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High-altitude hypoxia and echocardiographic indices of pulmonary hypertension in male and female chickens at adulthood
(Circulation Journal, 2014-06)
Background: By combining the chick embryo model with incubation at high altitude (HA), the effects of chronic hypoxia on fetal growth, fetal cardiac and aortic wall remodeling and systemic arterial blood pressure at adulthood ...
Respiratory nitric oxide and pulmonary artery pressure in children of aymara and european ancestry at high altitude*
(CHEST, 2008-11-07)
Invasive studies suggest that healthy children living at high altitude display pulmonary hypertension, but the data to support this assumption are sparse. Nitric oxide (NO) synthesized by the
respiratory epithelium regulates ...
Exaggerated exercise-induced pulmonary hypertension causes lung water accumulation and right ventricular dysfunction in patients with chronic mountain sickness
(High Altitude Medicine & Biology, 2010-08-08)
Chronic mountain sickness and cor pulmonale La Paz-Bolivia (3,600-4,100 m)
(Life on the Qinghai Tibetan plateau, 2007)
Summary.
Among the majority of inhabitants of La Paz-Bolivia (3,200-4,100 m.), the mild elevation seen in pulmonary artery pressure (PAP) has no clinical significance and is reversible on descent to lower altitude or with ...
The role of oxygen in prenatal growth : studies in the chick embryo
(J Physiol, 2007-10-25)
The compelling evidence linking small size at birth with later cardiovascular disease has renewed
and amplified scientific and clinical interests into the determinants of fetal growth. It is accepted
that genes and ...
Pulmonary-artery pressure and exhaled nitric oxide in Bolivian and caucasian high altitude dwellers
(High Altitude Medicine & Biology, 2008)
Abstract.
There is evidence
that high altitude populations may be better protected from hypoxic pulmonary hypertension than low altitude natives, but the underlying mechanism is incompletely understood. In Tibetans, ...
Adrenocortical suppression in highland chick embryos is restored during incubation at sea level
(High Altitude Medicine & Biology, 2011)
Abstract.
By combining the chick embryo model with incubation at high altitude, this study tested the hypothesis that
development at high altitude is related to a fetal origin of adrenocortical but not adrenomedullary ...
Response to letters regarding article, "Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia"
(Circulation, 2011)
We thank Lazdam et al and Yuan et al for their interesting
comments on our study.1 Lazdam et al point out that in our study,
birth weight in offspring of mothers with preeclampsia was significantly lower than in controls, ...
Increasing respiratory dead space improves sleep disordered breathing and hypoxemia in patients with chronic mountain sickness
(The FASEB Journal, 2011-04-25)
Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia
(Circulation, 2010-07-19)
Background—Adverse events in utero may predispose to cardiovascular disease in adulthood. The underlying mechanisms are unknown. During preeclampsia, vasculotoxic factors are released into the maternal circulation by the ...