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Respiratory nitric oxide and pulmonary artery pressure in children of aymara and european ancestry at high altitude*
(CHEST, 2008-11-07)
Invasive studies suggest that healthy children living at high altitude display pulmonary hypertension, but the data to support this assumption are sparse. Nitric oxide (NO) synthesized by the
respiratory epithelium regulates ...
Exaggerated exercise-induced pulmonary hypertension causes lung water accumulation and right ventricular dysfunction in patients with chronic mountain sickness
(High Altitude Medicine & Biology, 2010-08-08)
Pulmonary-artery pressure and exhaled nitric oxide in Bolivian and caucasian high altitude dwellers
(High Altitude Medicine & Biology, 2008)
Abstract.
There is evidence
that high altitude populations may be better protected from hypoxic pulmonary hypertension than low altitude natives, but the underlying mechanism is incompletely understood. In Tibetans, ...
Response to letters regarding article, "Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia"
(Circulation, 2011)
We thank Lazdam et al and Yuan et al for their interesting
comments on our study.1 Lazdam et al point out that in our study,
birth weight in offspring of mothers with preeclampsia was significantly lower than in controls, ...
Increasing respiratory dead space improves sleep disordered breathing and hypoxemia in patients with chronic mountain sickness
(The FASEB Journal, 2011-04-25)
Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia
(Circulation, 2010-07-19)
Background—Adverse events in utero may predispose to cardiovascular disease in adulthood. The underlying mechanisms are unknown. During preeclampsia, vasculotoxic factors are released into the maternal circulation by the ...
Protective effect of female sex hormones against pulmonary hypertension in Bolivian high altitude natives
(High Altitude Medicine & Biology, 2003-02-19)
There is abundant evidence that female sex hormones have protective effects in the systemic circulation in both animals and humans,
but little is known regarding their role in the regulation of the pulmonary circulation. ...
Aymara children are protected from high-altitude-induced pulmonary hypertension
(High Altitude Medicine & Biology, 2005-02-22)
Pulmonary hypertension is a hallmark of the adaptation to ambient lack of oxygen. This assumption is also
thought to hold true for high-altitude native children,
since invasive studies showed elevated pulmonary-artery
pressure ...
Offspring of preeclamptic mothers are predisposed to hypoxic pulmonary hypertension
(High Altitude Medicine & Biology, 2005-02-22)
Adverse events in utero may predispose to cardiovascular disease in adulthood. In preeclampsia, the diseased placenta releases circulating vasculotoxic factors
that cause maternal endothelial dysfunction. These factors ...
Exaggerated pulmonary hypertension during mild exercise in chronic mountain sickness
(CHEST, 2010-02)
Background: Chronic mountain sickness (CMS) is an important public health problem and is characterized by exaggerated hypoxemia, erythrocytosis, and pulmonary hypertension. While pulmonary hypertension is a leading cause ...