de Trypanosoma cruzi que circulan en Bolivia?
([s.n.], 1997-03)
Direct identification of Trypanosoma cruzi natural clones in vectors and mammalian hosts by polymerase chain reaction amplification
(Am. J. Trop. Med. Hyg., 1992)
Abstract. The polymerase chain reaction was used to amplify the highly variable region
of the kinetoplast minicircle of Trypanosoma cruzi directly in biological samples (feces of
infected Triatomine bugs, blood samples ...
Biological and chemical studies of Pera benensis, a Bolivian plant used in folk medicine as a treatment of cutaneous leishmaniasis
(Journal of Ethnopharmacology, 1992)
The stem barks of Pera benensis are employed by the Chimane Indians in the Bolivian Amazonia as treatment of cutaneous leishmaniasis caused by the protozoan Leishmania braziliensis. The chloroform extracts containing ...
Circulation and behaviour of two major clones of Trypanosoma cruzi in Bolivian cycles
(Mem. Inst. Oswaldo Cruz, 1996-11)
On the basis of isoenzyme studies and population genetic interpretation (Tibayrenc et al. Proc. Nat. Acad. Sci. USA, 83 : 115-119, 1986), we have previously designed a molecular identification tool of two major clones of ...