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Sleep-disordered breathing and oxidative stress in preclinical chronic mountain sickness (excessive erythrocytosis)
(Respiratory Physiology & Neurobiology, 2013-01-22)
Abstract.
Chronic mountain sickness (CMS) is considered to be a loss of ventilatory acclimatization to high
altitude (>2500 m) resulting in marked arterial hypoxemia and polycythemia. This case-control
study explores ...
Inhibition of peroxisome proliferator-activated receptor ɣ : a potential link between chronic maternal hypoxia and impaired fetal growth
(FASEB Journal, 2014)
Abstract.
Chronic exposure to hypoxia raises the
risk of pregnancy disorders characterized by maternal
vascular dysfunction and diminished fetal growth. In an
effort to identify novel pathways for these hypoxiarelated ...
Higher estrogen levels during pregnancy in Andean than European residents of high altitude suggest differences in aromatase activity
(J Clin Endocrinol Metab, 2014-08)
Context: Uteroplacental hypoxia has been reported to lower estrogen levels in preeclampsia as the
result of reduced aromatase activity.
Objective: We asked whether the chronic hypoxia of residence at high altitude in the ...
Genetic variations in the TP53 pathway in native americans strongly suggest adaptation to the high altitudes of the andes
(PLOS One, 2015-09-18)
Abstract.
The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and
LIF, rs929271) were studied in a total of ...
Perinatal hypoxia increases susceptibility to high-altitude polycythemia and attendant pulmonary vascular dysfunction
(Am J Physiol Heart Circ Physiol, 2015-04-27)
Perinatal hypoxia increases susceptibility to high-altitude polycythemia and
attendant pulmonary vascular dysfunction. Am J Physiol Heart Circ
Physiol 309: H565–H573, 2015. First published June 19, 2015;
doi:10.1152/a ...
Unique DNA methylation patterns in offspring of hypertensive pregnancy
(Clin Transl Sci., 2015)
Abstract.
Epigenomic processes are believed to play a pivotal role for the effect of environmental exposures in early life to modify disease risk throughout the lifespan. Offspring of women with hypertensive complications ...
Calidad del informe pericial en los consultorios médico forenses de la ciudad de El Alto – enero 2010
(2012)
Se realizó un estudio Descriptivo de corte transversal con el objetivo de conocer la calidad del informe pericial que extiende el servicio de Medicina Forense que brinda el Instituto de Investigaciones Forenses en la ...
Prevalencia de infecciones asociadas a la atención de salud (IAAS) de seis servicios Hospital del Niño “Dr. Ovidio Aliaga Uría” Ciudad de La Paz 2012
(2015)
La falta de información local sobre Infecciones Asociadas a la Atención de Salud (IAAS), tiene implicaciones sociales y económicas sorprendentes por el incremento en la morbilidad, mortalidad, costos, tratamientos y ...
Factores de riesgo asociados a síndrome metabólico en población habitante de 3600 y 4100 M.S.N.M.
(Rev Med La Paz, 2015-06-07)
Resumen.
Objetivos: Conocer los factores de riesgo, la magnitud y dirección de asociación
con el síndrome metabólico en sujetos de diferentes grupos etáreos que habitan
grandes alturas como en la ciudad de La Paz y El ...
High-altitude hypoxia and echocardiographic indices of pulmonary hypertension in male and female chickens at adulthood
(Circulation Journal, 2014-06)
Background: By combining the chick embryo model with incubation at high altitude (HA), the effects of chronic hypoxia on fetal growth, fetal cardiac and aortic wall remodeling and systemic arterial blood pressure at adulthood ...