Greater uterine artery blood flow during pregnancy in multigenerational (Andean) than shorter-term (European) high-altitude residents
Fecha
2007Autor
Wilson, Megan J
López, Miriam
Vargas, Marco
Julian, Colleen Glyde
Téllez, Wilma
Rodríguez, Armando
Bigham, Abigail
Armaza, J Fernando
Niermeyer, Susan
Shriver, Mark
Vargas, Enrique
Moore, Lorna G
Metadatos
Mostrar el registro completo del ítemResumen
Multigenerational (Andean) compared with shorter-term (European) high-altitude
residents exhibit less hypoxia-associated reductions in birth
weight. Because differences in arterial O2 content are not responsible,
we asked whether greater pregnancy-associated increases in uterine
artery (UA) blood flow and O2 delivery were involved. Serial studies
were conducted in 42 Andean and 26 European residents of La Paz,
Bolivia (3600 m) at weeks 20, 30, 36 of pregnancy and 4 mo
postpartum using Doppler ultrasound. There were no differences
postpartum but Andean vs. European women had greater UA diameter
(0.65+- 0.01 vs. 0.56 +- 0.01 cm), cross-sectional area (33.1 +- 0.97
vs. 24.7 +- 1.18 mm2), and blood flow at week ...