Listar Producción científica por autor "Vargas, Enrique"

Mostrando ítems 1-20 de 85

    • A genomewide admixture mapping panel for hispanic/latino populations 

      Xianyun, Mao; Bigham, Abigail W; Mei, Rui; Gutiérrez, Gerardo; Weiss, Ken M; Brutsaert, Tom D; León-Velarde, Fabiola; Moore, Lorna G; Vargas, Enrique; McKeigue, Paul M; Shriver, Mark D; Parra, Esteban J (The American Journal of Human Genetics, 2007-06)
      Admixture mapping (AM) is a promising method for the identification of genetic risk factors for complex traits and diseases showing prevalence differences among populations. Efficient application of this method requires the ...

    • Andean and Tibetan patterns of adaptation to high altitude 

      Bigham, Abigail W; Wilson, Megan J; Julian, Colleen Glyde; Kiyamu, Melisa; Vargas, Enrique; León-Velarde, Fabiola; Rivera-Chira, María; Rodríguez, Carmelo; Browne, Vaughn A.; Parra, Esteban; Brutsaert, Tom D; Moore, Lorna G; Shriver, Mark D (American Journal of Human Biology, 2013-01-24)
      Objectives: High-altitude hypoxia, or decreased oxygen levels caused by low barometric pressure, challenges the ability of humans to live and reproduce. Despite these challenges, human populations have lived on the Andean ...

    • Andean compared with european women are protected from altitude-associated intrauterine growth restriction (IUGR) 

      Moore, Lorna G; Armaza, Fernando; Keyes, L; Borth, R; Niermeyer, Susan; Villena, Mercedes; MacCannell, Wendy; Vargas, Enrique (s.n., 2003)
      Abstract. Babies born at high altitude to long-term high-altitude residents weigh more than those of recent migrants from low altitude. Objective: We asked whether a gradient exists such that persons of Andean ancestry ...

    • Andean women have greater uterine artery (UTA) enlargement during pregnancy than european residents of 3600 m. 

      Moore, Lorna G; Wilson, Megan; López, Miriam; Vargas, Marco; Parra, Esteban; Niermeyer, Susan; Aramaza, J Fernando; Vargas, Enrique ([s.n.], 2003)
      Abstract. Babies weigh less at high altitude but multi-generational high-altitude residents are protected from this birth weight decline (Moore HAMB 2001). Objective: We asked if higher arterial oxygenation and/or blood ...

    • Aportes de la pletismografía corporal total al estudio de la adaptación respiratoria a la vida en altura 

      Villena, Mercedes; Vargas, Enrique (Universidad Mayor de San Andrés, 1990)
      Resumen. Los procesos de adaptación a la vida en la altura son permanentemente estudiados y el avance de la tecnología, permite conocer aspectos cada vez más novedosos. El objetivo del estudio de parámetros respiratorios ...

    • Augmented uterine artery blood flow and oxygen delivery protect andeans from altitude-associated reductions in fetal growth 

      Julian, Colleen Glyde; Wilson, Megan J; López, Miriam; Yamashiro, Henry; Téllez, Wilma; Rodríguez, Armando; Bigham, Abigail W; Shriver, Mark D; Rodríguez, Carmelo; Vargas, Enrique; Moore, Lorna G (Am J Physiol Regul Integr Comp Physiol, 2009-02-20)
      Abstract. The effect of high altitude on reducing birth weight is markedly less in populations of high- (e.g., Andeans) relative to low-altitude origin (e.g., Europeans). Uterine artery (UA) blood flow is greater ...

    • Capacidad de difusión alvéolo capilar en niños residentes de altura 

      Vargas, Enrique; Villena, Mercedes; John, Beard; Haas, Jere; Cudkowicz, Leon (Aeronáutica de la Fuerza Aérea Boliviana, 1987)
      RESUMEN. La capacidad de difusión pulmonar (DLCO) para el monóxido de carbono fue determinada en 125 niños residentes de altura con edades que fluctuaban entre 4 y 6 años de edad. El estudio fue realizado en La Paz ...

    • Características respiratorias de los nativos de altura 

      Vargas, Enrique (Instituto Boliviano de Biología de Altura, 1970-09)

    • Chronic mountain sickness, optimal hemoglobin and heart disease 

      Vargas, Enrique; Spielvogel, Hilde (High Altitude Medicine & Biology, 2006-06)
      Abstract. For the male inhabitants of La Paz, Bolivia (3200–4100 m), and other high altitude regions in America and Asia, chronic mountain sickness (CMS) is a major health problem. Since CMS was first described by Carlos ...

    • Commentary on the consensus statement being prepared for the 6th World Congress on Mountain Medicine, Xining 2004 

      Vargas, Enrique (Journal of Qinghai Medical College, 2005)
      In, conclusion, while I agree that it is important to have a valid, cross - cultural scoring system that permits diagnosis of CMS in much the same way as does the Lake Louise system devised for AMS in the 1990s, I do not ...

    • Comparative aspects of high-altitude adaptation in human populations 

      Moore, Lorna G; Armaza, Fernando; Villena, Mercedes; Vargas, Enrique (Adv. Exp. Med. Biol., 2000)
      Abstract. The conditions and duration of high-altitude residence differ among high-altitude populations. The Tibetan Plateau is larger, more geographically remote, and appears to have been occupied for a longer period of ...

    • Comunicación del primer hallazgo de la hemoglobina mutada en Bolivia "Hb J Bolivia" 

      Galarza, Mario; Vargas, Enrique; Spielvogel, Hilde; Peñaloza, Rosario; Contreras, Gladys de; Rodríguez, Armando; Gutiérrez, Nancy (Universidad Mayor de San Andrés, 1990)
      Resumen. Se comunica la primera Hb mutada encontrada en Bolivia “J Bolivia”, siendo esta Hb de migración rápida, estable al isopropanol de mutación en cadena alfa e hiperafín. Esta variante se halló en un joven de 22 ...

    • Consensus statement on chronic and subacute high altitude diseases 

      León-Velarde, Fabiola; Maggiorini, Marco; Reeves, John T; Aldashev, Almaz; Asmus, Ingrid; Bernardi, Luciano; Ge, Ri-Li; Hackett, Peter; Kobayashi, Toshio; Moore, Lorna G; Peñaloza, Dante; Richalet, Jean-Paul; Roach, Robert; Wu, Tianyi; Vargas, Enrique; Zubieta-Castillo, Gustavo; Zubieta-Calleja, Gustavo (High Altitude Medicine & Biology, 2005)
      ABSTRACT. This is an international consensus statement of an ad hoc committee formed by the In ternational Society for Mountain Medicine (ISMM) at the VI World Congress on Mountain Med icine and High Altitude Physiology ...

    • Determinants of blood oxygenation during pregnancy in Andean and Europeas residents of high altitude 

      Vargas, Marco; Vargas, Enrique; Julian, Colleen Glyde; Armaza, J Fernando; Rodríguez, Armando; Téllez, Wilma; Niermeyer, Susan; Wilson, Megan; Parra, Esteban; Shriver, Mark; Moore, Lorna G (Am J Physiol Regul Integr Comp Physiol, 2007-07-02)
      High altitude decreases birth weight, but this effect is diminished in long vs. short-resident, high-altitude populations. We asked whether women from long vs. short-resident, high-altitude populations had higher arterial ...

    • Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas 

      Galanter, Joshua Mark; Fernández-López, Juan Carlos; Gignoux, Christopher R.; Barnholtz-Sloan, Jill; Fernández-Rozadilla, Ceres; Via, Marc; Hidalgo-Miranda, Alfredo; Contreras, Alejandra V; Uribe Figueroa, Laura; Raska, Paola; Jiménez-Sánchez, Gerardo; Silva Zolezzi, Irma; Torres, María; Ruiz Ponte, Clara; Ruiz, Yarimar; Salas, Antonio; Nguyen, Elizabeth; Eng, Celeste; Borjas, Lisbeth; Zabala, William; Barreto, Guillermo; Rondón González, Fernando; Ibarra, Adriana; Taboada, Patricia; Porras, Liliana; Moreno, Fabián; Bigham, Abigail; Gutiérrez, Gerardo; Brutsaert, Tom; León-Velarde, Fabiola; Moore, Lorna G; Vargas, Enrique; Cruz, Miguel; Escobedo, Jorge; Rodríguez-Santana, José; Rodríguez-Cintrón, William; Chapela, Rocio; Ford, Jean G; Bustamante, Carlos; Seminara, Daniela; Shriver, Mark; Ziv, Elad; Gonzalez Burchard, Esteban; Haile, Robert; Parra, Esteban; Carracedo, Ángel (PLOS Genetics, 2012-03-08)
      Abstract. Most individuals throughout the Americas are admixed descendants of Native American, European, and African ancestors. Complex historical factors have resulted in varying proportions of ancestral contributions ...

    • Developmental components of resting ventilation among high - and low-altitude andean children and adults 

      Frisancho, A Roberto; Juliao, Patricia C; Barcelona, Verónica; Kudyba, Carmela E; Amayo, Glenda; Davenport, Grecia; Knowles, Alicia; Sánchez, Dani; Villena, Mercedes; Vargas, Enrique; Soria, Rudy (American Journal of Physical Anthroplogy, 1999)
      ABSTRACT. This paper evaluates the age-associated changes of resting ventilation of 115 high- and low-altitude Aymara subjects, of whom 61 were from the rural Aymara village of Ventilla situated at an average altitude ...

    • Developmental, genetic, and environmental components of aerobic capacity at high altitude 

      Frisancho, A Roberto; Frisancho, Hedy G; Milotich, Mark; Brutsaert, Tom; Albalak, Rachel; Spielvogel, Hilde; Villena, Mercedes; Vargas, Enrique; Soria, Rudy (American Journal of Physical Anthropology, 1995)
      Abstract. The aerobic capacity of 268 subjects (158 males and 110 females) was evaluated in La Paz, Bolivia situated at 3,750 m. The sample included 1) 39 high altitude rural natives (all male); 2) 67 high altitude urban ...

    • Do anti-angiogenic or angiogenic factors contribute to the protection of birth weight at high altitude afforded by andean ancestry? 

      Dávila, R Daniela; Julian, Colleen Glyde; Wilson, Megan J; Browne, Vaughn A.; Rodríguez, Carmelo; Bigham, Abigail W; Shriver, Mark D; Vargas, Enrique; Moore, Lorna G (Reprod Sci., 2010-09)
      Abstract. Objective: This prospective study was designed to determine whether variation in angiogenic (placental growth factor [PlGF]) and/or anti-angiogenic (soluble fms-like tyrosine kinase [sFlt-1]) factors contribute ...

    • Do cytokines contribute to the andean-associated protection from reduced fetal growth at high altitude? 

      Dávila, R Daniela; Julian, Colleen Glyde; Wilson, Megan J; Browne, Vaughn A; Rodríguez, Carmelo; Bigham, Abigail W; Shriver, Mark D; Vargas, Enrique; Moore, Lorna G (Reproductive Sciences, 2011)
      Abstract. Pro- versus anti-inflammatory cytokine balance is important for successful pregnancy. Chronic hypoxia alters cytokine levels and increases the frequency of fetal growth restriction (FGR). Multigenerational Andean ...

    • Does chronic mountain sickness (CMS) have perinatal origins? 

      Moore, Lorna G; Niermeyer, Susan; Vargas, Enrique (Respiratory Physiology & Neurobiology, 2007-06-29)
      Abstract. Chronic mountain sickness (CMS) occurs in 10% of male high-altitude residents. It is characterized by hypoventilation and hypoxemia but its underlying cause remains unknown. We hypothesized that CMS' origins ...