Now showing items 1-8 of 8

  • Determinants of blood oxygenation during pregnancy in Andean and Europeas residents of high altitude 

    Vargas, Marco; Vargas, Enrique; Julian, Colleen Glyde; Armaza, J Fernando; Rodriguez, Armando; Tellez, Wilma; Niermeyer, Susan; Wilson, Megan; Parra, Esteban; Shriver, Mark; Moore, Lorna G (Am J Physiol Regul Integr Comp Physiol, 2007-07-02)
    High altitude decreases birth weight, but this effect is diminished in long vs. short-resident, high-altitude populations. We asked whether women from long vs. short-resident, high-altitude populations had higher arterial ...
  • High-altitude ancestry protects against hypoxia-associated reductions in fetal growth 

    Julian, Colleen Glyde; Vargas, Enrique; Armaza, J Fernando; Wilson, Megan J; Niermeyer, Susan; Moore, Lorna G (Archives of Disease in Childhood-Fetal and Neonatal, 2007-02-28)
    Objective: The chronic hypoxia of high-altitude (>2500 m) residence has been shown to decrease birth weight in all populations studied to date. However, multigenerational high-altitude populations appear protected relative ...
  • Hypoglycemia and the origin of hypoxia-induced reduction in human fetal growth 

    Zamudio, Stacy; Torricos, Tatiana; Fik, Ewa; Oyala, Maria; Echalar, Lourdes; Pullockaran, Janet; Tutino, Emily; Martin, Brittney; Belliappa, Sonia; Balanza, Elfride; Illsley, Nicholas P (PLOS One, 2010-01)
    A b s t r a c t Background: The most well known reproductive consequence of residence at high altitude (HA .2700 m) is reduction in fetal growth. Reduced fetoplacental oxygenation is an underlying cause of pregnancy ...
  • Maternal oxygen delivery is not related to altitude- and ancestry-associated differences in human fetal growth 

    Zamudio, Stacy; Postigo, Lucrecia; Illsley, Nicholas P; Rodriguez, Carmelo; Heredia, Gladys; Brimacombe, Michael; Echalar, Lourdes; Torricos, Tatiana; Tellez, Wilma; Maldonado, Ivan; Balanza Erquicia, Elfride; Alvarez, Tatiana; Ameller, Julio; Vargas, Enrique (J Physiol, 2007-09-16)
    Fetal growth is reduced at high altitude, but the decrease is less among long-resident populations. We hypothesized that greater maternal uteroplacental O2 delivery would explain increased fetal growth in Andean natives ...
  • The role of oxygen in fetal growth 

    Salinas, CE; Villena, M; Blanco, CE; Giussani, DA (J Soc Gynecol Investig, 2003)
    Intrauterine growth retardation is a killer in obstetric medicine today. Consequently, there is great interest into the determinants of fetal growth Genes (Frayling & Hattersley, BMJ 60:89, 2001) and nutrition (Barker BMJ ...
  • The role of oxygen in prenatal growth : studies in the chick embryo 

    Giussani, Dino A; Salinas Salmón, Carlos E; Villena, Mercedes; Blanco, Carlos E (J Physiol, 2007-10-25)
    The compelling evidence linking small size at birth with later cardiovascular disease has renewed and amplified scientific and clinical interests into the determinants of fetal growth. It is accepted that genes and ...
  • Uterine artery blood flow, fetal hypoxia and fetal growth 

    Browne, Vaughn A.; Julian, Colleen G.; Toledo-Jaldín, Lilian; Cioffi-Ragan, Darleen; Vargas, Enrique; Moore, Lorna G (Philosophycal Transactions B, 2015-03-13)
    Evolutionary trade-offs required for bipedalism and brain expansion influence the pregnancy rise in uterine artery (UtA) blood flow and, in turn, reproductive success. We consider the importance of UtA blood flow by ...
  • Where the O2 goes to : preservation of human fetal oxygen delivery and consumption at high altitude 

    Postigo, Lucrecia; Heredia, Gladys; Illsley, Nicholas P; Torricos, Tatiana; Dolan, Caitlin; Echalar, Lourdes; Tellez, Wilma; Maldonado, Ivan; Brimacombe, Michael; Balanza, Elfride; Vargas, Enrique; Zamudio, Stacy (The Journal of Physiology, 2009)
    Fetal growth is decreased at high altitude (> 2700 m). We hypothesized that variation in fetal O2 delivery might account for both the altitude effect and the relative preservation of fetal growth in multigenerational ...